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Proteins/UNIPROT:P16083
The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinones involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis..
Function from UniProtKB (P16083), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
115 statements
115 statements · 7 reference databases · Subject: NQO2 · Sources: Bgee, Hetionet, Human Protein Atlas, Reactome, Rhea, UniProt, WikiPathways
2 reactions
proton+NADH(2-)+MAM03145cNAD(+)+MAM02829c
Reaction pageReversibleBalance undeterminableEC 1.6.5.2, 1.10.5.1cytosol
Human-GEM MAR09538CC BY 4.0Reference data
1-(beta-D-ribofuranosyl)-1,4-dihydronicotinamide+a quinone+hydronbeta-nicotinamide D-riboside+a quinol
Catalysed by
5 names
Resolves to: NQO2
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:12364CC BY 4.0Reference data