Compound
porphobilinogen
Conjugate base of porphobilinogen arising from deprotonation of the two carboxy groups and protonation of the amino group; major species at pH 7.3.
Definition from ChEBI (CHEBI:58126), read 2026-09-23. CC BY 4.0.
Structure
No depiction stored
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- Class
- Organic compound, anion
- Formula
- C10H13N2O4
- Mass
- 225.224 g/mol
- Charge
- -1
- InChIKey
- QSHWIQZFGQKFMA-UHFFFAOYSA-M
- SMILES
- [NH3+]Cc1ncc(CCC(=O)[O-])c1CC(=O)[O-]
- Look it up
- ChEBIPubChemBy InChIKey
Identity from ChEBI, geometry from PubChem. Not evidence.
What it touches on the way
Mechanistic reach
2 entities
2 entities reached.
0 reported hops2 assembled from the scaffold
What the reference databases state
Statements
6 statements
6 statements · 2 reference databases · Subject: porphobilinogen · Sources: Human-GEM, Rhea
- porphobilinogen is converted to 5-aminolevulinateCompoundRhea RHEA:24064Inferred only
- 5-aminolevulinate is converted to porphobilinogenCompoundRhea RHEA:24064Inferred only
- 5-aminolevulinic acid is converted to porphobilinogenCompoundHuman-GEM MAR04744Inferred only
- porphobilinogen is a substrate of ALADProteinRhea RHEA:24064Inferred only
- porphobilinogen is a substrate of HMBSProteinHuman-GEM MAR04746Inferred only
- porphobilinogen is a substrate of HMBSProteinRhea RHEA:13185Inferred only
Reactions
6 reactions
25-aminolevulinic acidproton+2water+porphobilinogen
Catalysed by ALAD
Reaction pageLeft to rightBalancedEC 4.2.1.24cytosol
Human-GEM MAR04744CC BY 4.0Reference data
water+4porphobilinogen4proton+MAM02151c+4ammonium
Catalysed by HMBS
Reaction pageLeft to rightBalancedEC 2.5.1.61cytosol
Human-GEM MAR04746CC BY 4.0Reference data
porphobilinogenporphobilinogen
Reaction pageReversibleBalancedcytosol, extracellular space
Human-GEM MAR11931CC BY 4.0Reference data
Reaction pageReversibleBalance undeterminableextracellular space
Human-GEM MAR11932CC BY 4.0Reference data
4porphobilinogen+waterCHEBI:57845+4ammonium
Catalysed by HMBS
Reaction pageLeft to rightBalanced
Rhea RHEA:13185CC BY 4.0Reference data
25-aminolevulinateporphobilinogen+2water+hydron
Catalysed by ALAD
Reaction pageDirection not assertedBalanced
Rhea RHEA:24064CC BY 4.0Reference data
Other names
2 names
Resolves to: porphobilinogen
- Also called
- porphobilinogen anion
- Systematic name
- 3-[5-(azaniumylmethyl)-4-(carboxylatomethyl)-1H-pyrrol-3-yl]propanoate