UDP-alpha-D-glucose

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

146 compounds within 3 steps: 6 in 1, 49 in 2, 91 in 3

Three steps

D-glucopyranose 6-phosphateReach from here →
1. an N-acylsphing-4-enine + UDP-alpha-D-glucose = a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + UDP + H(+)
2. a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + H2O = an N-acylsphing-4-enine + D-glucose
3. ATP:D-glucose 6-phosphotransferase
Catalysed by UGCG, GBA1, GBA3, GBA2 and 5 morecytosolOne of 5 routes
N-acetyl-beta-neuraminic acidReach from here →
1. alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose = alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose
2. a ganglioside GM2 (d18:1(4E)) + UDP-alpha-D-galactose = a ganglioside GM1 (d18:1(4E)) + UDP + H(+)
3. Sialidase, Cytosol (Neu2)
Catalysed by GALT, B3GALT4, NEU2cytosolOne of 3 routes
a 6-(N-acetyl-alpha-D-glucosaminyl)-1-(1,2-diacyl-sn-glycero-3-phospho)-1D-myo-inositolReach from here →
1. alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose = alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose
2. UDP-N-acetyl-alpha-D-glucosamine(out) + UDP-alpha-D-galactose(in) = UDP-N-acetyl-alpha-D-glucosamine(in) + UDP-alpha-D-galactose(out)
3. a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + UDP-N-acetyl-alpha-D-glucosamine = a 6-(N-acetyl-alpha-D-glucosaminyl)-1-(1,2-diacyl-sn-glycero-3-phospho)-1D-myo-inositol + UDP + H(+)
Catalysed by GALT, SLC35A2, PIGAinner side of the membrane, outer side of the membrane
(2R)-3-phospho-glyceroyl phosphateReach from here →
1. alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose = alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose
2. (2R)-3-phospho-glyceroyl phosphate + alpha-D-glucose 1-phosphate = alpha-D-glucose 1,6-bisphosphate + (2R)-3-phosphoglycerate + H(+)
3. ATP:3-phospho-D-glycerate 1-phosphotransferase
Catalysed by GALT, PGM2L1, PGK1, PGK2 and 1 morecytosolOne of 2 routes
beta-D-fructose 6-phosphateReach from here →
1. alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose = alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose
2. alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate
3. alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate
Catalysed by GALT, PGM1, PGM2, GPI
an N-acylsphing-4-enine 1-phosphateReach from here →
1. an N-acylsphing-4-enine + UDP-alpha-D-glucose = a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + UDP + H(+)
2. a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + H2O = an N-acylsphing-4-enine + D-glucose
3. an N-acylsphing-4-enine + ATP = an N-acylsphing-4-enine 1-phosphate + ADP + H(+)
Catalysed by UGCG, GBA1, GBA3, GBA2 and 2 more
sphing-4-enineReach from here →
1. an N-acylsphing-4-enine + UDP-alpha-D-glucose = a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + UDP + H(+)
2. a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + H2O = an N-acylsphing-4-enine + D-glucose
3. acyl-CoA:sphingosine N-acyltransferase
Catalysed by UGCG, GBA1, GBA3, GBA2 and 4 moreGolgi apparatusOne of 5 routes
N-acetyl-alpha-D-glucosamine 1-phosphateReach from here →
1. alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose = alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose
2. UDP-N-acetyl-alpha-D-glucosamine(out) + UDP-alpha-D-galactose(in) = UDP-N-acetyl-alpha-D-glucosamine(in) + UDP-alpha-D-galactose(out)
3. UDP-N-acetyl-alpha-D-glucosamine + H2O = N-acetyl-alpha-D-glucosamine 1-phosphate + UMP + 2 H(+)
Catalysed by GALT, SLC35A2, ENPP3inner side of the membrane, outer side of the membrane
(2R)-2-phosphoglycerateReach from here →
1. alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose = alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose
2. (2R)-3-phospho-glyceroyl phosphate + alpha-D-glucose 1-phosphate = alpha-D-glucose 1,6-bisphosphate + (2R)-3-phosphoglycerate + H(+)
