xanthine

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

137 compounds within 3 steps: 4 in 1, 15 in 2, 118 in 3

One step

hypoxanthineReach from here →
1. hypoxanthine + NAD(+) + H2O = xanthine + NADH + H(+)
Catalysed by XDH
urateReach from here →
1. xanthine:NAD+ oxidoreductase
Catalysed by XDHcytosolOne of 6 routes
xanthosineReach from here →
1. xanthosine:orthophosphate ribosyltransferase
Catalysed by PNPcytosol
XMPReach from here →
1. XMP:pyrophosphate phosphoribosyltransferase
Catalysed by HPRT1cytosol

Two steps

ureaReach from here →
1. xanthine:NAD+ oxidoreductase
2. Peroxidase
Catalysed by XDH, MPOcytosol, nucleusOne of 3 routes
(S)-lactateReach from here →
1. xanthine:NAD+ oxidoreductase
2. urate(out) + (S)-lactate(in) = urate(in) + (S)-lactate(out)
Catalysed by XDH, SLC22A12, SLC22A13cytosol, inner side of the membrane, outer side of the membrane
CHEBI:17202Reach from here →

Three steps

2-hydroxybutyric acidReach from here →
Catalysed by XDH, SLC22A12, SLC16A4, SLC16A5 and 5 morecytosol, extracellular spaceOne of 2 routes
2-phenylpropan-2-olReach from here →

Catalysed by XDH, HPRT1cytosol

CHEBI:17208Reach from here →

Catalysed by XDHcytosol

inosineReach from here →

Catalysed by XDH, PNPcytosol

5-hydroxyisourateReach from here →

Catalysed by XDHcytosol

a dicarboxylateReach from here →

Catalysed by XDH, SLC22A6cytosol, inner side of the membrane, outer side of the membraneOne of 2 routes

2'-deoxyinosineReach from here →

Catalysed by XDH, PNPcytosolOne of 2 routes

glutarateReach from here →

Catalysed by XDH, SLC22A8cytosol, inner side of the membrane, outer side of the membraneOne of 2 routes

nicotinateReach from here →

Catalysed by XDH, SLC22A12, SLC22A13cytosol, inner side of the membrane, outer side of the membrane

D-ribose 1-phosphateReach from here →

Catalysed by PNPcytosol

(S)-lactic acidReach from here →

Catalysed by XDH, SLC22A12cytosol, extracellular space

glutathioneReach from here →

Catalysed by XDH, SLC22A13cytosol, inner side of the membrane, outer side of the membrane

IMPReach from here →

Catalysed by HPRT1, IMPDH2, IMPDH1cytosolOne of 2 routes

CHEBI:730073Reach from here →

Catalysed by XDH, MPOcytosol, nucleusOne of 3 routes

Catalysed by XDH, SLC22A13, CLIC2, GPX1 and 2 morecytosol, inner side of the membrane, outer side of the membrane

a hydroxy polyunsaturated fatty acidReach from here →

Catalysed by XDH, SLC22A13, GPX1, GPX2 and 1 morecytosol, inner side of the membrane, outer side of the membrane

tauroursodeoxycholateReach from here →

Catalysed by XDH, SLC22A13, ABCC4cytosol, inner side of the membrane, outer side of the membrane

glycoursodeoxycholateReach from here →

Catalysed by XDH, SLC22A13, ABCC4cytosol, inner side of the membrane, outer side of the membrane

(15S)-hydroxy-(5Z,8Z,11Z,13E,17Z)-eicosapentaenoateReach from here →

Catalysed by XDH, SLC22A13, GPX1, GPX4cytosol, inner side of the membrane, outer side of the membrane

(11S,15S)-dihydroxy-14(R)-S-glutathionyl-(5Z,8Z,12E)-eicosatrienoateReach from here →

Catalysed by XDH, SLC22A13, GSTP1, GSTM1 and 1 morecytosol, inner side of the membrane, outer side of the membrane

prostaglandin E3Reach from here →

Catalysed by XDH, SLC22A12cytosol, extracellular spaceOne of 4 routes

prostaglandin A2Reach from here →

Catalysed by XDH, SLC22A12cytosol, extracellular spaceOne of 2 routes

prostaglandin J2Reach from here →

Catalysed by XDH, SLC22A12cytosol, extracellular spaceOne of 2 routes

15-oxoprostaglandin F2alphaReach from here →

Catalysed by XDH, SLC22A12cytosol, extracellular spaceOne of 2 routes

prostaglandin A2-S-(R)-glutathioneReach from here →

Catalysed by XDH, SLC22A13, GSTA1, GSTM1cytosol, inner side of the membrane, outer side of the membrane

prostaglandin A2-S-(S)-glutathioneReach from here →

Catalysed by XDH, SLC22A13, GSTP1, GSTM1cytosol, inner side of the membrane, outer side of the membrane

prostaglandin J2-S-(R)-glutathioneReach from here →

Catalysed by XDH, SLC22A13, GSTA1, GSTP1 and 1 morecytosol, inner side of the membrane, outer side of the membrane

prostaglandin J2-S-(S)-glutathioneReach from here →

Catalysed by XDH, SLC22A13, GSTP1, GSTM1cytosol, inner side of the membrane, outer side of the membrane

2,4-dinitrophenyl-S-glutathioneReach from here →

Catalysed by XDH, SLC22A13, PTGES, LANCL1 and 2 morecytosol, inner side of the membrane, outer side of the membrane

acetoacetateReach from here →

Catalysed by XDH, SLC22A12, SLC16A4, SLC16A5 and 3 morecytosol, extracellular spaceOne of 2 routes

(13R)-S-glutathionyl-(14S)-hydroxy-(4Z,7Z,9E,11E,16Z,19Z)-docosahexaenoateReach from here →

Catalysed by XDH, SLC22A13, GSTM4, LTC4Scytosol, inner side of the membrane, outer side of the membrane

S-methyl glutathioneReach from here →

Catalysed by XDH, SLC22A13, MMACHCcytosol, inner side of the membrane, outer side of the membrane

indoxyl sulfateReach from here →

Catalysed by XDH, SLC22A6, SLC22A8cytosol, inner side of the membrane, outer side of the membraneOne of 2 routes

S-adenosylglutathioneReach from here →

Catalysed by XDH, SLC22A13, MMACHCcytosol, inner side of the membrane, outer side of the membrane

pyruvateReach from here →

Catalysed by XDH, SLC22A12, LDHB, LDHAL6Bcytosol, extracellular space, mitochondrial matrixOne of 7 routes

all-trans-retinoic acidReach from here →

Catalysed by XDH, SLC22A12, SLC16A4, SLC16A5 and 4 morecytosol, extracellular spaceOne of 2 routes

allantoinReach from here →

Catalysed by XDHcytosol

beta-nicotinamide D-ribosideReach from here →

Catalysed by PNPcytosol

a halide anionReach from here →

Catalysed by XDH, SLC22A13, GSTT4, GSTA4 and 21 morecytosol, inner side of the membrane, outer side of the membrane

sulfateReach from here →

Catalysed by XDH, SLC22A6, SLC25A35, SLC25A34cytosol, inner side of the membrane, outer side of the membraneOne of 2 routes

adenosineReach from here →

Catalysed by PNPcytosolOne of 4 routes

(R)-carnitineReach from here →

Catalysed by XDH, SLC22A8cytosol, inner side of the membrane, outer side of the membraneOne of 2 routes

cyanamideReach from here →

Catalysed by XDH, MPO, CA1, CA2cytosol, nucleus

uridineReach from here →

Catalysed by PNP, UPP2, UPP1cytosolOne of 2 routes