Compound

S-sulfanylglutathione

Conjugate base of S-sulfanylglutathione having both carboxy groups in anionic form and a protonated primary amino group.

Definition from ChEBI (CHEBI:58905), read 2026-09-23. CC BY 4.0.

CHEBI:58905ChEBI

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Structure

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A generated conformer of S-sulfanylglutathione — one low-energy arrangement PubChem computed, not a measured structure. Hydrogens are not drawn; the formula counts them.

Class: Organic compound, anion
Formula: C10H16N3O6S2
Mass: 338.387 g/mol
Charge: -1
InChIKey: QBOLVLBSUGJHGB-WDSKDSINSA-M
SMILES: [NH3+][C@@H](CCC(=O)N[C@@H](CSS)C(=O)NCC(=O)[O-])C(=O)[O-]
Look it up: ChEBI PubChem By InChIKey

Identity from ChEBI, geometry from PubChem. Not evidence.

What it touches on the way

Mechanistic reach

3 entities

3 entities reached.

0 reported hops3 assembled from the scaffold

What the reference databases state

Statements

5 statements

5 statements · 2 reference databases · Subject: S-sulfanylglutathione · Sources: Human-GEM, Rhea

Order

S-sulfanylglutathione is a substrate of ETHE1ProteinRhea RHEA:12981Inferred only
S-sulfanylglutathione is a substrate of ETHE1ProteinHuman-GEM MAR20187Inferred only
S-sulfanylglutathione is a substrate of SQORProteinRhea RHEA:55156Inferred only
S-sulfanylglutathione is a substrate of SQORProteinRhea RHEA:62608Inferred only
S-sulfanylglutathione is a substrate of TSTD1ProteinRhea RHEA:55976Inferred only

Reactions

8 reactions

FAD+CHEBI:16856+proton+hydrogen sulfideFADH2+S-sulfanylglutathione
Catalysed by SQOR
Reaction pageLeft to rightBalancedEC 1.8.5.8GO:0005759
Human-GEM MAR20186CC BY 4.0Reference data
water+dioxygen+S-sulfanylglutathioneCHEBI:16856+2proton+sulfite
Catalysed by ETHE1
Reaction pageLeft to rightBalancedEC 1.13.11.18GO:0005759
Human-GEM MAR20187CC BY 4.0Reference data
S-sulfanylglutathione+dioxygen+watersulfite+glutathione+2hydron
Catalysed by ETHE1
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:12981CC BY 4.0Reference data
S-sulfanylglutathione+dioxygenCHEBI:85586+hydron
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:13061CC BY 4.0Reference data
a quinone+hydrogen sulfide+glutathione+hydronS-sulfanylglutathione+a quinol
Catalysed by SQOR
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:55156CC BY 4.0Reference data
thiosulfate+glutathioneS-sulfanylglutathione+sulfite+hydron
Catalysed by TSTD1
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:55976CC BY 4.0Reference data
coenzyme Q10+hydrogen sulfide+glutathione+hydronS-sulfanylglutathione+ubiquinol-10
Catalysed by SQOR
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:62608CC BY 4.0Reference data
S-sulfanylglutathione+glutathioneglutathione disulfide+hydrogen sulfide+hydron
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:79851CC BY 4.0Reference data

Other names

2 names

Resolves to: S-sulfanylglutathione

Also called: (2S)-2-azaniumyl-4-{[(1R)-1-[(carboxylatomethyl)carbamoyl]-2-disulfanylethyl]carbamoyl}butanoate
Systematic name: (2S)-2-azaniumyl-5-({(2R)-1-[(carboxylatomethyl)amino]-3-disulfanyl-1-oxopropan-2-yl}amino)-5-oxopentanoate