Compound
glycolithocholate 3-sulfate
A steroid sulfate oxoanion and N-acylglycinate that is the dianion of sulfoglycolithocholic acid arising from deprotonation of carboxylic acid and sulfate functions; major species at pH 7.3.
Definition from ChEBI (CHEBI:60007), read 2026-09-23. CC BY 4.0.
Structure
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- Class
- Organic compound, anion
- Formula
- C26H41NO7S
- Mass
- 511.681 g/mol
- Charge
- -2
- InChIKey
- FHXBAFXQVZOILS-OETIFKLTSA-L
- SMILES
- [H][C@]12CC[C@]3([H])[C@]([H])(CC[C@@]4(C)[C@@]3([H])CC[C@]4([H])[C@H](C)CCC(=O)NCC(=O)[O-])[C@@]1(C)CC[C@@H](OS(=O)(=O)[O-])C2
- Look it up
- ChEBIPubChemBy InChIKey
Identity from ChEBI, geometry from PubChem. Not evidence.
What it touches on the way
Mechanistic reach
3 entities
3 entities reached.
What the reference databases state
Statements
11 statements
11 statements · 2 reference databases · Subject: glycolithocholate 3-sulfate · Sources: Human-GEM, Rhea
- glycolithocholic acid is converted to glycolithocholate 3-sulfateCompoundHuman-GEM MAR01846Inferred only
- glycolithocholate 3-sulfate is metabolised by SULT2A1ProteinRhea RHEA:10908Inferred only
- glycolithocholate 3-sulfate is a substrate of STSProteinHuman-GEM MAR01847Inferred only
- glycolithocholate 3-sulfate is transported by SLCO1A2ProteinHuman-GEM MAR06088Inferred only
- glycolithocholate 3-sulfate is transported by SLCO1A2ProteinHuman-GEM MAR06066Inferred only
- glycolithocholate 3-sulfate is transported by SLCO1A2ProteinHuman-GEM MAR06086Inferred only
- glycolithocholate 3-sulfate is transported by SLCO1A2ProteinHuman-GEM MAR06087Inferred only
- glycolithocholate 3-sulfate is transported by SLCO1B3ProteinHuman-GEM MAR06087Inferred only
- glycolithocholate 3-sulfate is transported by SLCO1B3ProteinHuman-GEM MAR06086Inferred only
- glycolithocholate 3-sulfate is transported by SLCO1B3ProteinHuman-GEM MAR06088Inferred only
- glycolithocholate 3-sulfate is transported by SLCO1B3ProteinHuman-GEM MAR06066Inferred only
Reactions
8 reactions
glycolithocholic acid+3'-phospho-5'-adenylyl sulfateproton+adenosine 3',5'-bismonophosphate+glycolithocholate 3-sulfate
Catalysed by SULT2A1
Reaction pageLeft to rightBalancedEC 2.8.2.14GO:0005829
Human-GEM MAR01846CC BY 4.0Reference data
water+glycolithocholate 3-sulfateglycolithocholic acid+proton+sulfate
Catalysed by STS
Reaction pageLeft to rightBalancedEC 3.1.6.2GO:0005829
Human-GEM MAR01847CC BY 4.0Reference data
Reaction pageReversibleBalance undeterminableGO:0005615
Human-GEM MAR04178CC BY 4.0Reference data
CHEBI:16856+hydrogencarbonate+glycolithocholate 3-sulfateCHEBI:16856+hydrogencarbonate+glycolithocholate 3-sulfate
Transported by SLCO1A2 & SLCO1B3
Reaction pageReversibleBalancedGO:0005829, GO:0005615
Human-GEM MAR06066CC BY 4.0Reference data
MAM01980c+hydrogencarbonate+glycolithocholate 3-sulfateMAM01980e+hydrogencarbonate+glycolithocholate 3-sulfate
Transported by SLCO1A2 & SLCO1B3
Reaction pageReversibleBalance undeterminableGO:0005829, GO:0005615
Human-GEM MAR06086CC BY 4.0Reference data
hydrogencarbonate+2,4-dinitrophenyl-S-glutathione+glycolithocholate 3-sulfatehydrogencarbonate+2,4-dinitrophenyl-S-glutathione+glycolithocholate 3-sulfate
Transported by SLCO1A2 & SLCO1B3
Reaction pageReversibleBalancedGO:0005829, GO:0005615
Human-GEM MAR06087CC BY 4.0Reference data
hydrogencarbonate+MAM02901c+glycolithocholate 3-sulfatehydrogencarbonate+MAM02901e+glycolithocholate 3-sulfate
Transported by SLCO1A2 & SLCO1B3
Reaction pageReversibleBalancedGO:0005829, GO:0005615
Human-GEM MAR06088CC BY 4.0Reference data
glycolithocholate+3'-phosphoadenylyl sulfateglycolithocholate 3-sulfate+adenosine 3',5'-bisphosphate+hydron
Catalysed by SULT2A1
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:10908CC BY 4.0Reference data
Where it reaches
1 system, 1 region, 2 tissues, 2 transporter routes — routes, not measurements: transporters known to carry glycolithocholate 3-sulfate are expressed there, and no source reports it arriving.
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Other names
3 names
Resolves to: glycolithocholate 3-sulfate
- Also called
- glycolithocholate sulfate
- Systematic name
- N-[3alpha-(sulfonatooxy)-5beta-cholan-24-oyl]glycinateN-[3α-(sulfonatooxy)-5β-cholan-24-oyl]glycinate