estrone 3-sulfate

1. Estrone 3-sulfate sulfohydrolase
2. transport of malonate and sulfate (cytosol to mitochondria)

Catalysed by STS, SLC25A10cytosol, mitochondrial matrixOne of 2 routes

1. estrone 3-sulfate(out) + glutarate(in) = estrone 3-sulfate(in) + glutarate(out)
2. hexanedioate + glutaryl-CoA = hexanedioyl-CoA + glutarate

Catalysed by SLC22A24, SLC22A8, SLC22A11, SUGCTinner side of the membrane, outer side of the membrane

1. Estrone 3-sulfate sulfohydrolase
2. (2R,3R)-tartrate(in) + sulfate(out) = (2R,3R)-tartrate(out) + sulfate(in)

Catalysed by STS, SLC25A14, SLC25A30cytosol, inner side of the membrane, outer side of the membraneOne of 2 routes

1. Estrone 3-sulfate sulfohydrolase
2. (S,S)-tartrate(in) + sulfate(out) = (S,S)-tartrate(out) + sulfate(in)

Catalysed by STS, SLC25A14, SLC25A30cytosol, inner side of the membrane, outer side of the membraneOne of 2 routes

1. Estrone 3-sulfate sulfohydrolase
2. (3R)-citramalate(in) + sulfate(out) = (3R)-citramalate(out) + sulfate(in)

Catalysed by STS, SLC25A14, SLC25A30cytosol, inner side of the membrane, outer side of the membraneOne of 2 routes

1. Estrone 3-sulfate sulfohydrolase
2. (3S)-citramalate(in) + sulfate(out) = (3S)-citramalate(out) + sulfate(in)

Catalysed by STS, SLC25A14, SLC25A30cytosol, inner side of the membrane, outer side of the membraneOne of 2 routes

1. transport of estrone 3-sulfate (cytosol to extracellular)
2. transport of arachidonate (cytosol to extracellular)

Catalysed by SLCO1B1extracellular space, cytosolOne of 2 routes

1. Estrone 3-sulfate sulfohydrolase
2. thiosulfate(in) + sulfate(out) = thiosulfate(out) + sulfate(in)

Catalysed by STS, SLC25A14, SLC25A30, SLC26A1 and 1 morecytosol, inner side of the membrane, outer side of the membraneOne of 2 routes

1. transport of estrone 3-sulfate (cytosol to extracellular)
2. transport of serotonin (cytosol to extracellular)

Catalysed by SLCO1B1, SLCO1A2, SLCO1B3extracellular space, cytosolOne of 2 routes

1. transport of estrone 3-sulfate (cytosol to extracellular)
2. solute carrier organic anion transporter (chenodiol)

Catalysed by SLCO1B1, SLCO1A2, SLCO1B3extracellular space, cytosolOne of 2 routes

1. transport of estrone 3-sulfate (cytosol to extracellular)
2. solute carrier organic anion transporter (S-glutathionyl-2-4-dinitrobenzene)

Catalysed by SLCO1B1, SLCO1A2, SLCO1B3extracellular space, cytosolOne of 4 routes

1. transport of estrone 3-sulfate (cytosol to extracellular)
2. transport of glycolithocholate (cytosol to extracellular)

Catalysed by SLCO1B1, SLCO1A2, SLCO1B3extracellular space, cytosolOne of 2 routes

1. transport of estrone 3-sulfate (cytosol to extracellular)
2. transport of S-glutathionyl-2-4-dinitrobenzene (cytosol to extracellular)

Catalysed by SLCO1B1, SLCO1A2, SLCO1B3extracellular space, cytosolOne of 2 routes

1. butanoate(out) + estrone 3-sulfate(in) = butanoate(in) + estrone 3-sulfate(out)
2. butanoate + ATP + CoA = butanoyl-CoA + AMP + diphosphate

Catalysed by SLC22A9, ACSM1, ACSM2A, ACSM3 and 2 moreinner side of the membrane, outer side of the membrane

1. estrone 3-sulfate(out) + glutarate(in) = estrone 3-sulfate(in) + glutarate(out)
2. glutarate + succinyl-CoA = glutaryl-CoA + succinate

