(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA

1. (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA hydrolase

Catalysed by BAAT, ACOT6cytosolOne of 6 routes

1. (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate = 1-(9Z-octadecenoyl)-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphate + CoA

Catalysed by AGPAT4

1. (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA hydrolase

Catalysed by BAAT, ACOT6cytosolOne of 2 routes

1. acyl-CoA pool formation and breakdown

No catalyst recordedcytosol

1. (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA reduction

No catalyst recordedcytosolOne of 2 routes

1. Beta Oxidation of Long Chain Fatty Acid

Catalysed by ECI2, ACADL, HADHA, ECI1 and 4 moremitochondrial matrixOne of 2 routes

1. (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA + malonyl-CoA + H(+) = 3-oxo-(6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA + CO2 + CoA

Catalysed by ELOVL4

1. (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + CoA

Catalysed by LPCAT1

1. 1-octadecanoyl-sn-glycero-3-phosphate + (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA = 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphate + CoA

Catalysed by AGPAT4

1. (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA + O2 = (2E,4Z,7Z,10Z,13Z,16Z,19Z)-docosaheptaenoyl-CoA + H2O2

Catalysed by ACOX1

1. (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphate = 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphate + CoA

Catalysed by AGPAT4

1. (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA hydrolase
2. Carnitine O-Palmitoyltransferase

Catalysed by BAAT, ACOT6, CPT1A, CPT1C and 1 morecytosolOne of 244 routes

1. (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA hydrolase
2. (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + AH2 + O2 = 17R-hydroxy-(4Z,7Z,10Z,13Z,15E,19Z)-docosahexaenoate + A + H2O

Catalysed by BAAT, ACOT6, PTGS2cytosolOne of 2 routes