3beta,16alpha-dihydroxy-androst-5-en-17-one
362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API
20 compounds within 3 steps: 1 in 1, 4 in 2, 15 in 3
One step
Two steps
Catalysed by HSD3B1, HSD3B2, AKR1C4, AKR1C3 and 2 moreendoplasmic reticulum, cytosolOne of 6 routes
- steroid Delta-isomerase (16alpha-hydroxydehydroepiandrosterone)
- 17beta-hydroxy-5alpha-androstan-3-one + NADP(+) = 5alpha-androstan-3,17-dione + NADPH + H(+)
Catalysed by HSD3B1, HSD3B2, AKR1B15, HSD17B3 and 1 moreendoplasmic reticulum
Three steps
- steroid Delta-isomerase (16alpha-hydroxydehydroepiandrosterone)
- Androsterone:NAD+ oxidoreductase
- steroid sulfatase (androsterone sulfate)
Catalysed by HSD3B1, HSD3B2, AKR1C4, AKR1C3 and 3 moreendoplasmic reticulum, cytosolOne of 4 routes