Structure
- Class
- Organic compound
- Formula
- C6H6N2O
- Mass
- 122.127 g/mol
- Charge
- 0
- InChIKey
- DFPAKSUCGFBDDF-UHFFFAOYSA-N
- SMILES
- NC(=O)c1cccnc1
- Look it up
- ChEBIBy InChIKey
Identity from ChEBI. Not evidence — none of it carries a grade.
What it touches on the way
A finding says nicotinamide moved an endpoint. This is the biology in between: the proteins and reactions it runs through to get there. It is where to look for the two things a list of findings cannot answer — why a result might happen, and what else acts on the same machinery.
34 of these are proteins with a page of their own, and that is the door: a protein page says what else it carries, which is how one compound leads to the next.
Mechanistic reach
34 entities
34 entities reached, most connected first. Hub metabolites are excluded, so this is not a claim that the compound touches everything.
0 reported hop34 assembled from the scaffold
- PARP1ProteinUNIPROT:P09874substrate ofInferred only160 paths32 endpoints
- SIRT1ProteinUNIPROT:Q96EB6substrate ofInferred only132 paths33 endpoints
- SIRT3ProteinUNIPROT:Q9NTG7substrate ofInferred only47 paths16 endpoints
- SIRT6ProteinUNIPROT:Q8N6T7substrate ofInferred only45 paths9 endpoints
- PARP16ProteinUNIPROT:Q8N5Y8substrate ofInferred only45 paths15 endpoints
- PARP10ProteinUNIPROT:Q53GL7substrate ofInferred only45 paths15 endpoints
- SLC29A1ProteinUNIPROT:Q99808transported byInferred only41 paths41 endpoints
- PARP2ProteinUNIPROT:Q9UGN5substrate ofInferred only39 paths13 endpoints
- SIRT2ProteinUNIPROT:Q8IXJ6substrate ofInferred only35 paths7 endpoints
- SIRT4ProteinUNIPROT:Q9Y6E7substrate ofInferred only32 paths8 endpoints
- TNKS2ProteinUNIPROT:Q9H2K2substrate ofInferred only32 paths16 endpoints
- TNKSProteinUNIPROT:O95271substrate ofInferred only32 paths16 endpoints
Show the remaining 22
- PARP4ProteinUNIPROT:Q9UKK3substrate ofInferred only30 paths15 endpoints
- PARP6ProteinUNIPROT:Q2NL67substrate ofInferred only28 paths14 endpoints
- BST1ProteinUNIPROT:Q10588substrate ofInferred only19 paths10 endpoints
- SIRT5ProteinUNIPROT:Q9NXA8substrate ofInferred only18 paths6 endpoints
- CD38ProteinUNIPROT:P28907substrate ofInferred only16 paths4 endpoints
- PARP9ProteinUNIPROT:Q8IXQ6substrate ofInferred only15 paths15 endpoints
- PARP14ProteinUNIPROT:Q460N5substrate ofInferred only15 paths15 endpoints
- PARP8ProteinUNIPROT:Q8N3A8substrate ofInferred only15 paths15 endpoints
- IL1R1ProteinUNIPROT:P14778substrate ofInferred only11 paths11 endpoints
- IL1RL1ProteinUNIPROT:Q01638substrate ofInferred only10 paths10 endpoints
- NAMPTProteinUNIPROT:P43490substrate ofInferred only10 paths10 endpoints
- NNMTProteinUNIPROT:P40261substrate ofInferred only9 paths9 endpoints
- IL1RAPL1ProteinUNIPROT:Q9NZN1substrate ofInferred only8 paths8 endpoints
- IL18R1ProteinUNIPROT:Q13478substrate ofInferred only6 paths6 endpoints
- IL1RL2ProteinUNIPROT:Q9HB29substrate ofInferred only6 paths6 endpoints
- IL18RAPProteinUNIPROT:O95256substrate ofInferred only5 paths5 endpoints
- ADPRSProteinUNIPROT:Q9NX46substrate ofInferred only5 paths5 endpoints
- ART1ProteinUNIPROT:P52961substrate ofInferred only5 paths5 endpoints
- ART3ProteinUNIPROT:Q13508substrate ofInferred only3 paths3 endpoints
- IL1RAPL2ProteinUNIPROT:Q9NP60substrate ofInferred only3 paths3 endpoints
- ART4ProteinUNIPROT:Q93070substrate ofInferred only3 paths3 endpoints
- SLC29A2ProteinUNIPROT:Q14542transported byInferred only2 paths2 endpoints
Where it reaches
6 systems, 14 regions, 41 tissues, 43 transporter routes.
Loading the model…