(6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

646 compounds within 3 steps: 4 in 1, 146 in 2, 496 in 3

One step

CHEBI:1146900Reach from here →
1. (6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA hydrolase
Catalysed by BAAT, ACOT6cytosolOne of 5 routes
an acyl-CoAReach from here →
1. acyl-CoA pool formation and breakdown
No catalyst recordedcytosol
(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoAReach from here →
1. Beta Oxidation of Long Chain Fatty Acid
Catalysed by ACAA1, HSD17B4, EHHADH, ACOX1peroxisome
3-oxo-(8Z,11Z,14Z,17Z,20Z,23Z)-hexacosahexaenoyl-CoAReach from here →
1. (6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA + malonyl-CoA + H(+) = 3-oxo-(8Z,11Z,14Z,17Z,20Z,23Z)-hexacosahexaenoyl-CoA + CO2 + CoA
Catalysed by ELOVL4

Two steps

(S)-carnitineReach from here →
1. (6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA hydrolase
2. Carnitine O-Palmitoyltransferase
Catalysed by BAAT, ACOT6, CPT1A, CPT1C and 1 morecytosolOne of 244 routes
an acyl-4'-phosphopantetheineReach from here →
1. acyl-CoA pool formation and breakdown
2. an acyl-CoA + H2O = an acyl-4'-phosphopantetheine + adenosine 3',5'-bisphosphate + 2 H(+)
Catalysed by NUDT19, FITM2, NUDT8cytosol

1-(9Z-octadecenoyl)-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphateReach from here →

Catalysed by ACAA1, HSD17B4, EHHADH, ACOX1 and 1 moreperoxisome

(7Z)-octadecenoyl-CoAReach from here →

Catalysed by BAAT, ACOT6, CPT1A, CPT1C and 1 morecytosolOne of 4 routes

CHEBI:15345Reach from here →

Catalysed by BAAT, ACOT6, AACScytosolOne of 2 routes

cholineReach from here →

Catalysed by BAAT, ACOT6, CHATcytosol, nucleus

CHEBI:15380Reach from here →

Catalysed by BAAT, ACOT6, ALAS1, CPNE7cytosol, mitochondrial matrixOne of 8 routes

CHEBI:15477Reach from here →

Catalysed by BAAT, ACOT6, GLYAT, GLYATL2 and 1 morecytosol, mitochondrial matrixOne of 2 routes

2-methylcrotonoyl-CoAReach from here →

Catalysed by BAAT, ACOT6, CPT1A, CPT1BcytosolOne of 2 routes

isobutyryl-CoAReach from here →

Catalysed by BAAT, ACOT6, HADHA, ACAA2 and 1 morecytosol, mitochondrial matrixOne of 3 routes

3-methylbut-2-enoyl-CoAReach from here →

Catalysed by BAAT, ACOT6, GLYATcytosol, mitochondrial matrix

isovaleryl-CoAReach from here →

Catalysed by BAAT, ACOT6, GLYAT, GLYATL2 and 1 morecytosol, mitochondrial matrixOne of 3 routes

arachidonoyl-CoAReach from here →

Catalysed by BAAT, ACOT6, SLC27A2, ACSL4 and 6 morecytosolOne of 12 routes

CHEBI:15519Reach from here →

Catalysed by BAAT, ACOT6, ACAA1, SCP2 and 1 morecytosol, peroxisomeOne of 2 routes

