an S-substituted L-cysteine

1. an S-substituted L-cysteine + H2O = a thiol + pyruvate + NH4(+)

Catalysed by KYAT1, KYAT3

1. an S-substituted L-cysteine + H2O = a thiol + pyruvate + NH4(+)

Catalysed by KYAT1, KYAT3

1. an S-substituted L-cysteine + acetyl-CoA = an N-acetyl-L-cysteine-S-conjugate + CoA + H(+)

Catalysed by NAT8One of 2 routes

1. an S-substituted L-cysteine + H2O = a thiol + pyruvate + NH4(+)
2. transport of 2-hydroxybutyrate and pyruvate (cytosol to extracellular)

Catalysed by KYAT1, KYAT3, SLC16A4, SLC16A5 and 4 moreextracellular space, cytosolOne of 2 routes

1. an S-substituted L-cysteine + H2O = a thiol + pyruvate + NH4(+)
2. transport of acetoacetate and pyruvate (cytosol to mitochondria)

Catalysed by KYAT1, KYAT3mitochondrial matrix, cytosolOne of 4 routes

1. an S-substituted L-cysteine + H2O = a thiol + pyruvate + NH4(+)
2. transport of acetoacetate and pyruvate (cytosol to mitochondria)
3. (S)-3-hydroxybutanoate + 2-oxoglutarate = (R)-2-hydroxyglutarate + acetoacetate

Catalysed by KYAT1, KYAT3, ADHFE1mitochondrial matrix, cytosol

1. an S-substituted L-cysteine + H2O = a thiol + pyruvate + NH4(+)
2. (R)-3-Amino-2-methylpropanoate:pyruvate aminotransferase
3. amino-acid N-acetyltransferase (N-acetyl-L-alanine)

Catalysed by