Compound
taurolithocholate 3-sulfate
A steroid sulfate oxoanion arising from deprotonation of both sulfo groups of taurolithocholic acid sulfate; major species at pH 7.3.
Definition from ChEBI (CHEBI:58301), read 2026-09-23. CC BY 4.0.
Structure
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- Class
- Organic compound, anion
- Formula
- C26H43NO8S2
- Mass
- 561.763 g/mol
- Charge
- -2
- InChIKey
- HSNPMXROZIQAQD-GBURMNQMSA-L
- SMILES
- [H][C@]12CC[C@]3([H])[C@]([H])(CC[C@@]4(C)[C@@]3([H])CC[C@]4([H])[C@H](C)CCC(=O)NCCS(=O)(=O)[O-])[C@@]1(C)CC[C@@H](OS(=O)(=O)[O-])C2
- Look it up
- ChEBIPubChemBy InChIKey
Identity from ChEBI, geometry from PubChem. Not evidence.
What it touches on the way
Mechanistic reach
4 entities
4 entities reached.
0 reported hops4 assembled from the scaffold
What the reference databases state
Statements
14 statements
14 statements · 2 reference databases · Subject: taurolithocholate 3-sulfate · Sources: Human-GEM, Rhea
- taurolithocholate 3-sulfate is converted to taurolithocholateCompoundHuman-GEM MAR01843Inferred only
- taurolithocholate is converted to taurolithocholate 3-sulfateCompoundHuman-GEM MAR01843Inferred only
- taurolithocholate 3-sulfate is metabolised by SULT2A1ProteinRhea RHEA:14013Inferred only
- taurolithocholate 3-sulfate is metabolised by SULT2A1ProteinHuman-GEM MAR01843Inferred only
- taurolithocholate 3-sulfate is transported by ABCC1ProteinHuman-GEM MAR06392Inferred only
- taurolithocholate 3-sulfate is transported by SLC10A6ProteinHuman-GEM MAR09621Inferred only
- taurolithocholate 3-sulfate is transported by SLCO1A2ProteinHuman-GEM MAR06091Inferred only
- taurolithocholate 3-sulfate is transported by SLCO1A2ProteinHuman-GEM MAR06067Inferred only
- taurolithocholate 3-sulfate is transported by SLCO1A2ProteinHuman-GEM MAR06089Inferred only
- taurolithocholate 3-sulfate is transported by SLCO1A2ProteinHuman-GEM MAR06090Inferred only
- taurolithocholate 3-sulfate is transported by SLCO1B3ProteinHuman-GEM MAR06089Inferred only
- taurolithocholate 3-sulfate is transported by SLCO1B3ProteinHuman-GEM MAR06091Inferred only
Show the remaining 2
- taurolithocholate 3-sulfate is transported by SLCO1B3ProteinHuman-GEM MAR06067Inferred only
- taurolithocholate 3-sulfate is transported by SLCO1B3ProteinHuman-GEM MAR06090Inferred only
Reactions
11 reactions
3'-phospho-5'-adenylyl sulfate+taurolithocholateproton+adenosine 3',5'-bismonophosphate+taurolithocholate 3-sulfate
Catalysed by SULT2A1
Reaction pageReversibleBalancedEC 2.8.2.14GO:0005829
Human-GEM MAR01843CC BY 4.0Reference data
Reaction pageReversibleBalance undeterminableGO:0005615
Human-GEM MAR04181CC BY 4.0Reference data
CHEBI:16856+hydrogencarbonate+taurolithocholate 3-sulfateCHEBI:16856+hydrogencarbonate+taurolithocholate 3-sulfate
Transported by SLCO1A2 & SLCO1B3
Reaction pageReversibleBalancedGO:0005829, GO:0005615
Human-GEM MAR06067CC BY 4.0Reference data
MAM01980c+hydrogencarbonate+taurolithocholate 3-sulfateMAM01980e+hydrogencarbonate+taurolithocholate 3-sulfate
Transported by SLCO1A2 & SLCO1B3
Reaction pageReversibleBalance undeterminableGO:0005829, GO:0005615
Human-GEM MAR06089CC BY 4.0Reference data
hydrogencarbonate+2,4-dinitrophenyl-S-glutathione+taurolithocholate 3-sulfatehydrogencarbonate+2,4-dinitrophenyl-S-glutathione+taurolithocholate 3-sulfate
Transported by SLCO1A2 & SLCO1B3
Reaction pageReversibleBalancedGO:0005829, GO:0005615
Human-GEM MAR06090CC BY 4.0Reference data
hydrogencarbonate+MAM02901c+taurolithocholate 3-sulfatehydrogencarbonate+MAM02901e+taurolithocholate 3-sulfate
Transported by SLCO1A2 & SLCO1B3
Reaction pageReversibleBalancedGO:0005829, GO:0005615
Human-GEM MAR06091CC BY 4.0Reference data
ATP+water+taurolithocholate 3-sulfateADP+proton+phosphate(3-)+taurolithocholate 3-sulfate
Transported by ABCC1
Reaction pageLeft to rightBalancedGO:0005829, GO:0005615
Human-GEM MAR06392CC BY 4.0Reference data
sodium(1+)+taurolithocholate 3-sulfatesodium(1+)+taurolithocholate 3-sulfate
Transported by SLC10A6
Reaction pageLeft to rightBalancedGO:0005615, GO:0005829
Human-GEM MAR09621CC BY 4.0Reference data
taurolithocholate+3'-phosphoadenylyl sulfatetaurolithocholate 3-sulfate+adenosine 3',5'-bisphosphate+hydron
Catalysed by SULT2A1
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:14013CC BY 4.0Reference data
taurolithocholate 3-sulfate+ATP(4-)+watertaurolithocholate 3-sulfate+ADP(3-)+hydrogenphosphate+hydron
Transported by ABCC3 or ABCB11 or ABCC2
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:50084CC BY 4.0Reference data
taurolithocholate 3-sulfate+2sodium(1+)taurolithocholate 3-sulfate+2sodium(1+)
Transported by SLC10A6
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:71275CC BY 4.0Reference data
Where it reaches
5 systems, 9 regions, 13 tissues, 13 transporter routes — routes, not measurements: transporters known to carry taurolithocholate 3-sulfate are expressed there, and no source reports it arriving.
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Other names
4 names
Resolves to: taurolithocholate 3-sulfate
- Also called
- taurolithocholate sulfatetaurolithocholic acid sulfate dianion
- Systematic name
- 2-[(24-oxo-3alpha-sulfonatooxy-5beta-cholan-24-yl)amino]ethanesulfonate2-[(24-oxo-3α-sulfonatooxy-5β-cholan-24-yl)amino]ethanesulfonate