Compound

a thiol

Compounds containing the -SH radical.

Definition from MeSH (D013438), National Library of Medicine, read 2026-09-23. NLM revises MeSH; this copy may not reflect its current record.

CHEBI:29256ChEBI

Open in the graph

Structure

2D depiction

Class: Inorganic compound
Formula: HSR
Mass: 33.073 g/mol
Charge: 0
SMILES: *S
Look it up: ChEBI

Identity from ChEBI. Not evidence.

What it touches on the way

Mechanistic reach

3 entities

3 entities reached.

0 reported hops3 assembled from the scaffold

What the reference databases state

Statements

5 statements

5 statements · 1 reference database · Subject: a thiol · Sources: Rhea

Order

a thiol is converted to a methyl thioetherCompoundRhea RHEA:18277Inferred only
a thiol is a substrate of PNKDProteinRhea RHEA:82919Inferred only
a thiol is a substrate of SUMF1ProteinRhea RHEA:51152Inferred only
a thiol is a substrate of TMT1AProteinRhea RHEA:18277Inferred only
a thiol is a substrate of TMT1BProteinRhea RHEA:18277Inferred only

Reactions

7 reactions

water+MAM03104cproton+a thiol+MAM03105c
Catalysed by USP2 or USP28 or USP36 or USP13 or OTUD5 or USP33 or CYLD or USP40 or USP48 or USP14 or USP10 or USP31 and 43 more alternatives
Reaction pageLeft to rightBalance undeterminableEC 3.4.19.12cytosol
Human-GEM MAR09490CC BY 4.0Reference data
a thiol+3'-phosphoadenylyl sulfateCHEBI:58619+adenosine 3',5'-bisphosphate+hydron
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:14637CC BY 4.0Reference data
an S-substituted L-cysteine+watera thiol+pyruvate+ammonium
Catalysed by KYAT1 or KYAT3
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:18121CC BY 4.0Reference data
a thiol+S-adenosyl-L-methioninea methyl thioether+S-adenosyl-L-homocysteine+hydron
Catalysed by TMT1B or TMT1A
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:18277CC BY 4.0Reference data
an S-substituted L-cysteinea thiol+2-aminoprop-2-enoate
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:43024CC BY 4.0Reference data
L-cysteinyl-[sulfatase]+2a thiol+dioxygenan organic disulfide+3-oxo-L-alanyl-[sulfatase]+hydrogen sulfide+water+hydron
Catalysed by SUMF1
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:51152CC BY 4.0Reference data
a thioester+watera thiol+a carboxylate+hydron
Catalysed by PNKD
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:82919CC BY 4.0Reference data

Other names

5 names

Resolves to: a thiol

Also called: MercaptanmercaptansRSHThiol
Systematic name: thiols