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Proteins/UNIPROT:O15403
Monocarboxylate transporter selective for taurine. May associate with BSG/CD147 or EMB/GP70 ancillary proteins to mediate facilitative efflux or influx of taurine across the plasma membrane. The transport is pH- and sodium-independent. Rather low-affinity, is likely effective for taurine transport in tissues where taurine is present at high concentrations..
Function from UniProtKB (O15403), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
64 statements
64 statements · 3 reference databases · Subject: SLC16A6 · Sources: Hetionet, Human-GEM, Rhea
10 reactions
(R)-lactic acid+proton(R)-lactic acid+proton
Transported by SLC16A8 or SLC16A6 or SLC16A7 or SLC16A3 or SLC16A1 or SLC16A4 or SLC16A5
Reaction pageLeft to rightBalancedextracellular space, cytosol
Human-GEM MAR03858CC BY 4.0Reference data
6 names
Resolves to: SLC16A6
Reaction pageLeft to rightBalancedextracellular space, cytosol
Human-GEM MAR04928CC BY 4.0Reference data
acetoacetate+protonacetoacetate+proton
Transported by SLC16A8 or SLC16A6 or SLC16A7 or SLC16A1 or SLC16A4 or SLC16A5
Reaction pageLeft to rightBalancedextracellular space, cytosol
Human-GEM MAR04976CC BY 4.0Reference data
2-oxobutanoate+proton2-oxobutanoate+proton
Transported by SLC16A8 or SLC16A6 or SLC16A7 or SLC16A3 or SLC16A1 or SLC16A4 or SLC16A5
Reaction pageLeft to rightBalancedcytosol, mitochondrial matrix
Human-GEM MAR05348CC BY 4.0Reference data
2-oxobutanoate+proton2-oxobutanoate+proton
Transported by SLC16A8 or SLC16A6 or SLC16A7 or SLC16A3 or SLC16A1 or SLC16A4 or SLC16A5
Reaction pageLeft to rightBalancedmitochondrial matrix, mitochondrial intermembrane space, cytosol
Human-GEM MAR05349CC BY 4.0Reference data
acetate+acetoacetateacetate+acetoacetate
Transported by SLC16A6 or SLC16A7 or SLC16A1 or SLC16A4 or SLC16A5
Reaction pageReversibleBalancedcytosol, extracellular space
Human-GEM MAR06001CC BY 4.0Reference data
2-hydroxybutyric acid+(S)-lactic acid2-hydroxybutyric acid+(S)-lactic acid
Transported by SLC16A8 or SLC16A6 or SLC16A7 or SLC16A3 or SLC16A1 or SLC16A4 or SLC16A5
Reaction pageReversibleBalancedcytosol, extracellular space
Human-GEM MAR06011CC BY 4.0Reference data
(R)-3-hydroxybutyric acid+2-oxoglutarate(2-)(R)-3-hydroxybutyric acid+2-oxoglutarate(2-)
Transported by SLC16A6 or SLC16A7 or SLC16A1 or SLC16A4 or SLC16A5
Reaction pageReversibleBalancedcytosol, extracellular space
Human-GEM MAR06029CC BY 4.0Reference data
(R)-3-hydroxybutyric acid+2-hydroxybutyric acid(R)-3-hydroxybutyric acid+2-hydroxybutyric acid
Transported by SLC16A6 or SLC16A7 or SLC16A3 or SLC16A1 or SLC16A4 or SLC16A5
Reaction pageReversibleBalancedcytosol, extracellular space
Human-GEM MAR06054CC BY 4.0Reference data
Transported by SLC16A6 or LRRC8E or LRRC8B or LRRC8D or LRRC8A or LRRC8C
Reaction pageReversibleBalanced
Rhea RHEA:66328CC BY 4.0Reference data