Catalysed by SLC22A24, SLC22A8, SLC22A11, SUGCTinner side of the membrane, outer side of the membraneOne of 4 routes

1. propanoate(in) + estrone 3-sulfate(out) = propanoate(out) + estrone 3-sulfate(in)
2. propanoate + ATP + CoA = propanoyl-CoA + AMP + diphosphate

Catalysed by SLC22A9, ACSM3, ACSS3, ACSS2 and 1 moreinner side of the membrane, outer side of the membrane

1. transport of estrone 3-sulfate (cytosol to extracellular)
2. transport of prostaglandin E1 (cytosol to extracellular)

Catalysed by SLCO1B1extracellular space, cytosolOne of 2 routes

1. transport of estrone 3-sulfate (cytosol to extracellular)
2. transport of prostaglandin I2 (cytosol to extracellular)

Catalysed by SLCO1B1extracellular space, cytosolOne of 2 routes

1. transport of estrone 3-sulfate (cytosol to extracellular)
2. transport of prostaglandin F2alpha (cytosol to extracellular)

Catalysed by SLCO1B1extracellular space, cytosolOne of 4 routes

1. transport of estrone 3-sulfate (cytosol to extracellular)
2. transport of prostaglandin H2 (cytosol to extracellular)

Catalysed by SLCO1B1extracellular space, cytosolOne of 2 routes

1. transport of estrone 3-sulfate (cytosol to extracellular)
2. transport of prostaglandin D2 (cytosol to extracellular)

Catalysed by SLCO1B1extracellular space, cytosolOne of 2 routes

1. transport of estrone 3-sulfate (cytosol to extracellular)
2. transport of leukotriene A4 (cytosol to extracellular)

Catalysed by SLCO1B1extracellular space, cytosolOne of 2 routes

1. Estrone 3-sulfate sulfohydrolase
2. N-sulfo-D-glucosamine + H2O = D-glucosamine + sulfate

Catalysed by STS, SGSHcytosol

1. Estrone 3-sulfate sulfohydrolase
2. dehydroepiandrosterone 3-sulfate + H2O = 3beta-hydroxyandrost-5-en-17-one + sulfate + H(+)

Catalysed by STScytosolOne of 11 routes

1. transport of estrone 3-sulfate (cytosol to extracellular)
2. transport of leukotriene C4 (cytosol to extracellular)

Catalysed by SLCO1B1extracellular space, cytosolOne of 2 routes

1. Estrone 3-sulfate sulfohydrolase
2. ATP:sulfate adenylyltransferase

Catalysed by STS, PAPSS1, PAPSS2cytosolOne of 4 routes

1. transport of estrone 3-sulfate (cytosol to extracellular)
2. transport of S-glutathionyl-2-4-dinitrobenzene (cytosol to extracellular)

Catalysed by SLCO1B1, SLCO1A2, SLCO1B3extracellular space, cytosolOne of 2 routes

1. transport of estrone 3-sulfate (cytosol to extracellular)
2. transport of histamine (cytosol to extracellular)

Catalysed by SLCO1B1, SLCO1A2, SLCO1B3extracellular space, cytosolOne of 2 routes

1. transport of estrone 3-sulfate (cytosol to extracellular)
2. transport of S-glutathionyl-2-4-dinitrobenzene (cytosol to extracellular)

Catalysed by SLCO1B1, SLCO1A2, SLCO1B3extracellular space, cytosolOne of 2 routes

1. estrone 3-sulfate(out) + glutarate(in) = estrone 3-sulfate(in) + glutarate(out)
2. kynurenate(out) + glutarate(in) = kynurenate(in) + glutarate(out)

Catalysed by SLC22A24, SLC22A8, SLC22A11, SLC22A6inner side of the membrane, outer side of the membraneOne of 2 routes

1. transport of estrone 3-sulfate (cytosol to extracellular)
2. transport of dopamine (cytosol to extracellular)

Catalysed by SLCO1B1, SLCO1A2, SLCO1B3extracellular space, cytosolOne of 2 routes

1. transport of estrone 3-sulfate (cytosol to extracellular)
2. transport of S-glutathionyl-2-4-dinitrobenzene (cytosol to extracellular)

Catalysed by SLCO1B1, SLCO1A2, SLCO1B3extracellular space, cytosolOne of 2 routes

