Compound
(2E)-glutaconyl-CoA
Pentaanion of trans-4-carboxybut-2-enoyl-CoA arising from deprotonation of phosphate, diphosphate and carboxylic acid functions.
Definition from ChEBI (CHEBI:57353), read 2026-09-23. CC BY 4.0.
Structure
No three-dimensional record for this entry.
- Class
- Organic compound, anion
- Formula
- C26H35N7O19P3S
- Mass
- 874.585 g/mol
- Charge
- -5
- InChIKey
- URTLOTISFJPPOU-DEGQQWIJSA-I
- SMILES
- CC(C)(COP(=O)([O-])OP(=O)([O-])OC[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1OP(=O)([O-])[O-])[C@@H](O)C(=O)NCCC(=O)NCCSC(=O)/C=C/CC(=O)[O-]
- Look it up
- ChEBIBy InChIKey
Identity from ChEBI. Not evidence.
What it touches on the way
Mechanistic reach
1 entity
1 entities reached.
0 reported hops1 assembled from the scaffold
What the reference databases state
Statements
6 statements
6 statements · 1 reference database · Subject: (2E)-glutaconyl-CoA · Sources: Rhea
- (2E)-glutaconyl-CoA is converted to (2E)-butenoyl-CoACompoundRhea RHEA:23972Inferred only
- (2E)-glutaconyl-CoA is converted to (2E)-butenoyl-CoACompoundRhea RHEA:60572Inferred only
- (2E)-butenoyl-CoA is converted to (2E)-glutaconyl-CoACompoundRhea RHEA:23972Inferred only
- (2E)-butenoyl-CoA is converted to (2E)-glutaconyl-CoACompoundRhea RHEA:60572Inferred only
- glutaryl-CoA is converted to (2E)-glutaconyl-CoACompoundRhea RHEA:40315Inferred only
- (2E)-glutaconyl-CoA is a substrate of AUHProteinRhea RHEA:68456Inferred only
Reactions
8 reactions
glutaryl-CoA+oxidized [electron-transfer flavoprotein]+hydron(2E)-glutaconyl-CoA+reduced [electron-transfer flavoprotein]
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:20589CC BY 4.0Reference data
CHEBI:36460+acetyl-CoA(2E)-glutaconyl-CoA+acetate
Reaction pageDirection not assertedBalanced
Rhea RHEA:23208CC BY 4.0Reference data
(2E)-glutaconyl-CoA+sodium(1+)+hydron(2E)-butenoyl-CoA+sodium(1+)+carbon dioxide
Reaction pageDirection not assertedBalanced
Rhea RHEA:23972CC BY 4.0Reference data
glutaryl-CoA+dioxygen(2E)-glutaconyl-CoA+hydrogen peroxide
Catalysed by ACOX1
Reaction pageLeft to rightBalanced
Rhea RHEA:40315CC BY 4.0Reference data
CHEBI:132946(2E)-glutaconyl-CoA+water
Reaction pageDirection not assertedBalanced
Rhea RHEA:42448CC BY 4.0Reference data
glutaryl-CoA+A(2E)-glutaconyl-CoA+AH2
Reaction pageDirection not assertedBalanced
Rhea RHEA:47420CC BY 4.0Reference data
(2E)-glutaconyl-CoA+hydron(2E)-butenoyl-CoA+carbon dioxide
Reaction pageDirection not assertedBalanced
Rhea RHEA:60572CC BY 4.0Reference data
CHEBI:177916(2E)-glutaconyl-CoA+water
Catalysed by AUH
Reaction pageRight to leftBalanced
Rhea RHEA:68456CC BY 4.0Reference data
Other names
2 names
Resolves to: (2E)-glutaconyl-CoA
- Also called
- (3E)-pentadienoyl-CoA
- Systematic name
- 3'-phosphonatoadenosine 5'-{3-[(3R)-4-({3-[(2-{[(2E)-4-carboxylatobut-2-enoyl]sulfanyl}ethyl)amino]-3-oxopropyl}amino)-3-hydroxy-2,2-dimethyl-4-oxobutyl] diphosphate}