palmitoyl-CoAReach from here →

Catalysed by BAAT, ACOT6, SLC27A2, ACSL4 and 6 morecytosolOne of 12 routes

oleoyl-CoAReach from here →

Catalysed by BAAT, ACOT6, CPT1A, CPT1C and 1 morecytosolOne of 12 routes

phenylacetyl-CoAReach from here →

Catalysed by BAAT, ACOT6cytosolOne of 3 routes

propionyl-CoAReach from here →

Catalysed by BAAT, ACOT6, ACSS3, ACSS2 and 1 morecytosolOne of 43 routes

CHEBI:15650Reach from here →

Catalysed by BAAT, ACOT6, ZDHHC11B, NAA10 and 30 morecytosolOne of 2 routes

CHEBI:15727Reach from here →

Catalysed by BAAT, ACOT6, NAA10cytosol

CHEBI:15746Reach from here →

Catalysed by BAAT, ACOT6, SAT1, SAT2cytosolOne of 2 routes

1-acylglycerone 3-phosphateReach from here →

Catalysed by GNPATcytosol

phosphatidylethanolamineReach from here →

Catalysed by LPCAT4, LPCAT3, LPCAT2, LPCAT1 and 1 morecytosol

1,2-diacyl-sn-glycero-3-phosphocholine(1+)Reach from here →

Catalysed by LPCAT4, LPCAT3, LPCAT2, LPCAT1cytosol

11-cis-retinolReach from here →

Catalysed by BAAT, ACOT6, DGAT1, LRAT and 3 morecytosol

phosphatidic acidReach from here →

Catalysed by AGPAT2, LCLAT1, MBOAT1, MBOAT2 and 5 morecytosol, mitochondrial matrixOne of 7 routes

oxaloacetateReach from here →

Catalysed by BAAT, ACOT6, ACLYcytosol

1-acyl-sn-glycerol 3-phosphateReach from here →

Catalysed by GPAT3, GPAT2, GPAT4, GPAMcytosol, mitochondrial matrix

a cholesterol esterReach from here →

Catalysed by SOAT2, SOAT1cytosol

anilineReach from here →

Catalysed by BAAT, ACOT6, NAT2, NAT1cytosol

CHEBI:17312Reach from here →

Catalysed by BAAT, ACOT6cytosolOne of 2 routes

1-(alk-1-enyl)-2-acyl-sn-glycero-3-phosphoethanolamineReach from here →

Catalysed by LPCAT4, LPCAT3, LPCAT2, LPCAT1cytosol

L-cysteineReach from here →

Catalysed by BAAT, ACOT6, NAGScytosol, mitochondrial matrix

(7Z,10Z,13Z)-hexadecatrienoyl-CoAReach from here →

Catalysed by BAAT, ACOT6, HADHA, ACADVL and 1 morecytosol, mitochondrial matrix

a 1,2-diacyl-sn-glycerolReach from here →

Catalysed by MOGAT2, AWAT2, MOGAT1cytosol

a triacylglycerolReach from here →

Catalysed by DGAT1, MOGAT2, MOGAT3, MOGAT1 and 1 morecytosol

CHEBI:17927Reach from here →

Catalysed by BAAT, ACOT6cytosol

(5Z)-dodecenoyl-CoAReach from here →

Catalysed by BAAT, ACOT6, HADHA, ACAA2 and 1 morecytosol, mitochondrial matrixOne of 2 routes

(11Z)-docosenoyl-CoA(4-)Reach from here →

Catalysed by BAAT, ACOT6, SLC27A2, ACSL4 and 6 morecytosolOne of 6 routes

(7Z)-tetradecenoyl-CoAReach from here →

Catalysed by BAAT, ACOT6, SLC27A2, ACSL4 and 6 morecytosolOne of 9 routes

(4Z,7Z,10Z,13Z)-hexadecatetraenoyl-CoAReach from here →

Catalysed by BAAT, ACOT6, HADHA, ACADVL and 1 morecytosol, mitochondrial matrixOne of 3 routes

(7Z,10Z)-hexadecadienoyl-CoAReach from here →

Catalysed by BAAT, ACOT6, HADHA, ACADVL and 1 morecytosol, mitochondrial matrix

(4Z,7Z)-decadienoyl-CoAReach from here →

Catalysed by BAAT, ACOT6, ECHS1, ACAA2 and 1 morecytosol, mitochondrial matrixOne of 2 routes

(5Z)-octenoyl-CoAReach from here →

Catalysed by BAAT, ACOT6, ECHS1, ACAA2 and 1 morecytosol, mitochondrial matrixOne of 2 routes

CHEBI:27540Reach from here →

Catalysed by BAAT, ACOT6, ACSM4, ACSM1 and 4 morecytosolOne of 6 routes

elaidic acidReach from here →

Catalysed by BAAT, ACOT6, SLC27A2, ACSL4 and 6 morecytosolOne of 6 routes