Compound
beta-nicotinamide D-riboside
A pyridine nucleoside consisting of nicotinamide with a β-D-ribofuranosyl moiety at the 1-position.
Definition from ChEBI (CHEBI:15927), read 2026-09-23. CC BY 4.0.
Structure
Loading the model…
- Class
- Organic compound, cation
- Formula
- C11H15N2O5
- Mass
- 255.25 g/mol
- Charge
- +1
- InChIKey
- JLEBZPBDRKPWTD-TURQNECASA-O
- SMILES
- NC(=O)c1ccc[n+]([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c1
- Look it up
- ChEBIPubChemBy InChIKey
Identity from ChEBI, geometry from PubChem. Not evidence.
What it touches on the way
Mechanistic reach
5 entities
5 entities reached.
0 reported hops5 assembled from the scaffold
- PNPProteinUNIPROT:P00491substrate ofInferred only36 paths36 endpoints
- NMN zwitterionCompoundCHEBI:16171converted toInferred only27 paths9 endpoints
- NMRK2ProteinUNIPROT:Q9NPI5substrate ofInferred only14 paths7 endpoints
- NMRK1ProteinUNIPROT:Q9NWW6substrate ofInferred only10 paths5 endpoints
- NQO2ProteinUNIPROT:P16083metabolized byInferred only8 paths8 endpoints
What the reference databases state
Statements
12 statements
12 statements · 2 reference databases · Subject: beta-nicotinamide D-riboside · Sources: Human-GEM, Rhea
- beta-nicotinamide D-riboside is converted to NMN zwitterionCompoundHuman-GEM MAR04265Inferred only
- beta-nicotinamide D-riboside is converted to NMN zwitterionCompoundRhea RHEA:14017Inferred only
- beta-nicotinamide D-riboside is converted to NMN zwitterionCompoundRhea RHEA:30815Inferred only
- NMN zwitterion is converted to beta-nicotinamide D-ribosideCompoundHuman-GEM MAR04264Inferred only
- NMN zwitterion is converted to beta-nicotinamide D-ribosideCompoundRhea RHEA:14017Inferred only
- NMN zwitterion is converted to beta-nicotinamide D-ribosideCompoundRhea RHEA:30815Inferred only
- beta-nicotinamide D-riboside is metabolised by NQO2ProteinRhea RHEA:12364Inferred only
- beta-nicotinamide D-riboside is a substrate of NMRK1ProteinRhea RHEA:14017Inferred only
- beta-nicotinamide D-riboside is a substrate of NMRK1ProteinHuman-GEM MAR04265Inferred only
- beta-nicotinamide D-riboside is a substrate of NMRK2ProteinHuman-GEM MAR04265Inferred only
- beta-nicotinamide D-riboside is a substrate of NMRK2ProteinRhea RHEA:14017Inferred only
- beta-nicotinamide D-riboside is a substrate of PNPProteinHuman-GEM MAR08791Inferred only
Reactions
8 reactions
water+NMN zwitterionbeta-nicotinamide D-riboside+phosphate(3-)
Catalysed by ACP3 or NT5C1A or NT5C3A or NT5C or NT5E or NT5C3B or NT5C1B
Reaction pageLeft to rightBalancedEC 3.1.3.5cytosol
Human-GEM MAR04264CC BY 4.0Reference data
ATP+beta-nicotinamide D-ribosideADP+proton+NMN zwitterion
Reaction pageLeft to rightBalancedEC 2.7.1.22cytosol
Human-GEM MAR04265CC BY 4.0Reference data
proton+nicotinamide+D-ribose 1-phosphatebeta-nicotinamide D-riboside+phosphate(3-)
Catalysed by PNP
Reaction pageReversibleBalancedEC 2.4.2.1cytosol
Human-GEM MAR08791CC BY 4.0Reference data
1-(beta-D-ribofuranosyl)-1,4-dihydronicotinamide+a quinone+hydronbeta-nicotinamide D-riboside+a quinol
Catalysed by NQO2
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:12364CC BY 4.0Reference data
beta-nicotinamide D-riboside+ATP(4-)NMN zwitterion+ADP(3-)+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:14017CC BY 4.0Reference data
beta-nicotinamide D-riboside+waterD-ribose+nicotinamide+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:30743CC BY 4.0Reference data
NMN zwitterion+waterbeta-nicotinamide D-riboside+hydrogenphosphate
Reaction pageDirection not assertedBalanced
Rhea RHEA:30815CC BY 4.0Reference data
beta-nicotinamide D-ribosidebeta-nicotinamide D-riboside
Reaction pageDirection not assertedBalanced
Rhea RHEA:33163CC BY 4.0Reference data
On the label
Labelled products
11 products
Source: NIH DSLD · Ingredient: beta-nicotinamide D-riboside · 11 products · Declared amount per serving: 3–300 mg (6 products)
6 labels state an amount5 do not
- Alive By ScienceLIPO NRLIPO300 mgper 1 Vegetarian Capsule(s)DSLD:264771
- BPI SportsBest Testamount not statedper 2 Capsule(s)DSLD:79574
- Cutler NutritionKingamount not statedper 2 Capsule(s)DSLD:45368
- Cutler NutritionKingamount not statedper 2 Capsule(s)DSLD:45377
- Doctor's BestBest Energy Featuring Niagen150 mgper 2 Capsule(s)DSLD:62969
- GenuinePurityNicotinamide Riboside (NR)300 mgper 2 VCapsule(s)DSLD:336121
- HigoAKG GN Men's Formulaamount not statedper 2 Tablet(s)DSLD:335768
- HigoAKG GN Women's Formulaamount not statedper 2 Tablet(s)DSLD:335769
- Renue By ScienceLipo NAD+ Complete160 mgper 2 Vegetarian Capsule(s)DSLD:319020
- Renue By ScienceLipo NR300 mgper 1 Capsule(s)DSLD:319022
- Renue By ScienceLiposomal NAD+ Complete Oral Spray3 mgper 1 Spray(s)DSLD:319000
Label record: NIH Office of Dietary Supplements · CC0
Other names
9 names
Resolves to: beta-nicotinamide D-riboside
- Also called
- 1-(beta-D-Ribofuranosyl)nicotinamideN-Ribosylnicotinamidenicotinamide ribonucleosidenicotinamide riboseNicotinamide ribosidenicotinamide-beta-ribosidenicotinamide-β-riboside
- Systematic name
- 3-carbamoyl-1-beta-D-ribofuranosylpyridinium3-carbamoyl-1-β-D-ribofuranosylpyridinium