NAADP(+)

1. NAADPH + O2 + H(+) = NAADP(+) + H2O2

Catalysed by DUOX2, DUOX1One of 3 routes

1. 2'-phospho-cyclic ADP-ribose + nicotinate = NAADP(+)

Catalysed by CD38

1. NAADP(+) + D-glucose 6-phosphate = NAADPH + 6-phospho-D-glucono-1,5-lactone + H(+)

Catalysed by G6PD

1. 2'-phospho-cyclic ADP-ribose + nicotinate = NAADP(+)

Catalysed by CD38

1. 2'-phospho-cyclic ADP-ribose + nicotinate = NAADP(+)
2. nicotinate + NADP(+) = NAADP(+) + nicotinamide

Catalysed by CD38

1. 2'-phospho-cyclic ADP-ribose + nicotinate = NAADP(+)
2. nicotinate(in) + urate(out) = nicotinate(out) + urate(in)

Catalysed by CD38, SLC22A12, SLC22A13inner side of the membrane, outer side of the membrane

1. 2'-phospho-cyclic ADP-ribose + nicotinate = NAADP(+)
2. orotate(out) + nicotinate(in) = orotate(in) + nicotinate(out)
3. (S)-dihydroorotate + a quinone = orotate + a quinol

Catalysed by CD38, SLC22A12, DHODHinner side of the membrane, outer side of the membrane

1. 2'-phospho-cyclic ADP-ribose + nicotinate = NAADP(+)
2. nicotinate + NADP(+) = NAADP(+) + nicotinamide
3. purine nucleoside phosphorylase (nicotinamide)

Catalysed by CD38