Compound
4-hydroxyestrone
No description recorded for this entry yet. Everything this graph holds about 4-hydroxyestrone is below.
Structure
- Class
- Organic compound
- Formula
- C18H22O3
- Mass
- 286.371 g/mol
- Charge
- 0
- InChIKey
- XQZVQQZZOVBNLU-QDTBLXIISA-N
- SMILES
- [H][C@@]12CCC(=O)[C@@]1(C)CC[C@]1([H])c3ccc(O)c(O)c3CC[C@@]21[H]
- Look it up
- ChEBIBy InChIKey
Identity from ChEBI. Not evidence — none of it carries a grade.
What it touches on the way
A finding says 4-hydroxyestrone moved an endpoint. This is the biology in between: the proteins and reactions it runs through to get there. It is where to look for the two things a list of findings cannot answer — why a result might happen, and what else acts on the same machinery.
10 of these are proteins with a page of their own, and that is the door: a protein page says what else it carries, which is how one compound leads to the next.
Mechanistic reach
10 entities
10 entities reached, most connected first. Hub metabolites are excluded, so this is not a claim that the compound touches everything.
0 reported hops10 assembled from the scaffold
- CYP3A4ProteinUNIPROT:P08684metabolized byInferred only48 paths48 endpoints
- CYP1A2ProteinUNIPROT:P05177metabolized byInferred only38 paths38 endpoints
- CYP1A1ProteinUNIPROT:P04798metabolized byInferred only32 paths32 endpoints
- CYP1B1ProteinUNIPROT:Q16678metabolized byInferred only29 paths29 endpoints
- COMTProteinUNIPROT:P21964metabolized byInferred only26 paths26 endpoints
- UGT1A9ProteinUNIPROT:O60656metabolized byInferred only24 paths24 endpoints
- UGT1A8ProteinUNIPROT:Q9HAW9metabolized byInferred only22 paths11 endpoints
- UGT2B7ProteinUNIPROT:P16662metabolized byInferred only16 paths16 endpoints
- CYP3A5ProteinUNIPROT:P20815metabolized byInferred only15 paths15 endpoints
- CYP3A7ProteinUNIPROT:P24462metabolized byInferred only13 paths13 endpoints
What the reference databases state
The section above shows paths a projection assembled. This is the reference layer itself, one step from 4-hydroxyestrone: what the cleared databases state it reacts with, is carried by, is converted to and takes part in, whether or not a projection has walked it yet.
Statements
11 statements
11 statements in 1 reference database name 4-hydroxyestrone — Rhea. Press a relation to see only its rows; every count is the rows behind it.
- 4-hydroxyestrone is metabolised by COMTProteinRhea RHEA:53104Inferred only
- 4-hydroxyestrone is metabolised by CYP1A1ProteinRhea RHEA:47292Inferred only
- 4-hydroxyestrone is metabolised by CYP1A2ProteinRhea RHEA:47292Inferred only
- 4-hydroxyestrone is metabolised by CYP1B1ProteinRhea RHEA:47292Inferred only
- 4-hydroxyestrone is metabolised by CYP3A4ProteinRhea RHEA:47292Inferred only
- 4-hydroxyestrone is metabolised by CYP3A5ProteinRhea RHEA:47292Inferred only
- 4-hydroxyestrone is metabolised by CYP3A7ProteinRhea RHEA:47292Inferred only
- 4-hydroxyestrone is metabolised by UGT1A8ProteinRhea RHEA:53052Inferred only
- 4-hydroxyestrone is metabolised by UGT1A8ProteinRhea RHEA:53060Inferred only
- 4-hydroxyestrone is metabolised by UGT1A9ProteinRhea RHEA:53060Inferred only
- 4-hydroxyestrone is metabolised by UGT2B7ProteinRhea RHEA:53060Inferred only
Other names
5 names
Every name this graph resolves to 4-hydroxyestrone. Searching any of them lands here.
- Also called
- 3,4-dihydroxy-1,3,5(10)-estratrien-17-one3,4-dihydroxy-estra-1,3,5(10)-trien-17-oneestra-1,3,5(10)-triene-3,4-diol-17-oneST 18:4;O3
- Systematic name
- 3,4-dihydroxyestra-1,3,5(10)-trien-17-one