Compound

6beta,16alpha,17alpha-trihydroxyprogesterone

A 3-oxo-Δ4 steroid that is progesterone substituted by hydroxy groups at positions 6, 16 and 17 (6β,16α,17α-stereoisomer).

Definition from ChEBI (CHEBI:137046), read 2026-09-23. CC BY 4.0.

CHEBI:137046ChEBI

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Structure

2D depiction · 3D model shown

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A generated conformer of 6beta,16alpha,17alpha-trihydroxyprogesterone — one low-energy arrangement PubChem computed, not a measured structure. Hydrogens are not drawn; the formula counts them.

Class: Organic compound
Formula: C21H30O5
Mass: 362.466 g/mol
Charge: 0
InChIKey: SSBCUQUXYYMNRG-NAUTVQSMSA-N
SMILES: [H][C@@]12C[C@@H](O)C3=CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@@]1(C)[C@@]2([H])C[C@@H](O)[C@]1(O)C(C)=O
Look it up: ChEBI PubChem By InChIKey

Identity from ChEBI, geometry from PubChem. Not evidence.

What it touches on the way

Mechanistic reach

1 entity

1 entities reached.

0 reported hops1 assembled from the scaffold

CYP17A1ProteinUNIPROT:P05093metabolized byInferred only28 paths28 endpoints

What the reference databases state

Chemical structure

6beta,16alpha,17alpha-trihydroxyprogesterone has the functional parent progesteroneCompoundChEBI CHEBI:137046Inferred only

Statements

1 statement

1 statement · 1 reference database · Subject: 6beta,16alpha,17alpha-trihydroxyprogesterone · Sources: Rhea

Order

6beta,16alpha,17alpha-trihydroxyprogesterone is metabolised by CYP17A1ProteinRhea RHEA:53220Inferred only

Reactions

1 reaction

16alpha,17alpha-dihydroxyprogesterone+reduced [NADPH--hemoprotein reductase]+dioxygen6beta,16alpha,17alpha-trihydroxyprogesterone+oxidized [NADPH--hemoprotein reductase]+water+hydron
Catalysed by CYP17A1
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:53220CC BY 4.0Reference data

Other names

6 names

Resolves to: 6beta,16alpha,17alpha-trihydroxyprogesterone

Also called: (6beta,16alpha)-6,16,17-trihydroxypregn-4-ene-3,20-dione(6β,16α)-6,16,17-trihydroxypregn-4-ene-3,20-dione6beta,16alpha,17alpha-trihydroxy-4-pregnene-3,20-dione6β,16α,17α-trihydroxy-4-pregnene-3,20-dione
Systematic name: 6beta,16alpha,17-trihydroxypregn-4-ene-3,20-dione6β,16α,17-trihydroxypregn-4-ene-3,20-dione