a 3-oxoacyl-CoA

1. a (3S)-3-hydroxyacyl-CoA + NAD(+) = a 3-oxoacyl-CoA + NADH + H(+)

Catalysed by EHHADH, HADH, HSD17B10

1. an acyl-CoA + acetyl-CoA = a 3-oxoacyl-CoA + CoA

Catalysed by ACAA1, SCP2, ACAA2, HADHB

1. an acyl-CoA + acetyl-CoA = a 3-oxoacyl-CoA + CoA
2. acyl-CoA:sn-glycerol-3-phosphate 1-O-acyltransferase

Catalysed by ACAA1, SCP2, ACAA2, HADHB and 4 moremitochondrial matrixOne of 16 routes

1. an acyl-CoA + acetyl-CoA = a 3-oxoacyl-CoA + CoA
2. an acyl-CoA + H2O = an acyl-4'-phosphopantetheine + adenosine 3',5'-bisphosphate + 2 H(+)

Catalysed by ACAA1, SCP2, ACAA2, HADHB and 3 more