3. D-phosphoglycerate 2,3-phosphomutase
Catalysed by GALT, PGM2L1, BPGM, PGAM2 and 2 morecytosolOne of 2 routes
an acyl-CoAReach from here →
1. an N-acylsphing-4-enine + UDP-alpha-D-glucose = a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + UDP + H(+)
2. a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + H2O = an N-acylsphing-4-enine + D-glucose
3. acyl-CoA:sphingosine N-acyltransferase
Catalysed by UGCG, GBA1, GBA3, GBA2 and 4 moreGolgi apparatusOne of 2 routes
a neolactoside IV(3)-alpha-NeuAc-nLc4Cer(d18:1(4E))Reach from here →
1. alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose = alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose
2. a beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + UDP-alpha-D-galactose = a neolactoside nLc4Cer(d18:1(4E)) + UDP + H(+)
3. ST3 beta-galactoside alpha-2,3-sialyltransferase (CMP-N-acetylneuraminate)
Catalysed by GALT, B4GALT3, B4GALT4, B4GALT1 and 1 morecytosolOne of 2 routes
a ganglioside GM3 (d18:1(4E))Reach from here →
1. an N-acylsphing-4-enine + UDP-alpha-D-glucose = a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + UDP + H(+)
2. a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + UDP-alpha-D-galactose = a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + UDP + H(+)
3. ST3 beta-galactoside alpha-2,3-sialyltransferase (CMP-N-acetylneuraminate)
Catalysed by UGCG, B4GALT5, B4GALT6, ST3GAL5cytosolOne of 3 routes
D-glucose 6-phosphateReach from here →
1. an N-acylsphing-4-enine + UDP-alpha-D-glucose = a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + UDP + H(+)
2. a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + H2O = an N-acylsphing-4-enine + D-glucose
3. D-glucose + ADP = D-glucose 6-phosphate + AMP + H(+)
Catalysed by UGCG, GBA1, GBA3, GBA2 and 1 moreOne of 2 routes
an all-trans-retinyl esterReach from here →
1. an N-acylsphing-4-enine + UDP-alpha-D-glucose = a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + UDP + H(+)
2. a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + H2O = beta-D-glucosyl-(1<->1)-sphing-4-enine + a fatty acid
3. an all-trans-retinyl ester + H2O = 11-cis-retinol + a fatty acid + H(+)
Catalysed by UGCG, ASAH1, RPE65
beta-D-glucosyl-N-octanoylsphing-4E-enineReach from here →
1. an N-acylsphing-4-enine + UDP-alpha-D-glucose = a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + UDP + H(+)
2. a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + cholesterol = cholesteryl 3-beta-D-glucoside + an N-acylsphing-4-enine
3. beta-D-glucosyl-N-octanoylsphing-4E-enine + cholesterol = N-octanoylsphing-4-enine + cholesteryl 3-beta-D-glucoside
Catalysed by UGCG, GBA1, GBA2
CHEBI:67119Reach from here →
1. alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose = alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose
2. alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose = alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose
3. UDP-glucose:alpha-D-galactose-1-phosphate uridylyltransferase
Catalysed by GALTcytosolOne of 2 routes
a ganglioside GM2 (d18:1(4E))Reach from here →
1. alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose = alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose
2. a ganglioside GM2 (d18:1(4E)) + UDP-alpha-D-galactose = a ganglioside GM1 (d18:1(4E)) + UDP + H(+)
3. beta-galactosidase (GM1)
Catalysed by GALT, B3GALT4, LCT, GLB1 and 2 morecytosolOne of 5 routes
an N-acylsphing-4-enine 1-phosphoethanolamineReach from here →
1. an N-acylsphing-4-enine + UDP-alpha-D-glucose = a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + UDP + H(+)
2. a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + H2O = an N-acylsphing-4-enine + D-glucose
3. an N-acylsphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = an N-acylsphing-4-enine 1-phosphoethanolamine + a 1,2-diacyl-sn-glycerol
