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Proteins/UNIPROT:Q53FZ2
Catalyzes the activation of fatty acids by CoA to produce an acyl-CoA, the first step in fatty acid metabolism. Capable of activating medium-chain fatty acids with a preference for isobutyrate among fatty acids with 2-6 carbon atoms (By similarity)..
Function from UniProtKB (Q53FZ2), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
37 statements
37 statements · 7 reference databases · Subject: ACSM3 · Sources: Bgee, gene ontology, Hetionet, Human-GEM, Reactome, Rhea, UniProt
14 reactions
ATP+butyric acid+CHEBI:1146900AMP+butanoyl-CoA+diphosphate(3-)
Catalysed by ACSM3 or ACSM2B or ACSM1 or ACSM5 or ACSM2A or ACSM4
Reaction pageLeft to rightBalancedEC 6.2.1.2cytosol
Human-GEM MAR00156CC BY 4.0Reference data
ATP+
8 names
Resolves to: ACSM3
Reaction pageLeft to rightBalancedEC 6.2.1.2cytosol
Human-GEM MAR00165CC BY 4.0Reference data
ATP+CHEBI:1146900+MAM02120cAMP+CHEBI:27540+diphosphate(3-)
Catalysed by ACSM3 or ACSM2B or ACSM1 or ACSM5 or ACSM2A or ACSM4
Reaction pageLeft to rightBalancedEC 6.2.1.2cytosol
Human-GEM MAR00168CC BY 4.0Reference data
ATP+CHEBI:1146900+heptanoateAMP+MAM02107c+diphosphate(3-)
Catalysed by ACSM3 or ACSM2B or ACSM1 or ACSM5 or ACSM2A or ACSM4
Reaction pageLeft to rightBalancedEC 6.2.1.2cytosol
Human-GEM MAR00171CC BY 4.0Reference data
ATP+CHEBI:1146900+octanoateAMP+octanoyl-CoA+diphosphate(3-)
Catalysed by ACSM3 or ACSM2B or ACSM1 or ACSM5 or ACSM2A or ACSM4
Reaction pageLeft to rightBalancedEC 6.2.1.2cytosol
Human-GEM MAR00174CC BY 4.0Reference data
ATP+CHEBI:1146900+nonanoateAMP+MAM02616c+diphosphate(3-)
Catalysed by ACSM3 or ACSM2B or ACSM1 or ACSM5 or ACSM2A or ACSM4
Reaction pageLeft to rightBalancedEC 6.2.1.2cytosol
Human-GEM MAR00177CC BY 4.0Reference data
ATP+CHEBI:1146900+decanoateAMP+decanoyl-CoA+diphosphate(3-)
Catalysed by ACSM3 or ACSM2B or ACSM1 or ACSM5 or ACSM2A or ACSM4
Reaction pageLeft to rightBalancedEC 6.2.1.2cytosol
Human-GEM MAR00180CC BY 4.0Reference data
ATP+CHEBI:1146900+MAM03117cAMP+diphosphate(3-)+undecanoyl-CoA
Catalysed by ACSM3 or ACSM2B or ACSM1 or ACSM5 or ACSM2A or ACSM4
Reaction pageLeft to rightBalancedEC 6.2.1.2cytosol
Human-GEM MAR00184CC BY 4.0Reference data
propanoate+ATP(4-)+coenzyme A(4-)propanoyl-CoA+AMP+diphosphate(3-)
Catalysed by ACSM3 or ACSS3 or ACSS2 or ACSS1
Reaction pageLeft to rightBalanced
Rhea RHEA:20373CC BY 4.0Reference data
octanoate+ATP(4-)+coenzyme A(4-)octanoyl-CoA+AMP+diphosphate(3-)
Catalysed by ACSM4 or ACSM1 or ACSM2A or ACSM3 or ACSM2B or ACSF2
Reaction pageLeft to rightBalanced
Rhea RHEA:33631CC BY 4.0Reference data
butanoate+ATP(4-)+coenzyme A(4-)butanoyl-CoA+AMP+diphosphate(3-)
Catalysed by ACSM1 or ACSM2A or ACSM3 or ACSM2B or ACSS3
Reaction pageLeft to rightBalanced
Rhea RHEA:46172CC BY 4.0Reference data
2-methylpropanoate+ATP(4-)+coenzyme A(4-)2-methylpropanoyl-CoA+AMP+diphosphate(3-)
Catalysed by ACSM3
Reaction pageLeft to rightBalanced
Rhea RHEA:46176CC BY 4.0Reference data