Compound

(R)-mevalonate

The (R)-enantiomer of mevalonate.

Definition from ChEBI (CHEBI:36464), read 2026-09-23. CC BY 4.0.

CHEBI:36464ChEBI

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Structure

2D depiction · 3D model shown

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A generated conformer of (R)-mevalonate — one low-energy arrangement PubChem computed, not a measured structure. Hydrogens are not drawn; the formula counts them.

Class: Organic compound, anion
Formula: C6H11O4
Mass: 147.15 g/mol
Charge: -1
InChIKey: KJTLQQUUPVSXIM-ZCFIWIBFSA-M
SMILES: C[C@@](O)(CCO)CC(=O)[O-]
Look it up: ChEBI PubChem By InChIKey

Identity from ChEBI, geometry from PubChem. Not evidence.

What it touches on the way

Mechanistic reach

1 entity

1 entities reached.

0 reported hops1 assembled from the scaffold

MVKProteinUNIPROT:Q03426substrate ofInferred only17 paths17 endpoints

What the reference databases state

Statements

4 statements

4 statements · 1 reference database · Subject: (R)-mevalonate · Sources: Rhea

Order

(R)-mevalonate is converted to (3S)-3-hydroxy-3-methylglutaryl-CoACompoundRhea RHEA:14833Inferred only
(3S)-3-hydroxy-3-methylglutaryl-CoA is converted to (R)-mevalonateCompoundRhea RHEA:14833Inferred only
(3S)-3-hydroxy-3-methylglutaryl-CoA is converted to (R)-mevalonateCompoundRhea RHEA:15989Inferred only
(R)-mevalonate is a substrate of MVKProteinRhea RHEA:17065Inferred only

Reactions

6 reactions

(R)-mevalonate+NAD(1-)CHEBI:195523+NADH(2-)+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:13221CC BY 4.0Reference data
(R)-mevalonate+2NAD(1-)+coenzyme A(4-)(3S)-3-hydroxy-3-methylglutaryl-CoA+2NADH(2-)+2hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:14833CC BY 4.0Reference data
(R)-mevalonate+2NADP(3-)+coenzyme A(4-)(3S)-3-hydroxy-3-methylglutaryl-CoA+2NADPH(4-)+2hydron
Catalysed by HMGCR
Reaction pageRight to leftBalanced
Rhea RHEA:15989CC BY 4.0Reference data
(R)-mevalonate+ATP(4-)CHEBI:58146+ADP(3-)+hydron
Catalysed by MVK
Reaction pageDirection not assertedBalanced
Rhea RHEA:17065CC BY 4.0Reference data
(R)-mevalonate+NADP(3-)CHEBI:195523+NADPH(4-)+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:20193CC BY 4.0Reference data
(R)-mevalonate+ATP(4-)CHEBI:82773+ADP(3-)+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:42884CC BY 4.0Reference data

Other names

8 names

Resolves to: (R)-mevalonate

Also called: (3R)-3,5-dihydroxy-3-methylvalerate(3R)-mevalonate(R)-3,5-dihydroxy-3-methylpentanoate(R)-mevalonic acid anion(R)-mevalonic acid(1-)(R)-mevalonic acid(1−)D-mevalonate
Systematic name: (3R)-3,5-dihydroxy-3-methylpentanoate