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Proteins/UNIPROT:Q9Y303
Hydrolyzes the N-glycolyl group from N-glycolylglucosamine 6-phosphate (GlcNGc-6-P) in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway. Although human is not able to catalyze formation of Neu5Gc due to the inactive CMAHP enzyme, Neu5Gc is present in food and must be degraded..
Function from UniProtKB (Q9Y303), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
302 statements
302 statements · 7 reference databases · Subject: AMDHD2 · Sources: gene ontology, Hetionet, Human Protein Atlas, Human-GEM, Reactome, Rhea, UniProt · Rows fetched: 300
2 reactions
water+N-acetyl-D-glucosamine 6-phosphateacetate+alpha-D-glucosamine 6-phosphate
Reaction pageLeft to rightBalancedEC 3.5.1.25cytosol
Human-GEM MAR04629CC BY 4.0Reference data
N-acetyl-D-glucosamine 6-phosphate+waterD-glucosamine 6-phosphate+acetate
Catalysed by AMDHD2
2 names
Resolves to: AMDHD2
Rhea RHEA:22936CC BY 4.0Reference data