Catalysed by UGCG, GBA1, GBA3, GBA2 and 3 more
an N-acyl-1-beta-D-(3-O-sulfo)-galactosyl-sphing-4-enineReach from here →
1. alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose = alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose
2. an N-acylsphing-4-enine + UDP-alpha-D-galactose = a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + UDP + H(+)
3. a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + 3'-phosphoadenylyl sulfate = an N-acyl-1-beta-D-(3-O-sulfo)-galactosyl-sphing-4-enine + adenosine 3',5'-bisphosphate + H(+)
Catalysed by GALT, UGT8, GAL3ST1
beta-D-glucosyl-N-dodecanoylsphing-4-enineReach from here →
1. an N-acylsphing-4-enine + UDP-alpha-D-glucose = a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + UDP + H(+)
2. a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + cholesterol = cholesteryl 3-beta-D-glucoside + an N-acylsphing-4-enine
3. beta-D-glucosyl-N-dodecanoylsphing-4-enine + cholesterol = N-dodecanoylsphing-4-enine + cholesteryl 3-beta-D-glucoside
Catalysed by UGCG, GBA1, GBA2
beta-D-glucosyl-(1<->1')-N-(15Z-tetracosenoyl)-sphing-4-enineReach from here →
1. an N-acylsphing-4-enine + UDP-alpha-D-glucose = a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + UDP + H(+)
2. a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + cholesterol = cholesteryl 3-beta-D-glucoside + an N-acylsphing-4-enine
3. beta-D-glucosyl-(1<->1')-N-(15Z-tetracosenoyl)-sphing-4-enine + cholesterol = N-(15Z-tetracosenoyl)-sphing-4-enine + cholesteryl 3-beta-D-glucoside
Catalysed by UGCG, GBA1, GBA2
a neolactoside III(3)-alpha-Fuc-nLc4Cer(d18:1(4E))Reach from here →
1. alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose = alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose
2. a beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + UDP-alpha-D-galactose = a neolactoside nLc4Cer(d18:1(4E)) + UDP + H(+)
3. a neolactoside nLc4Cer(d18:1(4E)) + GDP-beta-L-fucose = a neolactoside III(3)-alpha-Fuc-nLc4Cer(d18:1(4E)) + GDP + H(+)
Catalysed by GALT, B4GALT3, B4GALT4, B4GALT1 and 1 more
a 1,3-diacyl-sn-glycerolReach from here →
1. an N-acylsphing-4-enine + UDP-alpha-D-glucose = a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + UDP + H(+)
2. a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + H2O = beta-D-glucosyl-(1<->1)-sphing-4-enine + a fatty acid
3. a 1,3-diacyl-sn-glycerol + H2O = a 1-acyl-sn-glycerol + a fatty acid + H(+)
Catalysed by UGCG, ASAH1, ABHD11
a fatty acyl-CoAReach from here →
1. an N-acylsphing-4-enine + UDP-alpha-D-glucose = a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + UDP + H(+)
2. a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + H2O = beta-D-glucosyl-(1<->1)-sphing-4-enine + a fatty acid
3. a fatty acid + ATP + CoA = a fatty acyl-CoA + AMP + diphosphate
Catalysed by UGCG, ASAH1, ACSL3
beta-D-3-sulfogalactosyl-(1->4)-beta-D-glucosyl-(1<->1')-N-acylsphing-4-enineReach from here →
1. an N-acylsphing-4-enine + UDP-alpha-D-glucose = a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + UDP + H(+)
2. a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + UDP-alpha-D-galactose = a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + UDP + H(+)
3. a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + 3'-phosphoadenylyl sulfate = beta-D-3-sulfogalactosyl-(1->4)-beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + adenosine 3',5'-bisphosphate + H(+)
Catalysed by UGCG, B4GALT5, B4GALT6, GAL3ST1
a ganglioside GD1a (d18:1(4E))Reach from here →
1. alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose = alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose
2. a ganglioside GM2 (d18:1(4E)) + UDP-alpha-D-galactose = a ganglioside GM1 (d18:1(4E)) + UDP + H(+)
3. beta-galactoside alpha-2,3-sialyltransferase (CMP-N-acetylneuraminate)
