Compound
prostaglandin G2
A prostaglandin carboxylic acid anion that is the conjugate base of prostaglandin G2, obtained by deprotonation of the carboxy group; major species at pH 7.3.
Definition from ChEBI (CHEBI:82629), read 2026-09-23. CC BY 4.0.
Structure
- Class
- Organic compound, anion
- Formula
- C20H31O6
- Mass
- 367.462 g/mol
- Charge
- -1
- InChIKey
- SGUKUZOVHSFKPH-YNNPMVKQSA-M
- SMILES
- CCCCC[C@@H](/C=C/[C@@H]1[C@@H](C/C=CCCCC(=O)[O-])[C@@H]2C[C@H]1OO2)OO
- Look it up
- ChEBIBy InChIKey
Identity from ChEBI. Not evidence.
What it touches on the way
Mechanistic reach
5 entities
5 entities reached.
0 reported hops5 assembled from the scaffold
- PTGS2ProteinUNIPROT:P35354substrate ofInferred only168 paths56 endpoints
- PTGS1ProteinUNIPROT:P23219substrate ofInferred only66 paths22 endpoints
- SLCO2A1ProteinUNIPROT:Q92959transported byInferred only14 paths13 endpoints
- PTGESProteinUNIPROT:O14684substrate ofInferred only13 paths13 endpoints
- SLCO1B1ProteinUNIPROT:Q9Y6L6transported byInferred only9 paths2 endpoints
What the reference databases state
Statements
18 statements
18 statements · 2 reference databases · Subject: prostaglandin G2 · Sources: Human-GEM, Rhea
- (15S)-15-hydroperoxy-prostaglandin E2 is converted to prostaglandin G2CompoundRhea RHEA:64364Inferred only
- prostaglandin G2 is converted to (15S)-15-hydroperoxy-prostaglandin E2CompoundRhea RHEA:64364Inferred only
- prostaglandin G2 is converted to (5Z,8Z,11Z,14Z)-eicosatetraenoateCompoundRhea RHEA:42596Inferred only
- (5Z,8Z,11Z,14Z)-eicosatetraenoate is converted to prostaglandin G2CompoundHuman-GEM MAR01305Inferred only
- (5Z,8Z,11Z,14Z)-eicosatetraenoate is converted to prostaglandin G2CompoundRhea RHEA:42596Inferred only
- prostaglandin G2 is converted to prostaglandin H2CompoundHuman-GEM MAR01307Inferred only
- prostaglandin G2 is a substrate of PTGESProteinRhea RHEA:64364Inferred only
- prostaglandin G2 is a substrate of PTGS1ProteinRhea RHEA:42600Inferred only
- prostaglandin G2 is a substrate of PTGS1ProteinRhea RHEA:42596Inferred only
- prostaglandin G2 is a substrate of PTGS1ProteinHuman-GEM MAR01307Inferred only
- prostaglandin G2 is a substrate of PTGS2ProteinHuman-GEM MAR01307Inferred only
- prostaglandin G2 is a substrate of PTGS2ProteinRhea RHEA:42596Inferred only
Show the remaining 6
- prostaglandin G2 is a substrate of PTGS2ProteinRhea RHEA:42600Inferred only
- prostaglandin G2 is transported by SLC22A10ProteinHuman-GEM MAR06272Inferred only
- prostaglandin G2 is transported by SLCO1B1ProteinHuman-GEM MAR06206Inferred only
- prostaglandin G2 is transported by SLCO1B1ProteinHuman-GEM MAR06205Inferred only
- prostaglandin G2 is transported by SLCO1B1ProteinHuman-GEM MAR06207Inferred only
- prostaglandin G2 is transported by SLCO2A1ProteinHuman-GEM MAR06238Inferred only
Reactions
12 reactions
(5Z,8Z,11Z,14Z)-eicosatetraenoate+2dioxygenprostaglandin G2
Reaction pageLeft to rightBalancedEC 1.14.99.1GO:0005783
Human-GEM MAR01305CC BY 4.0Reference data
prostaglandin G2prostaglandin G2
Reaction pageReversibleBalancedGO:0005829, GO:0005783
Human-GEM MAR01306CC BY 4.0Reference data
2proton+prostaglandin G2water+prostaglandin H2
Reaction pageLeft to rightUnbalancedEC 1.14.99.1GO:0005783
Human-GEM MAR01307CC BY 4.0Reference data
Reaction pageReversibleBalance undeterminableGO:0005615
Human-GEM MAR04238CC BY 4.0Reference data
MAM01980c+hydrogencarbonate+prostaglandin G2MAM01980e+hydrogencarbonate+prostaglandin G2
Transported by SLCO1B1
Reaction pageReversibleBalance undeterminableGO:0005829, GO:0005615
Human-GEM MAR06205CC BY 4.0Reference data
hydrogencarbonate+prostaglandin G2+2,4-dinitrophenyl-S-glutathionehydrogencarbonate+prostaglandin G2+2,4-dinitrophenyl-S-glutathione
Transported by SLCO1B1
Reaction pageReversibleBalancedGO:0005829, GO:0005615
Human-GEM MAR06206CC BY 4.0Reference data
hydrogencarbonate+prostaglandin G2+MAM02901chydrogencarbonate+prostaglandin G2+MAM02901e
Transported by SLCO1B1
Reaction pageReversibleBalancedGO:0005829, GO:0005615
Human-GEM MAR06207CC BY 4.0Reference data
CHEBI:16856+hydrogencarbonate+prostaglandin G2CHEBI:16856+hydrogencarbonate+prostaglandin G2
Transported by SLCO2A1
Reaction pageReversibleBalancedGO:0005829, GO:0005615
Human-GEM MAR06238CC BY 4.0Reference data
prostaglandin G2prostaglandin G2
Transported by SLC22A10
Reaction pageReversibleBalancedGO:0005829, GO:0005615
Human-GEM MAR06272CC BY 4.0Reference data
(5Z,8Z,11Z,14Z)-eicosatetraenoate+2dioxygenprostaglandin G2
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:42596CC BY 4.0Reference data
prostaglandin G2+AH2prostaglandin H2+A+water
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:42600CC BY 4.0Reference data
prostaglandin G2(15S)-15-hydroperoxy-prostaglandin E2
Catalysed by PTGES
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:64364CC BY 4.0Reference data
Where it reaches
5 systems, 8 regions, 15 tissues, 15 transporter routes — routes, not measurements: transporters known to carry prostaglandin G2 are expressed there, and no source reports it arriving.
Loading the model…
Other names
3 names
Resolves to: prostaglandin G2
- Also called
- PGG2
- Systematic name
- (5Z,9S,11R,13E,15S)-15-hydroperoxy-9,11-epidioxyprosta-5,13-dien-1-oate(5Z)-7-{(1R,4S,5R,6R)-6-[(1E,3S)-3-hydroperoxyoct-1-en-1-yl]-2,3-dioxabicyclo[2.2.1]hept-5-yl}hept-5-enoate