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pentanal

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

Inferred

Every route here is a hypothesis drawn from reference reactions (Rhea and Human-GEM), not a finding. Currency species such as water, ATP and NAD(H) never form a step. Evidence key

11 compounds within 3 steps: 1 in 1, 2 in 2, 8 in 3

Does it reach a compound?

One step

pentanoateReach from here →
1. pentanal + NAD(+) + H2O = pentanoate + NADH + 2 H(+)
Catalysed by ALDH9A1

Two steps

dehydroepiandrosterone 3-sulfateReach from here →
1. pentanal + NAD(+) + H2O = pentanoate + NADH + 2 H(+)
2. pentanoate(out) + dehydroepiandrosterone 3-sulfate(in) = pentanoate(in) + dehydroepiandrosterone 3-sulfate(out)
Catalysed by ALDH9A1, SLC22A9inner side of the membrane, outer side of the membraneOne of 2 routes
estrone 3-sulfateReach from here →
1. pentanal + NAD(+) + H2O = pentanoate + NADH + 2 H(+)
2. pentanoate(in) + estrone 3-sulfate(out) = pentanoate(out) + estrone 3-sulfate(in)
Catalysed by ALDH9A1, SLC22A9inner side of the membrane, outer side of the membraneOne of 2 routes

Three steps

2,4-dinitrophenyl-S-glutathioneReach from here →
Catalysed by ALDH9A1, SLC22A9, SLCO1B1inner side of the membrane, outer side of the membrane, extracellular space, cytosolOne of 4 routes
sulfateReach from here →

Catalysed by ALDH9A1, SLC22A9, STS

inner side of the membrane, outer side of the membrane, cytosol

One of 6 routes

estroneReach from here →

pentanal + NAD(+) + H2O = pentanoate + NADH + 2 H(+)
pentanoate(in) + estrone 3-sulfate(out) = pentanoate(out) + estrone 3-sulfate(in)
Estrone 3-sulfate sulfohydrolase

Catalysed by ALDH9A1, SLC22A9, STSinner side of the membrane, outer side of the membrane, cytosolOne of 3 routes

propanoateReach from here →

pentanal + NAD(+) + H2O = pentanoate + NADH + 2 H(+)
pentanoate(in) + estrone 3-sulfate(out) = pentanoate(out) + estrone 3-sulfate(in)
propanoate(in) + estrone 3-sulfate(out) = propanoate(out) + estrone 3-sulfate(in)

Catalysed by ALDH9A1, SLC22A9inner side of the membrane, outer side of the membraneOne of 4 routes

butanoateReach from here →

pentanal + NAD(+) + H2O = pentanoate + NADH + 2 H(+)
pentanoate(in) + estrone 3-sulfate(out) = pentanoate(out) + estrone 3-sulfate(in)
butanoate(out) + estrone 3-sulfate(in) = butanoate(in) + estrone 3-sulfate(out)

Catalysed by ALDH9A1, SLC22A9inner side of the membrane, outer side of the membraneOne of 4 routes

3beta-hydroxyandrost-5-en-17-oneReach from here →

pentanal + NAD(+) + H2O = pentanoate + NADH + 2 H(+)
pentanoate(out) + dehydroepiandrosterone 3-sulfate(in) = pentanoate(in) + dehydroepiandrosterone 3-sulfate(out)
3beta-Hydroxyandrost-5-en-17-one 3-sulfate sulfohydrolase

Catalysed by ALDH9A1, SLC22A9, STSinner side of the membrane, outer side of the membrane, cytosolOne of 3 routes

glutarateReach from here →

pentanal + NAD(+) + H2O = pentanoate + NADH + 2 H(+)
pentanoate(in) + estrone 3-sulfate(out) = pentanoate(out) + estrone 3-sulfate(in)
estrone 3-sulfate(out) + glutarate(in) = estrone 3-sulfate(in) + glutarate(out)

Catalysed by ALDH9A1, SLC22A9, SLC22A24, SLC22A8 and 1 moreinner side of the membrane, outer side of the membraneOne of 4 routes

16alpha-hydroxydehydroepiandrosterone 3-sulfateReach from here →

pentanal + NAD(+) + H2O = pentanoate + NADH + 2 H(+)
pentanoate(out) + dehydroepiandrosterone 3-sulfate(in) = pentanoate(in) + dehydroepiandrosterone 3-sulfate(out)
dehydroepiandrosterone 3-sulfate + reduced [NADPH--hemoprotein reductase] + O2 = 16alpha-hydroxydehydroepiandrosterone 3-sulfate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Catalysed by ALDH9A1, SLC22A9, CYP3A7inner side of the membrane, outer side of the membrane