Catalysed by GALT, B3GALT4, ST3GAL1, ST3GAL4 and 1 morecytosolOne of 3 routes
a ganglioside GT1b (d18:1(4E))Reach from here →
1. alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose = alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose
2. a ganglioside GD2 (d18:1(4E)) + UDP-alpha-D-galactose = a ganglioside GD1b (d18:1(4E)) + UDP + H(+)
3. beta-galactoside alpha-2,3-sialyltransferase (CMP-N-acetylneuraminate)
Catalysed by GALT, B3GALT4, ST3GAL1, ST3GAL4 and 1 morecytosolOne of 3 routes
a ganglioside GM4 (d18:1(4E))Reach from here →
1. alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose = alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose
2. an N-acylsphing-4-enine + UDP-alpha-D-galactose = a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + UDP + H(+)
3. a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + CMP-N-acetyl-beta-neuraminate = a ganglioside GM4 (d18:1(4E)) + CMP + H(+)
Catalysed by GALT, UGT8, ST3GAL5
a ganglioside GD2 (d18:1(4E))Reach from here →
1. alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose = alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose
2. a ganglioside GD2 (d18:1(4E)) + UDP-alpha-D-galactose = a ganglioside GD1b (d18:1(4E)) + UDP + H(+)
3. Beta-Galactosidase, Lysosomal
Catalysed by GALT, B3GALT4, GLB1lysosomeOne of 2 routes
a ganglioside GM1b (d18:1(4E))Reach from here →
1. alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose = alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose
2. a ganglioside GA2 (d18:1(4E)) + UDP-alpha-D-galactose = a ganglioside GA1 (d18:1(4E)) + UDP + H(+)
3. a ganglioside GA1 (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate = a ganglioside GM1b (d18:1(4E)) + CMP + H(+)
Catalysed by GALT, B3GALT4, ST3GAL1, ST3GAL4 and 1 more
a ganglioside Fuc-GM1 (d18:1(4E))Reach from here →
1. alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose = alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose
2. a ganglioside GM2 (d18:1(4E)) + UDP-alpha-D-galactose = a ganglioside GM1 (d18:1(4E)) + UDP + H(+)
3. a ganglioside GM1 (d18:1(4E)) + GDP-beta-L-fucose = a ganglioside Fuc-GM1 (d18:1(4E)) + GDP + H(+)
Catalysed by GALT, B3GALT4, FUT2
a ganglioside GM2Reach from here →
1. alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose = alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose
2. UDP-N-acetyl-alpha-D-galactosamine(out) + UDP-alpha-D-galactose(in) = UDP-N-acetyl-alpha-D-galactosamine(in) + UDP-alpha-D-galactose(out)
3. a ganglioside GM3 + UDP-N-acetyl-alpha-D-galactosamine = a ganglioside GM2 + UDP + H(+)
Catalysed by GALT, SLC35A2, B4GALNT1inner side of the membrane, outer side of the membrane
a ganglioside GD2Reach from here →
1. alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose = alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose
2. UDP-N-acetyl-alpha-D-galactosamine(out) + UDP-alpha-D-galactose(in) = UDP-N-acetyl-alpha-D-galactosamine(in) + UDP-alpha-D-galactose(out)
3. a ganglioside GD3 + UDP-N-acetyl-alpha-D-galactosamine = a ganglioside GD2 + UDP + H(+)
Catalysed by GALT, SLC35A2, B4GALNT1inner side of the membrane, outer side of the membrane
a ganglioside GD1aReach from here →
1. alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose = alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose
2. a ganglioside GM2 + UDP-alpha-D-galactose = a ganglioside GM1 + UDP + H(+)
3. a ganglioside GM1 + CMP-N-acetyl-beta-neuraminate = a ganglioside GD1a + CMP + H(+)
Catalysed by GALT, B3GALT4, ST3GAL1, ST3GAL2
N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1<->1')-ceramideReach from here →
1. alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose = alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose
