Compound

a quinone

Benzene rings which contain two ketone moieties in any position. They can be substituted in any position except at the ketone groups.

Definition from MeSH (D016227), National Library of Medicine, read 2026-09-23. NLM revises MeSH; this copy may not reflect its current record.

CHEBI:132124ChEBI

Open in the graph

Structure

2D depiction

Class: Structural class, not a single molecule
Formula: C6O2R4
Mass: 104.063 g/mol
Charge: 0
SMILES: [1*]C1=C([2*])C(=O)C([3*])=C([4*])C1=O
Look it up: ChEBI

Identity from ChEBI. Not evidence.

What it touches on the way

Mechanistic reach

16 entities

16 entities reached.

0 reported hops16 assembled from the scaffold

Show the remaining 4

What the reference databases state

Chemical structure

a 1,4-benzosemiquinone has the functional parent a quinoneCompoundChEBI CHEBI:134225Inferred only

Statements

35 statements

35 statements · 1 reference database · Subject: a quinone · Sources: Rhea

Order

a quinone is converted to a 1,4-benzosemiquinoneCompoundRhea RHEA:65952Inferred only
a 1,4-benzosemiquinone is converted to a quinoneCompoundRhea RHEA:65952Inferred only
a quinone is converted to a 1,4-benzosemiquinoneCompoundRhea RHEA:14269Inferred only
a quinol is converted to a quinoneCompoundRhea RHEA:86659Inferred only
a quinone is converted to a quinolCompoundRhea RHEA:46160Inferred only
a quinone is converted to a quinolCompoundRhea RHEA:46164Inferred only
a quinone is converted to a quinolCompoundRhea RHEA:55376Inferred only
a quinone is converted to a quinolCompoundRhea RHEA:57888Inferred only
a quinone is converted to a quinolCompoundRhea RHEA:57892Inferred only
a quinone is converted to a quinolCompoundRhea RHEA:86659Inferred only
a quinol is converted to a quinoneCompoundRhea RHEA:55376Inferred only
a quinol is converted to a quinoneCompoundRhea RHEA:57888Inferred only

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a quinol is converted to a quinoneCompoundRhea RHEA:57892Inferred only
a quinone is metabolised by NQO1ProteinRhea RHEA:46164Inferred only
a quinone is metabolised by NQO1ProteinRhea RHEA:46160Inferred only
a quinone is metabolised by NQO2ProteinRhea RHEA:12364Inferred only
a quinone is a substrate of CBR3ProteinRhea RHEA:46164Inferred only
a quinone is a substrate of CBR4ProteinRhea RHEA:46164Inferred only
a quinone is a substrate of CRYZProteinRhea RHEA:14269Inferred only
a quinone is a substrate of CYC1ProteinRhea RHEA:11484Inferred only
a quinone is a substrate of DHODHProteinRhea RHEA:30187Inferred only
a quinone is a substrate of GPD2ProteinRhea RHEA:18977Inferred only
a quinone is a substrate of PRODHProteinRhea RHEA:23784Inferred only
a quinone is a substrate of PRODH2ProteinRhea RHEA:52512Inferred only
a quinone is a substrate of PRODH2ProteinRhea RHEA:23784Inferred only
a quinone is a substrate of SDHAProteinRhea RHEA:79831Inferred only
a quinone is a substrate of SDHAProteinRhea RHEA:79827Inferred only
a quinone is a substrate of SDHBProteinRhea RHEA:79827Inferred only
a quinone is a substrate of SDHBProteinRhea RHEA:79831Inferred only
a quinone is a substrate of SDHBProteinRhea RHEA:40523Inferred only
a quinone is a substrate of SQORProteinRhea RHEA:55156Inferred only
a quinone is a substrate of TP53I3ProteinRhea RHEA:14269Inferred only
a quinone is a substrate of UQCRFS1ProteinRhea RHEA:11484Inferred only
a quinone is a substrate of VAT1ProteinRhea RHEA:14269Inferred only
a quinone is a substrate of VAT1LProteinRhea RHEA:14269Inferred only

Reactions

53 reactions

CHEBI:58314+a quinonea 2-oxocarboxylate+a quinol
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:11272CC BY 4.0Reference data
a quinol+2Fe(III)-[cytochrome c]a quinone+2Fe(II)-[cytochrome c]+2hydron
Catalysed by CYC1 or UQCRFS1
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:11484CC BY 4.0Reference data
1-(beta-D-ribofuranosyl)-1,4-dihydronicotinamide+a quinone+hydronbeta-nicotinamide D-riboside+a quinol
Catalysed by NQO2
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:12364CC BY 4.0Reference data
an aldehyde+a quinone+watera quinol+a carboxylate+hydron
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:13881CC BY 4.0Reference data
2a quinone+NADPH(4-)+hydron2a 1,4-benzosemiquinone+NADP(3-)
Catalysed by CRYZ or TP53I3 or VAT1 or VAT1L
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:14269CC BY 4.0Reference data
a quinone+sn-glycerol 3-phosphatedihydroxyacetone phosphate+a quinol
Catalysed by GPD2
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:18977CC BY 4.0Reference data
[DsbA protein]-dithiol+a quinone[DsbA protein]-disulfide+a quinol
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:20928CC BY 4.0Reference data
CHEBI:29751+a quinoneCHEBI:32364+a quinol
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:23672CC BY 4.0Reference data
L-proline+a quinone(S)-1-pyrroline-5-carboxylate+a quinol+hydron
Catalysed by PRODH or PRODH2
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:23784CC BY 4.0Reference data
(S)-dihydroorotate+a quinoneorotate+a quinol
Catalysed by DHODH
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:30187CC BY 4.0Reference data
na quinone+nhydrogen sulfide+nhydronpolysulfur(n-2)+na quinol
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:30239CC BY 4.0Reference data
CHEBI:16183+a quinol+dioxygenmethanol+a quinone+water
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:30355CC BY 4.0Reference data

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Other names

3 names

Resolves to: a quinone

Also called: 1,4-benzoquinonesp-benzoquinonespara-benzoquinones