17alpha-hydroxypregnenolone

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

162 compounds within 3 steps: 5 in 1, 31 in 2, 126 in 3

One step

acetaldehydeReach from here →
1. cytochrome P450 (17alpha-hydroxypregnenolone)
Catalysed by CYP17A1cytosolOne of 2 routes
17alpha-hydroxyprogesteroneReach from here →
1. 17alpha-Hydroxypregnenolone:NAD+ 3-oxidoreductase
Catalysed by HSD3B1, HSD3B2endoplasmic reticulumOne of 2 routes
17alpha,21-dihydroxypregnenoloneReach from here →
1. cytochrome P450
Catalysed by CYP21A2cytosol
3beta-hydroxyandrost-5-en-17-oneReach from here →
1. cytochrome P450 (17alpha-hydroxypregnenolone)
Catalysed by CYP17A1cytosolOne of 6 routes
acetateReach from here →
1. cytochrome P450 (17alpha-hydroxypregnenolone)
Catalysed by CYP17A1cytosolOne of 4 routes

Two steps

2-hydroxybutyric acidReach from here →
1. cytochrome P450 (17alpha-hydroxypregnenolone)
2. transport of 2-hydroxybutyrate and acetate (cytosol to extracellular)
Catalysed by CYP17A1, SLC16A4, SLC16A5, SLC16A7 and 1 morecytosol, extracellular spaceOne of 2 routes
N-acetylcadaverineReach from here →
1. cytochrome P450 (17alpha-hydroxypregnenolone)
2. N-acetylcadaverine + H2O = cadaverine + acetate
Catalysed by CYP17A1, HDAC10cytosol

Three steps

acetoacetate

Reach from here →

Catalysed by CYP17A1, SLC16A4, SLC16A5, SLC16A6 and 2 morecytosol, extracellular spaceOne of 2 routes

a phenyl acetateReach from here →

Catalysed by CYP17A1, PON1, PON2, PON3cytosol

acetylpyruvateReach from here →

Catalysed by CYP17A1, FAHD1cytosol

pyruvateReach from here →

Catalysed by CYP17A1, SLC16A4, SLC16A5, SLC16A3 and 2 morecytosol, extracellular spaceOne of 2 routes

all-trans-retinoic acidReach from here →

Catalysed by CYP17A1, SLC16A4, SLC16A5, SLC16A7cytosol, extracellular spaceOne of 2 routes

CHEBI:16132Reach from here →

Catalysed by CYP17A1, DERAcytosol

(17R,20S)-17,20-dihydroxypregn-4-en-3-oneReach from here →

Catalysed by HSD3B1, HSD3B2, AKR1C1endoplasmic reticulumOne of 2 routes

androst-4-ene-3,17-dioneReach from here →

Catalysed by CYP17A1, HSD3B1, HSD3B2cytosol, endoplasmic reticulumOne of 6 routes

N(2)-acetyl-L-ornithineReach from here →

Catalysed by CYP17A1, ACY1cytosol

(R)-3-hydroxybutyric acidReach from here →

Catalysed by CYP17A1, SLC16A4, SLC16A5, SLC16A7 and 1 morecytosol, extracellular spaceOne of 2 routes

4-methylumbelliferyl acetateReach from here →

Catalysed by CYP17A1, CES2, ESD, CES1cytosol

androst-5-en-3beta,17beta-diolReach from here →

Catalysed by CYP17A1, AKR1B15, HSD17B3cytosol

3beta,16alpha-dihydroxy-androst-5-en-17-oneReach from here →

Catalysed by CYP17A1, CYP3A7cytosol

11-deoxycortisolReach from here →

Catalysed by CYP21A2, HSD3B1, HSD3B2cytosolOne of 4 routes

formic acidReach from here →

Catalysed by CYP17A1, SLC16A4, SLC16A5, SLC16A1cytosol, extracellular spaceOne of 2 routes

propionic acidReach from here →

Catalysed by CYP17A1, SLC16A4, SLC16A5, SLC16A7 and 1 morecytosol, extracellular spaceOne of 2 routes

butyric acidReach from here →

Catalysed by CYP17A1, SLC16A4, SLC16A5, SLC16A7 and 1 morecytosol, extracellular spaceOne of 2 routes

