(R)-noradrenaline

1. transport of noradrenaline (cytosol to extracellular)

Catalysed by SLCO1A2, SLCO1B3extracellular space, cytosolOne of 2 routes

1. transport of GSH and noradrenaline (cytosol to extracellular)

Catalysed by SLCO1A2, SLCO1B3extracellular space, cytosolOne of 2 routes

1. (R)-noradrenaline + O2 + H2O = (R)-3,4-dihydroxymandelaldehyde + H2O2 + NH4(+)

Catalysed by MAOA, MAOB

1. S-Adenosyl-L-methionine:catechol O-methyltransferase

Catalysed by COMT, LRTOMTcytosol

1. sulfotransferase (noradrenaline)

Catalysed by SULT1A3cytosolOne of 2 routes

1. S-Adenosyl-L-methionine:phenylethanolamine N-methyltransferase

Catalysed by PNMTcytosol

1. (R)-noradrenaline + S-adenosyl-L-methionine = (R)-adrenaline + S-adenosyl-L-homocysteine + H(+)

Catalysed by PNMT

1. transport of noradrenaline (cytosol to extracellular)
2. transport of S-glutathionyl-2-4-dinitrobenzene (cytosol to extracellular)

Catalysed by SLCO1A2, SLCO1B3extracellular space, cytosolOne of 4 routes

1. transport of noradrenaline (cytosol to extracellular)
2. transport of glycoursodeoxycholate (cytosol to extracellular)

Catalysed by SLCO1A2, SLCO1B3extracellular space, cytosolOne of 4 routes