Compound
a (3S)-3-hydroxyacyl-CoA
The tetraanion of an (S)-3-hydroxyacyl-CoA compound.
Definition from ChEBI (CHEBI:57318), read 2026-09-23. CC BY 4.0.
Structure
- Class
- Organic compound, anion
- Formula
- C24H35N7O18P3SR
- Mass
- 834.557 g/mol
- Charge
- -4
- SMILES
- [1*][C@H](O)CC(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP(=O)([O-])OP(=O)([O-])OC[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1OP(=O)([O-])[O-]
- Look it up
- ChEBI
Identity from ChEBI. Not evidence.
What it touches on the way
Mechanistic reach
5 entities
5 entities reached.
0 reported hops5 assembled from the scaffold
- EHHADHProteinUNIPROT:Q08426substrate ofInferred only42 paths21 endpoints
- ECHS1ProteinUNIPROT:P30084substrate ofInferred only38 paths38 endpoints
- HADHAProteinUNIPROT:P40939substrate ofInferred only37 paths37 endpoints
- HSD17B10ProteinUNIPROT:Q99714substrate ofInferred only33 paths33 endpoints
- HADHProteinUNIPROT:Q16836substrate ofInferred only22 paths22 endpoints
What the reference databases state
Statements
12 statements
12 statements · 1 reference database · Subject: a (3S)-3-hydroxyacyl-CoA · Sources: Rhea
- a (3S)-3-hydroxyacyl-CoA is converted to a (2E)-enoyl-CoACompoundRhea RHEA:16105Inferred only
- a (2E)-enoyl-CoA is converted to a (3S)-3-hydroxyacyl-CoACompoundRhea RHEA:16105Inferred only
- a (3S)-3-hydroxyacyl-CoA is converted to a (3R)-3-hydroxyacyl-CoACompoundRhea RHEA:34083Inferred only
- a (3R)-3-hydroxyacyl-CoA is converted to a (3S)-3-hydroxyacyl-CoACompoundRhea RHEA:34083Inferred only
- a (3S)-3-hydroxyacyl-CoA is converted to a 3-oxoacyl-CoACompoundRhea RHEA:22432Inferred only
- a 3-oxoacyl-CoA is converted to a (3S)-3-hydroxyacyl-CoACompoundRhea RHEA:22432Inferred only
- a (3S)-3-hydroxyacyl-CoA is a substrate of ECHS1ProteinRhea RHEA:16105Inferred only
- a (3S)-3-hydroxyacyl-CoA is a substrate of EHHADHProteinRhea RHEA:16105Inferred only
- a (3S)-3-hydroxyacyl-CoA is a substrate of EHHADHProteinRhea RHEA:22432Inferred only
- a (3S)-3-hydroxyacyl-CoA is a substrate of HADHProteinRhea RHEA:22432Inferred only
- a (3S)-3-hydroxyacyl-CoA is a substrate of HADHAProteinRhea RHEA:16105Inferred only
- a (3S)-3-hydroxyacyl-CoA is a substrate of HSD17B10ProteinRhea RHEA:22432Inferred only
Reactions
3 reactions
a (3S)-3-hydroxyacyl-CoAa (2E)-enoyl-CoA+water
Catalysed by ECHS1 or HADHA or EHHADH
Reaction pageReversibleBalance undeterminable
Rhea RHEA:16105CC BY 4.0Reference data
a (3S)-3-hydroxyacyl-CoA+NAD(1-)a 3-oxoacyl-CoA+NADH(2-)+hydron
Catalysed by EHHADH or HADH or HSD17B10
Reaction pageReversibleBalance undeterminable
Rhea RHEA:22432CC BY 4.0Reference data
a (3R)-3-hydroxyacyl-CoAa (3S)-3-hydroxyacyl-CoA
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:34083CC BY 4.0Reference data
Other names
1 name
Resolves to: a (3S)-3-hydroxyacyl-CoA
- Also called
- (3S)-hydroxy fatty acyl-CoAs