5-amino-2-oxopentanoate

1. L-ornithine + pyruvate = 5-amino-2-oxopentanoate + L-alanine
2. transport of acetate and pyruvate (cytosol to extracellular)

Catalysed by AGXT2, SLC16A4, SLC16A5, SLC16A3 and 2 moreextracellular space, cytosolOne of 2 routes

1. L-ornithine + glyoxylate = 5-amino-2-oxopentanoate + glycine
2. glyoxylate + O2 + H2O = oxalate + H2O2 + H(+)

Catalysed by AGXT2, HAO1

1. L-ornithine + pyruvate = 5-amino-2-oxopentanoate + L-alanine
2. transport of formate and pyruvate (cytosol to extracellular)

Catalysed by AGXT2, SLC16A4, SLC16A5, SLC16A7 and 2 moreextracellular space, cytosolOne of 2 routes

1. L-ornithine + pyruvate = 5-amino-2-oxopentanoate + L-alanine
2. transport of propanoate and pyruvate (cytosol to extracellular)

Catalysed by AGXT2, SLC16A4, SLC16A5, SLC16A3 and 3 moreextracellular space, cytosolOne of 2 routes

1. L-ornithine + pyruvate = 5-amino-2-oxopentanoate + L-alanine
2. transport of butyrate and pyruvate (cytosol to extracellular)

Catalysed by AGXT2, SLC16A4, SLC16A5, SLC16A3 and 3 moreextracellular space, cytosolOne of 2 routes

1. L-ornithine + pyruvate = 5-amino-2-oxopentanoate + L-alanine
2. L-Serine:pyruvate aminotransferase

Catalysed by AGXT2, AGXTcytosolOne of 2 routes

1. L-ornithine + pyruvate = 5-amino-2-oxopentanoate + L-alanine
2. L-ornithine(out) + L-lysine(in) = L-ornithine(in) + L-lysine(out)

Catalysed by AGXT2, SLC25A2, SLC25A15inner side of the membrane, outer side of the membraneOne of 2 routes

1. L-ornithine + pyruvate = 5-amino-2-oxopentanoate + L-alanine
2. D-lysine(in) + L-ornithine(out) = D-lysine(out) + L-ornithine(in)

Catalysed by AGXT2, SLC25A2inner side of the membrane, outer side of the membraneOne of 2 routes

1. L-ornithine + pyruvate = 5-amino-2-oxopentanoate + L-alanine
2. L-ornithine carboxy-lyase (putrescine-forming)

Catalysed by AGXT2, ODC1cytosolOne of 3 routes

1. L-ornithine + pyruvate = 5-amino-2-oxopentanoate + L-alanine
2. D-arginine(in) + L-ornithine(out) = D-arginine(out) + L-ornithine(in)

Catalysed by AGXT2, SLC25A2inner side of the membrane, outer side of the membraneOne of 2 routes

1. L-ornithine + pyruvate = 5-amino-2-oxopentanoate + L-alanine
2. 3-oxopropanoate + L-alanine = beta-alanine + pyruvate

Catalysed by AGXT2

1. L-ornithine + pyruvate = 5-amino-2-oxopentanoate + L-alanine
2. D-serine = pyruvate + NH4(+)

Catalysed by AGXT2, SRR

1. L-ornithine + glyoxylate = 5-amino-2-oxopentanoate + glycine
2. L-tyrosine + glyoxylate = 3-(4-hydroxyphenyl)pyruvate + glycine

Catalysed by AGXT2, AADAT

1. L-ornithine + pyruvate = 5-amino-2-oxopentanoate + L-alanine
2. (R)-Lactate:NAD+ oxidoreductase

Catalysed by AGXT2, LDHDcytosol

1. L-ornithine + pyruvate = 5-amino-2-oxopentanoate + L-alanine
2. (S)-Lactate:NAD+ oxidoreductase

Catalysed by AGXT2, LDHB, LDHAL6Bmitochondrial matrixOne of 5 routes

1. L-ornithine + pyruvate = 5-amino-2-oxopentanoate + L-alanine
2. 2-iminopropanoate + H2O = pyruvate + NH4(+)

Catalysed by AGXT2, RIDA

1. L-ornithine + pyruvate = 5-amino-2-oxopentanoate + L-alanine
2. pyruvate kinase (dTDP)

Catalysed by AGXT2, PKM, PKLRcytosol

1. L-ornithine + pyruvate = 5-amino-2-oxopentanoate + L-alanine
2. N-Acetylneuraminate pyruvate-lyase (N-acetyl-D-mannosamine-forming)

Catalysed by AGXT2, NPLcytosol

1. L-ornithine + pyruvate = 5-amino-2-oxopentanoate + L-alanine
2. a 3-acylpyruvate + H2O = a carboxylate + pyruvate + H(+)

Catalysed by AGXT2, FAHD1

1. L-ornithine + pyruvate = 5-amino-2-oxopentanoate + L-alanine
2. L-Arginine:glycine amidinotransferase

Catalysed by AGXT2, GATMcytosolOne of 19 routes

1. L-ornithine + glyoxylate = 5-amino-2-oxopentanoate + glycine
2. L-2-aminoadipate + glyoxylate = 2-oxoadipate + glycine

Catalysed by AGXT2, AADAT

1. L-ornithine + pyruvate = 5-amino-2-oxopentanoate + L-alanine
2. L-histidine(in) + L-ornithine(out) + H(+)(in) = L-histidine(out) + L-ornithine(in) + H(+)(out)