1. transport of estrone 3-sulfate (cytosol to extracellular)
2. transport of prostaglandin E2 (cytosol to extracellular)

Catalysed by SLCO1B1, SLCO1A2, SLCO1B3extracellular space, cytosolOne of 4 routes

1. Estrone 3-sulfate sulfohydrolase
2. Transport of 5-Hydroxyindoleacetate

Catalysed by STS, SLC4A1cytosol, extracellular spaceOne of 2 routes

1. transport of estrone 3-sulfate (cytosol to extracellular)
2. transport of noradrenaline (cytosol to extracellular)

Catalysed by SLCO1B1, SLCO1A2, SLCO1B3extracellular space, cytosolOne of 2 routes

1. transport of estrone 3-sulfate (cytosol to extracellular)
2. Resistance-Nodulation-Cell Division (Rnd) Tcdb:2.A.60.1.5

Catalysed by SLCO1B1extracellular space, cytosolOne of 2 routes

1. Estrone 3-sulfate sulfohydrolase
2. unspecific monooxygenase (estrone)

Catalysed by STS, CYP1A1, CYP1A2, CYP2E1 and 21 morecytosolOne of 3 routes

1. transport of estrone 3-sulfate (cytosol to extracellular)
2. transport of S-glutathionyl-2-4-dinitrobenzene (cytosol to extracellular)

Catalysed by SLCO1B1, SLCO1A2, SLCO1B3extracellular space, cytosolOne of 2 routes

1. transport of estrone 3-sulfate (cytosol to extracellular)
2. transport of prostaglandin G2 (cytosol to extracellular)

Catalysed by SLCO1B1extracellular space, cytosolOne of 2 routes

1. estrone 3-sulfate(out) + glutarate(in) = estrone 3-sulfate(in) + glutarate(out)
2. 17beta-estradiol 17-O-(beta-D-glucuronate)(out) + glutarate(in) = 17beta-estradiol 17-O-(beta-D-glucuronate)(in) + glutarate(out)

Catalysed by SLC22A24, SLC22A8, SLC22A11inner side of the membrane, outer side of the membraneOne of 2 routes

1. pentanoate(in) + estrone 3-sulfate(out) = pentanoate(out) + estrone 3-sulfate(in)
2. pentanal + NAD(+) + H2O = pentanoate + NADH + 2 H(+)

Catalysed by SLC22A9, ALDH9A1inner side of the membrane, outer side of the membrane

1. Estrone 3-sulfate sulfohydrolase
2. estrone + reduced [NADPH--hemoprotein reductase] + O2 = 4-hydroxyestrone + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Catalysed by STS, CYP1A1, CYP1A2, CYP3A4 and 3 morecytosol

1. Estrone 3-sulfate sulfohydrolase
2. estrone + reduced [NADPH--hemoprotein reductase] + O2 = 6alpha-hydroxyestrone + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Catalysed by STS, CYP1A1cytosol

1. Estrone 3-sulfate sulfohydrolase
2. estrone + reduced [NADPH--hemoprotein reductase] + O2 = 15alpha-hydroxyestrone + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Catalysed by STS, CYP1A1cytosol

1. transport of estrone 3-sulfate (cytosol to extracellular)
2. transport of S-glutathionyl-2-4-dinitrobenzene (cytosol to extracellular)

Catalysed by SLCO1B1extracellular space, cytosolOne of 2 routes

1. transport of estrone 3-sulfate (cytosol to extracellular)
2. solute carrier organic anion transporter (S-glutathionyl-2-4-dinitrobenzene)

Catalysed by SLCO1B1, SLCO1A2, SLC7A9, SLCO1B3extracellular space, cytosolOne of 2 routes

1. Estrone 3-sulfate sulfohydrolase
2. transport of chloride and sulfate (cytosol to extracellular)
3. Carnitine Transport by Atb0

Catalysed by STS, SLC26A6, SLC6A14cytosol, extracellular spaceOne of 5 routes

1. Estrone 3-sulfate sulfohydrolase
2. L-aspartate(in) + sulfate(out) = L-aspartate(out) + sulfate(in)
3. acetyl-CoA:L-aspartate N-acetyltransferase

Catalysed by STS