Compound
16alpha-hydroxyestrone
No description recorded for this entry yet. Everything this graph holds about 16alpha-hydroxyestrone is below.
Structure
- Class
- Organic compound
- Formula
- C18H22O3
- Mass
- 286.371 g/mol
- Charge
- 0
- InChIKey
- WPOCIZJTELRQMF-QFXBJFAPSA-N
- SMILES
- [H][C@@]12C[C@@H](O)C(=O)[C@@]1(C)CC[C@]1([H])c3ccc(O)cc3CC[C@@]21[H]
- Look it up
- ChEBIBy InChIKey
Identity from ChEBI. Not evidence — none of it carries a grade.
What it touches on the way
A finding says 16alpha-hydroxyestrone moved an endpoint. This is the biology in between: the proteins and reactions it runs through to get there. It is where to look for the two things a list of findings cannot answer — why a result might happen, and what else acts on the same machinery.
6 of these are proteins with a page of their own, and that is the door: a protein page says what else it carries, which is how one compound leads to the next.
Mechanistic reach
6 entities
6 entities reached, most connected first. Hub metabolites are excluded, so this is not a claim that the compound touches everything.
0 reported hops6 assembled from the scaffold
- CYP3A4ProteinUNIPROT:P08684metabolized byInferred only48 paths48 endpoints
- CYP1A1ProteinUNIPROT:P04798metabolized byInferred only32 paths32 endpoints
- CYP2C8ProteinUNIPROT:P10632metabolized byInferred only29 paths29 endpoints
- UGT2B7ProteinUNIPROT:P16662metabolized byInferred only16 paths16 endpoints
- UGT1A10ProteinUNIPROT:Q9HAW8metabolized byInferred only14 paths14 endpoints
- CYP3A7ProteinUNIPROT:P24462metabolized byInferred only13 paths13 endpoints
What the reference databases state
The section above shows paths a projection assembled. This is the reference layer itself, one step from 16alpha-hydroxyestrone: what the cleared databases state it reacts with, is carried by, is converted to and takes part in, whether or not a projection has walked it yet.
Statements
6 statements
6 statements in 1 reference database name 16alpha-hydroxyestrone — Rhea. Press a relation to see only its rows; every count is the rows behind it.
- 16alpha-hydroxyestrone is metabolised by CYP1A1ProteinRhea RHEA:47204Inferred only
- 16alpha-hydroxyestrone is metabolised by CYP2C8ProteinRhea RHEA:47204Inferred only
- 16alpha-hydroxyestrone is metabolised by CYP3A4ProteinRhea RHEA:47204Inferred only
- 16alpha-hydroxyestrone is metabolised by CYP3A7ProteinRhea RHEA:47204Inferred only
- 16alpha-hydroxyestrone is metabolised by UGT1A10ProteinRhea RHEA:52448Inferred only
- 16alpha-hydroxyestrone is metabolised by UGT2B7ProteinRhea RHEA:52452Inferred only
Other names
11 names
Every name this graph resolves to 16alpha-hydroxyestrone. Searching any of them lands here.
- Also called
- 1.16a-Hydroxyestrone16 alpha OHE16alpha-OHE16alpha-OHE13,16alpha-dihydroxy-1,3,5(10)-estratrien-17-one3,16α-dihydroxy-1,3,5(10)-estratrien-17-oneestra-1,3,5(10)-triene-3,16alpha-diol-17-oneestra-1,3,5(10)-triene-3,16α-diol-17-oneST 18:4;O3
- Systematic name
- 3,16alpha-dihydroxyestra-1,3,5(10)-trien-17-one3,16α-dihydroxyestra-1,3,5(10)-trien-17-one