nicotinate

1. nicotinate + NADP(+) = NAADP(+) + nicotinamide

Catalysed by CD38

1. nicotinate(in) + urate(out) = nicotinate(out) + urate(in)

Catalysed by SLC22A12, SLC22A13inner side of the membrane, outer side of the membrane

1. orotate(out) + nicotinate(in) = orotate(in) + nicotinate(out)

Catalysed by SLC22A12inner side of the membrane, outer side of the membraneOne of 2 routes

1. 5-phospho-alpha-D-ribose 1-diphosphate + nicotinate + ATP + H2O = nicotinate beta-D-ribonucleotide + ADP + phosphate + diphosphate

Catalysed by NAPRT

1. nicotinate + NADP(+) = NAADP(+) + nicotinamide

Catalysed by CD38One of 2 routes

1. orotate(out) + nicotinate(in) = orotate(in) + nicotinate(out)
2. (S)-dihydroorotate + a quinone = orotate + a quinol

Catalysed by SLC22A12, DHODHinner side of the membrane, outer side of the membrane

1. nicotinate + NADP(+) = NAADP(+) + nicotinamide
2. purine nucleoside phosphorylase (nicotinamide)

Catalysed by CD38, PNPcytosol

1. nicotinate(in) + urate(out) = nicotinate(out) + urate(in)
2. transport of L-lactate and urate (cytosol to extracellular)
3. transport of 2-hydroxybutyrate and L-lactate (cytosol to extracellular)

Catalysed by SLC22A12, SLC22A13, SLC16A4, SLC16A5 and 5 moreinner side of the membrane, outer side of the membrane, extracellular space, cytosolOne of 2 routes

1. nicotinate(in) + urate(out) = nicotinate(out) + urate(in)
2. urate(out) + glutathione(in) = urate(in) + glutathione(out)
3. cumene hydroperoxide + 2 glutathione = 2-phenylpropan-2-ol + glutathione disulfide + H2O