Structure
Loading the model…
- Class
- Organic compound
- Formula
- C19H28O3
- Mass
- 304.43 g/mol
- Charge
- 0
- InChIKey
- QQIVKFZWLZJXJT-DNKQKWOHSA-N
- SMILES
- [H][C@@]12CC=C3C[C@@H](O)CC[C@]3(C)[C@@]1([H])CC[C@]1(C)C(=O)[C@H](O)C[C@@]21[H]
- Look it up
- ChEBIPubChemBy InChIKey
Identity from ChEBI, geometry from PubChem. Not evidence.
What it touches on the way
Mechanistic reach
3 entities
3 entities reached.
What the reference databases state
Statements
8 statements
8 statements · 1 reference database · Subject: 3beta,16alpha-dihydroxy-androst-5-en-17-one · Sources: Human-GEM
- 3beta,16alpha-dihydroxy-androst-5-en-17-one is converted to 5alpha-androstan-3,17-dioneCompoundHuman-GEM MAR07972Inferred only
- 3beta,16alpha-dihydroxy-androst-5-en-17-one is converted to 5alpha-androstan-3,17-dioneCompoundHuman-GEM MAR07971Inferred only
- androsterone is converted to 3beta,16alpha-dihydroxy-androst-5-en-17-oneCompoundHuman-GEM MAR07970Inferred only
- 3beta,16alpha-dihydroxy-androst-5-en-17-one is a substrate of HSD3B1ProteinHuman-GEM MAR07972Inferred only
- 3beta,16alpha-dihydroxy-androst-5-en-17-one is a substrate of HSD3B1ProteinHuman-GEM MAR07971Inferred only
- 3beta,16alpha-dihydroxy-androst-5-en-17-one is a substrate of HSD3B2ProteinHuman-GEM MAR07972Inferred only
- 3beta,16alpha-dihydroxy-androst-5-en-17-one is a substrate of HSD3B2ProteinHuman-GEM MAR07971Inferred only
- 3beta,16alpha-dihydroxy-androst-5-en-17-one is transported by ABCB1ProteinHuman-GEM MAR11758Inferred only
Reactions
8 reactions
androsterone+proton+NADPH(4-)+1.5dioxygen3beta,16alpha-dihydroxy-androst-5-en-17-one+2water+NADP(3-)
Catalysed by HSD17B7
Reaction pageLeft to rightBalancedEC 1.1.1.270endoplasmic reticulum
Human-GEM MAR07970CC BY 4.0Reference data
3beta,16alpha-dihydroxy-androst-5-en-17-one+proton+NADH(2-)5alpha-androstan-3,17-dione+water+NAD(+)
Reaction pageLeft to rightBalancedEC 5.3.3.1endoplasmic reticulum
Human-GEM MAR07971CC BY 4.0Reference data
3beta,16alpha-dihydroxy-androst-5-en-17-one+proton+NADPH(4-)5alpha-androstan-3,17-dione+water+NADP(3-)
Reaction pageLeft to rightBalancedEC 5.3.3.1endoplasmic reticulum
Human-GEM MAR07972CC BY 4.0Reference data
3beta,16alpha-dihydroxy-androst-5-en-17-one+ATP+water3beta,16alpha-dihydroxy-androst-5-en-17-one+ADP+proton+phosphate(3-)
Transported by ABCB1
Reaction pageLeft to rightBalancedcytosol, extracellular space
Human-GEM MAR11758CC BY 4.0Reference data
3beta,16alpha-dihydroxy-androst-5-en-17-one+ATP+water3beta,16alpha-dihydroxy-androst-5-en-17-one+ADP+proton+phosphate(3-)
Reaction pageLeft to rightBalancedendoplasmic reticulum, cytosol
Human-GEM MAR11851CC BY 4.0Reference data
3beta,16alpha-dihydroxy-androst-5-en-17-one
Reaction pageReversibleBalance undeterminableextracellular space
Human-GEM MAR11852CC BY 4.0Reference data
3beta-hydroxyandrost-5-en-17-one+reduced [NADPH--hemoprotein reductase]+dioxygen3beta,16alpha-dihydroxy-androst-5-en-17-one+oxidized [NADPH--hemoprotein reductase]+water+hydron
Catalysed by CYP17A1 or CYP3A7
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:47220CC BY 4.0Reference data
16alpha,17alpha-dihydroxypregnenolone+reduced [NADPH--hemoprotein reductase]+dioxygen3beta,16alpha-dihydroxy-androst-5-en-17-one+acetate+oxidized [NADPH--hemoprotein reductase]+water+2hydron
Catalysed by CYP17A1
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:53224CC BY 4.0Reference data
Where it reaches
3 systems, 6 regions, 11 tissues, 11 transporter routes — routes, not measurements: transporters known to carry 3beta,16alpha-dihydroxy-androst-5-en-17-one are expressed there, and no source reports it arriving.
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Other names
7 names
Resolves to: 3beta,16alpha-dihydroxy-androst-5-en-17-one
- Also called
- 16alpha-Hydroxydehydroepiandrosterone16alpha-Hydroxydehydroisoandrosterone3beta,16alpha-dihydroxy-5-androsten-17-one5-Androstene-3beta,16alpha-diol-17-oneST 19:2;O3
- Systematic name
- 3beta,16alpha-dihydroxyandrost-5-en-17-one3β,16α-dihydroxyandrost-5-en-17-one