20-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

241 compounds within 3 steps: 4 in 1, 53 in 2, 184 in 3

One step

2,4-dinitrophenyl-S-glutathioneReach from here →
1. Resistance-Nodulation-Cell Division (Rnd) Tcdb:2.A.60.1.5
Catalysed by SLCO1B1extracellular space, cytosolOne of 2 routes
CHEBI:16856Reach from here →
1. Resistance-Nodulation-Cell Division (Rnd) Tcdb:2.A.60.1.2
Catalysed by SLCO2A1extracellular space, cytosolOne of 2 routes
20-O-(beta-D-glucuronosyl)-(5Z,8Z,11Z,14Z)-eicosatetraenoateReach from here →
1. 20-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + UDP-alpha-D-glucuronate = 20-O-(beta-D-glucuronosyl)-(5Z,8Z,11Z,14Z)-eicosatetraenoate + UDP + H(+)
Catalysed by UGT2B7, UGT1A1, UGT1A4
20-oxo-(5Z,8Z,11Z,14Z)-eicosatetraenoateReach from here →
1. 10-HETE[n] + NAD+[n] = H+[n] + NADH[n] + 20-oxo-(5Z,8Z,11Z,14Z)-eicosatetraenoate[n]
Catalysed by ADH4nucleusOne of 3 routes

Two steps

tauroursodeoxycholateReach from here →
1. Resistance-Nodulation-Cell Division (Rnd) Tcdb:2.A.60.1.5
2. transport of S-glutathionyl-2-4-dinitrobenzene (cytosol to extracellular)
Catalysed by SLCO1B1, SLCO1A2, SLCO1B3extracellular space, cytosolOne of 4 routes
glycoursodeoxycholateReach from here →
1. Resistance-Nodulation-Cell Division (Rnd) Tcdb:2.A.60.1.5
2. transport of glycoursodeoxycholate (cytosol to extracellular)
Catalysed by SLCO1B1, SLCO1A2, SLCO1B3extracellular space, cytosol

One of 4 routes

(11S,15S)-dihydroxy-14(R)-S-glutathionyl-(5Z,8Z,12E)-eicosatrienoateReach from here →

Catalysed by SLCO2A1, PTGES, MGST3, GSTA4 and 18 moreextracellular space, cytosolOne of 4 routes

prostaglandin E3Reach from here →

Catalysed by SLCO1B1extracellular space, cytosolOne of 4 routes

prostaglandin A2Reach from here →

Catalysed by SLCO1B1extracellular space, cytosolOne of 4 routes

prostaglandin B1Reach from here →

Catalysed by SLCO1B1extracellular space, cytosolOne of 4 routes

leukotriene F4Reach from here →

Catalysed by SLCO1B1extracellular space, cytosolOne of 4 routes

acetylcholineReach from here →

Catalysed by SLCO1B1, SLCO1B3extracellular space, cytosolOne of 4 routes

CHEBI:15650Reach from here →

Catalysed by SLCO1B1extracellular space, cytosolOne of 4 routes

bromideReach from here →

Catalysed by SLCO2A1, MGST3, GSTA4, GSTA1 and 14 moreextracellular space, cytosolOne of 2 routes

lithocholic acidReach from here →

Catalysed by SLCO1B1, SLCO1A2, SLCO1B3extracellular space, cytosolOne of 4 routes

bilirubin IXalphaReach from here →

Catalysed by SLCO1B1, SLCO1A2, SLCO1B3extracellular space, cytosolOne of 4 routes

taurolithocholateReach from here →

Catalysed by SLCO1B1, SLCO1A2, SLCO1B3extracellular space, cytosolOne of 4 routes

CHEBI:17208Reach from here →

Catalysed by SLCO2A1extracellular space, cytosol

homocysteineReach from here →

Catalysed by SLCO2A1extracellular space, cytosol

L-cysteineReach from here →

Catalysed by SLCO2A1extracellular space, cytosol

5(S)-HETEReach from here →

Catalysed by SLCO2A1, GPX5, GPX1, GPX2 and 6 moreextracellular space, cytosolOne of 2 routes