Catalysed by AGXT2, SLC25A2inner side of the membrane, outer side of the membraneOne of 2 routes

1. L-ornithine + pyruvate = 5-amino-2-oxopentanoate + L-alanine
2. D-ornithine(in) + L-ornithine(out) = D-ornithine(out) + L-ornithine(in)

Catalysed by AGXT2, SLC25A2inner side of the membrane, outer side of the membraneOne of 2 routes

1. L-ornithine + pyruvate = 5-amino-2-oxopentanoate + L-alanine
2. 2-oxo-3-sulfanylpropanoate + [thioredoxin]-dithiol = [thioredoxin]-disulfide + hydrogen sulfide + pyruvate + H(+)

Catalysed by AGXT2, MPST

1. L-ornithine + pyruvate = 5-amino-2-oxopentanoate + L-alanine
2. (R)-3-amino-2-methylpropanoate + pyruvate = 2-methyl-3-oxopropanoate + L-alanine

Catalysed by AGXT2

1. L-ornithine + pyruvate = 5-amino-2-oxopentanoate + L-alanine
2. N(1)-methylguanosine(37) in tRNA(Phe) + pyruvate + S-adenosyl-L-methionine = 4-demethylwyosine(37) in tRNA(Phe) + 5'-deoxyadenosine + L-methionine + CO2 + H2O

Catalysed by AGXT2, TYW1B, TYW1One of 3 routes

1. L-ornithine + pyruvate = 5-amino-2-oxopentanoate + L-alanine
2. transport of ornithine and tryptophan (cytosol to extracellular)

Catalysed by AGXT2, SLC7A6extracellular space, cytosolOne of 2 routes

1. L-ornithine + pyruvate = 5-amino-2-oxopentanoate + L-alanine
2. (R)-3-Amino-2-methylpropanoate:pyruvate aminotransferase

Catalysed by AGXT2mitochondrial matrixOne of 21 routes

1. L-ornithine + pyruvate = 5-amino-2-oxopentanoate + L-alanine
2. transport of asparagine and ornithine (cytosol to extracellular)

Catalysed by AGXT2, SLC7A6extracellular space, cytosolOne of 2 routes

1. L-ornithine + pyruvate = 5-amino-2-oxopentanoate + L-alanine
2. L-ornithine + 2-oxoglutarate = L-glutamate 5-semialdehyde + L-glutamate

Catalysed by AGXT2, OAT

1. L-ornithine + pyruvate = 5-amino-2-oxopentanoate + L-alanine
2. transport of ornithine and phenylalanine (cytosol to extracellular)

Catalysed by AGXT2, SLC7A6extracellular space, cytosolOne of 2 routes

1. L-ornithine + pyruvate = 5-amino-2-oxopentanoate + L-alanine
2. N(omega),N(omega)-dimethyl-L-arginine(in) + L-ornithine(out) = N(omega),N(omega)-dimethyl-L-arginine(out) + L-ornithine(in)

Catalysed by AGXT2, SLC25A2inner side of the membrane, outer side of the membraneOne of 2 routes

1. L-ornithine + glyoxylate = 5-amino-2-oxopentanoate + glycine
2. L-kynurenine + glyoxylate = kynurenate + glycine + H2O

Catalysed by AGXT2, KYAT3, AADAT

1. L-ornithine + pyruvate = 5-amino-2-oxopentanoate + L-alanine
2. (3S)-citramalyl-CoA = pyruvate + acetyl-CoA

Catalysed by AGXT2, CLYBL

1. L-ornithine + pyruvate = 5-amino-2-oxopentanoate + L-alanine
2. (4R)-4-hydroxy-2-oxoglutarate = glyoxylate + pyruvate

Catalysed by AGXT2, HOGA1One of 2 routes

1. L-ornithine + glyoxylate = 5-amino-2-oxopentanoate + glycine
2. 3-hydroxy-L-kynurenine + glyoxylate = xanthurenate + glycine + H2O

Catalysed by AGXT2, KYAT3, AADAT

1. L-ornithine + pyruvate = 5-amino-2-oxopentanoate + L-alanine
2. (4S)-4-hydroxy-2-oxoglutarate = glyoxylate + pyruvate

Catalysed by AGXT2, HOGA1One of 2 routes

1. L-ornithine + glyoxylate = 5-amino-2-oxopentanoate + glycine
2. propanoyl-CoA + glyoxylate + H2O = 3-methylmalate + CoA + H(+)

Catalysed by AGXT2, CLYBL

1. L-ornithine + pyruvate = 5-amino-2-oxopentanoate + L-alanine
2. pyruvate:thiamin diphosphate acetaldehydetransferase (decarboxylating)

Catalysed by AGXT2, PDHA1, PDHB, PDHA2mitochondrial matrix

1. L-ornithine + glyoxylate = 5-amino-2-oxopentanoate + glycine
2. L-tyrosine + glyoxylate = 3-(4-hydroxyphenyl)pyruvate + glycine
3. (2R)-2-hydroxy-3-(4-hydroxyphenyl)propanoate + NAD(+) = 3-(4-hydroxyphenyl)pyruvate + NADH + H(+)

Catalysed by AGXT2, AADAT, MDH1

1. L-ornithine + pyruvate = 5-amino-2-oxopentanoate + L-alanine
2. transport of ornithine and tryptophan (cytosol to extracellular)
3. beta-carboline hydrolysis

Catalysed by AGXT2