Compound
glycolithocholic acid
The glycine conjugate of lithocholic acid.
Definition from ChEBI (CHEBI:37998), read 2026-09-23. CC BY 4.0.
What it touches on the way
Mechanistic reach
4 entities
4 entities reached.
0 reported hops4 assembled from the scaffold
What the reference databases state
Chemical structure
- glycolithocholic acid has the functional parent lithocholic acidCompoundChEBI CHEBI:37998Inferred only
Statements
12 statements
12 statements · 1 reference database · Subject: glycolithocholic acid · Sources: Human-GEM
- glycolithocholic acid is converted to glycolithocholate 3-sulfateCompoundHuman-GEM MAR01846Inferred only
- glycolithocholic acid is metabolised by SULT2A1ProteinHuman-GEM MAR01846Inferred only
- glycolithocholic acid is transported by SLC10A1ProteinHuman-GEM MAR05436Inferred only
- glycolithocholic acid is transported by SLC10A2ProteinHuman-GEM MAR05436Inferred only
- glycolithocholic acid is transported by SLCO1A2ProteinHuman-GEM MAR06074Inferred only
- glycolithocholic acid is transported by SLCO1A2ProteinHuman-GEM MAR06075Inferred only
- glycolithocholic acid is transported by SLCO1A2ProteinHuman-GEM MAR06062Inferred only
- glycolithocholic acid is transported by SLCO1A2ProteinHuman-GEM MAR06076Inferred only
- glycolithocholic acid is transported by SLCO1B3ProteinHuman-GEM MAR06062Inferred only
- glycolithocholic acid is transported by SLCO1B3ProteinHuman-GEM MAR06076Inferred only
- glycolithocholic acid is transported by SLCO1B3ProteinHuman-GEM MAR06074Inferred only
- glycolithocholic acid is transported by SLCO1B3ProteinHuman-GEM MAR06075Inferred only
Reactions
10 reactions
ATP+glycine+lithocholic acidAMP+glycolithocholic acid+proton+diphosphate(3-)
Catalysed by BAAT
Reaction pageLeft to rightBalancedEC 6.2.1.-, 2.3.1.65GO:0005829
Human-GEM MAR01844CC BY 4.0Reference data
ATP+glycine+lithocholic acidAMP+glycolithocholic acid+proton+diphosphate(3-)
Catalysed by BAAT
Reaction pageLeft to rightBalancedEC 6.2.1.-, 2.3.1.65GO:0005777
Human-GEM MAR01845CC BY 4.0Reference data
glycolithocholic acid+3'-phospho-5'-adenylyl sulfateproton+adenosine 3',5'-bismonophosphate+glycolithocholate 3-sulfate
Catalysed by SULT2A1
Reaction pageLeft to rightBalancedEC 2.8.2.14GO:0005829
Human-GEM MAR01846CC BY 4.0Reference data
water+glycolithocholate 3-sulfateglycolithocholic acid+proton+sulfate
Catalysed by STS
Reaction pageLeft to rightBalancedEC 3.1.6.2GO:0005829
Human-GEM MAR01847CC BY 4.0Reference data
Reaction pageReversibleBalance undeterminableGO:0005615
Human-GEM MAR04148CC BY 4.0Reference data
glycolithocholic acid+2sodium(1+)glycolithocholic acid+2sodium(1+)
Transported by SLC10A1 or SLC10A2
Reaction pageLeft to rightBalancedGO:0005615, GO:0005829
Human-GEM MAR05436CC BY 4.0Reference data
glycolithocholic acid+CHEBI:16856+hydrogencarbonateglycolithocholic acid+CHEBI:16856+hydrogencarbonate
Transported by SLCO1A2 & SLCO1B3
Reaction pageReversibleBalancedGO:0005615, GO:0005829
Human-GEM MAR06062CC BY 4.0Reference data
MAM01980c+glycolithocholic acid+hydrogencarbonateMAM01980e+glycolithocholic acid+hydrogencarbonate
Transported by SLCO1A2 & SLCO1B3
Reaction pageReversibleBalance undeterminableGO:0005829, GO:0005615
Human-GEM MAR06074CC BY 4.0Reference data
glycolithocholic acid+hydrogencarbonate+2,4-dinitrophenyl-S-glutathioneglycolithocholic acid+hydrogencarbonate+2,4-dinitrophenyl-S-glutathione
Transported by SLCO1A2 & SLCO1B3
Reaction pageReversibleBalancedGO:0005615, GO:0005829
Human-GEM MAR06075CC BY 4.0Reference data
glycolithocholic acid+hydrogencarbonate+MAM02901cglycolithocholic acid+hydrogencarbonate+MAM02901e
Transported by SLCO1A2 & SLCO1B3
Reaction pageReversibleBalancedGO:0005615, GO:0005829
Human-GEM MAR06076CC BY 4.0Reference data
Where it reaches
1 system, 2 regions, 3 tissues, 4 transporter routes — routes, not measurements: transporters known to carry glycolithocholic acid are expressed there, and no source reports it arriving.
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Other names
6 names
Resolves to: glycolithocholic acid
- Also called
- GlycolithocholateLithocholic acid glycine conjugateLithocholylglycineN-((3-alpha,5-beta)-3-Hydroxy-24-oxocholan-24-yl)glycine
- Systematic name
- N-(3alpha-hydroxy-5beta-cholan-24-oyl)glycineN-(3α-hydroxy-5β-cholan-24-oyl)glycine