CHEBI:28666Reach from here →

Catalysed by SLCO1B1extracellular space, cytosolOne of 4 routes

glycocholateReach from here →

Catalysed by SLCO1B1, SLCO1A2, SLCO1B3extracellular space, cytosolOne of 4 routes

cholateReach from here →

Catalysed by SLCO1B1, SLCO1A2, SLCO1B3extracellular space, cytosolOne of 4 routes

(5Z,8Z,11Z,14Z)-eicosatetraenoateReach from here →

Catalysed by SLCO1B1extracellular space, cytosolOne of 4 routes

serotoninReach from here →

Catalysed by SLCO1B1, SLCO1A2, SLCO1B3extracellular space, cytosolOne of 4 routes

chenodeoxycholateReach from here →

Catalysed by SLCO1B1, SLCO1A2, SLCO1B3extracellular space, cytosolOne of 2 routes

taurocholateReach from here →

Catalysed by SLCO1B1, SLCO1A2, SLCO1B3extracellular space, cytosolOne of 4 routes

glycolithocholic acidReach from here →

Catalysed by SLCO1B1, SLCO1A2, SLCO1B3extracellular space, cytosolOne of 4 routes

gamma-Glu-AlaReach from here →

Catalysed by SLCO2A1, GGT1, GGT5, GGTLC2 and 3 moreextracellular space, cytosol

3,3',5-triiodo-L-thyronineReach from here →

Catalysed by SLCO1B1, SLCO1A2, SLCO1B3extracellular space, cytosolOne of 4 routes

prostaglandin E1Reach from here →

Catalysed by SLCO1B1extracellular space, cytosolOne of 4 routes

prostaglandin I2Reach from here →

Catalysed by SLCO1B1extracellular space, cytosolOne of 4 routes

prostaglandin F2alphaReach from here →

Catalysed by SLCO1B1extracellular space, cytosolOne of 4 routes

prostaglandin H2Reach from here →

Catalysed by SLCO1B1extracellular space, cytosolOne of 4 routes

prostaglandin D2Reach from here →

Catalysed by SLCO1B1extracellular space, cytosolOne of 4 routes

(15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoateReach from here →

Catalysed by SLCO2A1, GPX5, GPX1, GPX2 and 6 moreextracellular space, cytosol

leukotriene A4Reach from here →

Catalysed by SLCO1B1extracellular space, cytosolOne of 4 routes

(R)-S-lactoylglutathioneReach from here →

Catalysed by SLCO2A1, GLO1, GLOD4extracellular space, cytosolOne of 2 routes

S-formylglutathioneReach from here →

Catalysed by SLCO2A1, ADH1C, ADH1A, ADH5 and 3 moreextracellular space, cytosol

dehydroepiandrosterone 3-sulfateReach from here →

Catalysed by SLCO1B1extracellular space, cytosolOne of 2 routes

leukotriene C4Reach from here →

Catalysed by SLCO1B1extracellular space, cytosolOne of 6 routes

glutathione disulfideReach from here →

Catalysed by SLCO2A1, GPX5, GPX1, GPX2 and 6 moreextracellular space, cytosolOne of 13 routes

taurolithocholate 3-sulfateReach from here →

Catalysed by SLCO1B1, SLCO1A2, SLCO1B3extracellular space, cytosolOne of 4 routes

histamineReach from here →

Catalysed by SLCO1B1, SLCO1A2, SLCO1B3extracellular space, cytosolOne of 4 routes

L-thyroxineReach from here →

Catalysed by SLCO1B1, SLCO1A2, SLCO1B3extracellular space, cytosolOne of 4 routes

S-sulfanylglutathioneReach from here →

Catalysed by SLCO2A1, SQORextracellular space, cytosol, mitochondrial matrix

dopamineReach from here →

Catalysed by SLCO1B1, SLCO1A2, SLCO1B3extracellular space, cytosolOne of 4 routes

glycolithocholate 3-sulfateReach from here →

Catalysed by SLCO1B1, SLCO1A2, SLCO1B3extracellular space, cytosolOne of 4 routes

estrone 3-sulfateReach from here →

Catalysed by SLCO1B1extracellular space, cytosolOne of 2 routes