(S)-lactic acidReach from here →

Catalysed by CYP17A1, SLC16A4, SLC16A5, SLC16A3 and 3 morecytosol, extracellular spaceOne of 2 routes

N-(acetyl)-sphing-4-enineReach from here →

Catalysed by CYP17A1, ASAH1cytosol

N-acetyl-D-glucosamine 6-phosphateReach from here →

Catalysed by CYP17A1, AMDHD2cytosol

dehydroepiandrosterone 3-sulfateReach from here →

Catalysed by CYP17A1, SULT1E1cytosolOne of 3 routes

phosphoethanolamineReach from here →

Catalysed by CYP17A1, ETNPPLcytosol

N-acetylputrescineReach from here →

Catalysed by CYP17A1, HDAC10cytosol

N(8)-acetylspermidineReach from here →

Catalysed by CYP17A1, HDAC10cytosol

an N-acetyl-L-cysteine-S-conjugateReach from here →

Catalysed by CYP17A1, ACY3cytosol

2-deoxy-D-ribose 5-phosphateReach from here →

Catalysed by CYP17A1, DERAcytosol

16alpha,17alpha-dihydroxyprogesteroneReach from here →

Catalysed by HSD3B1, HSD3B2, CYP17A1endoplasmic reticulum

3beta,7alpha-dihydroxyandrost-5-en-17-oneReach from here →

Catalysed by CYP17A1, CYP7B1cytosol

androst-5-ene-3,17-dioneReach from here →

Catalysed by CYP17A1, HSD3B1, HSD3B2cytosolOne of 3 routes

Catalysed by CYP17A1, SLC16A4, SLC16A5, SLC16A3 and 3 morecytosol, extracellular spaceOne of 2 routes

prostaglandin A2Reach from here →

Catalysed by CYP17A1, SLC16A4, SLC16A5, SLC16A3 and 3 morecytosol, extracellular spaceOne of 2 routes

prostaglandin J2Reach from here →

Catalysed by CYP17A1, SLC16A4, SLC16A5, SLC16A3 and 3 morecytosol, extracellular spaceOne of 2 routes

15-oxoprostaglandin F2alphaReach from here →

Catalysed by CYP17A1, SLC16A4, SLC16A5, SLC16A3 and 3 morecytosol, extracellular spaceOne of 2 routes

2,4-dinitrophenyl-S-glutathioneReach from here →

Catalysed by CYP17A1, SULT1E1, SLCO1B1cytosol, extracellular spaceOne of 2 routes

all-trans-4-hydroxyretinoateReach from here →

Catalysed by CYP17A1, SLC16A4, SLC16A5, SLC16A7 and 1 morecytosol, extracellular spaceOne of 3 routes

6beta,16alpha,17alpha-trihydroxyprogesteroneReach from here →

Catalysed by HSD3B1, HSD3B2, CYP17A1endoplasmic reticulum

all-trans-retinoyl-1-O-(beta-D-glucuronate)Reach from here →

Catalysed by CYP17A1, SLC16A4, SLC16A5, SLC16A7 and 3 morecytosol, extracellular space, endoplasmic reticulum

all-trans-18-hydroxyretinoateReach from here →

Catalysed by CYP17A1, SLC16A4, SLC16A5, SLC16A7 and 25 morecytosol, extracellular spaceOne of 2 routes

17beta-hydroxy-androst-5-en-3-oneReach from here →

Catalysed by CYP17A1, AKR1B15, HSD17B3, HSD3B1cytosol

2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol)Reach from here →

Catalysed by CYP17A1, ASAH1, PLA2G15cytosol

2-nonadioyl-sn-glycero-3-phosphocholineReach from here →

Catalysed by CYP17A1, ASAH1, PLA2G15cytosol

CHEBI:15345Reach from here →

Catalysed by CYP17A1, SLC16A4, SLC16A5, SLC16A6 and 3 morecytosol, extracellular spaceOne of 3 routes