2. an N-acyl-sphingoid base + UDP-alpha-D-galactose = a beta-D-Gal-(1<->1')-ceramide + UDP + H(+)
3. a beta-D-Gal-(1<->1')-ceramide + CMP-N-acetyl-beta-neuraminate = N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1<->1')-ceramide + CMP + H(+)
Catalysed by GALT, UGT8, ST3GAL5
1,2-dihexadecanoyl-sn-glycerolReach from here →
1. an N-acylsphing-4-enine + UDP-alpha-D-glucose = a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + UDP + H(+)
2. a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + H2O = an N-acylsphing-4-enine + D-glucose
3. 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + an N-acylsphing-4-enine = 1,2-dihexadecanoyl-sn-glycerol + a sphingomyelin
Catalysed by UGCG, GBA1, GBA3, GBA2 and 1 more
a ganglioside GalNAc-GD1aReach from here →
1. alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose = alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose
2. UDP-N-acetyl-alpha-D-galactosamine(out) + UDP-alpha-D-galactose(in) = UDP-N-acetyl-alpha-D-galactosamine(in) + UDP-alpha-D-galactose(out)
3. a ganglioside GD1a + UDP-N-acetyl-alpha-D-galactosamine = a ganglioside GalNAc-GD1a + UDP + H(+)
Catalysed by GALT, SLC35A2, B4GALNT1inner side of the membrane, outer side of the membrane
1-(3-O-sulfo-beta-D-galactosyl)-ceramideReach from here →
1. alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose = alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose
2. an N-acyl-sphingoid base + UDP-alpha-D-galactose = a beta-D-Gal-(1<->1')-ceramide + UDP + H(+)
3. a beta-D-Gal-(1<->1')-ceramide + 3'-phosphoadenylyl sulfate = 1-(3-O-sulfo-beta-D-galactosyl)-ceramide + adenosine 3',5'-bisphosphate + H(+)
Catalysed by GALT, UGT8, GAL3ST1
1-(9Z-octadecenoyl)-2-acyl-sn-3-glycerolReach from here →
1. an N-acylsphing-4-enine + UDP-alpha-D-glucose = a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + UDP + H(+)
2. a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + H2O = an N-acylsphing-4-enine + D-glucose
3. 1-(9Z-octadecenoyl)-2-acyl-sn-3-glycerol + a sphingomyelin = a 1-(9Z-octadecenoyl)-2-acyl-sn-glycero-3-phosphocholine + an N-acylsphing-4-enine
Catalysed by UGCG, GBA1, GBA3, GBA2 and 2 more
an N-acyl-sphingoid baseReach from here →
1. alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose = alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose
2. an N-acyl-sphingoid base + UDP-alpha-D-galactose = a beta-D-Gal-(1<->1')-ceramide + UDP + H(+)
3. an N-acyl-sphingoid base + UDP-alpha-D-galactose = a beta-D-Gal-(1<->1')-ceramide + UDP + H(+)
Catalysed by GALT, UGT8
beta-D-glucosyl-(1<->1')-N-hexadecanoylsphing-4-enineReach from here →
1. an N-acylsphing-4-enine + UDP-alpha-D-glucose = a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + UDP + H(+)
2. a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + cholesterol = cholesteryl 3-beta-D-glucoside + an N-acylsphing-4-enine
3. beta-D-glucosyl-(1<->1')-N-hexadecanoylsphing-4-enine + cholesterol = cholesteryl 3-beta-D-glucoside + N-hexadecanoylsphing-4-enine
Catalysed by UGCG, GBA1, GBA2
beta-D-glucosyl-(1<->1)-N-octadecanoylsphing-4-enineReach from here →
1. an N-acylsphing-4-enine + UDP-alpha-D-glucose = a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + UDP + H(+)
2. a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + cholesterol = cholesteryl 3-beta-D-glucoside + an N-acylsphing-4-enine
3. beta-D-glucosyl-(1<->1)-N-octadecanoylsphing-4-enine + cholesterol = cholesteryl 3-beta-D-glucoside + N-octadecanoylsphing-4-enine
Catalysed by UGCG, GBA1, GBA2
a ganglioside GA1Reach from here →
1. alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose = alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose
2. a ganglioside GM2 + UDP-alpha-D-galactose = a ganglioside GM1 + UDP + H(+)
3. a ganglioside GM1 + H2O = a ganglioside GA1 + N-acetylneuraminate
Catalysed by GALT, B3GALT4, NEU3, NEU2
beta-D-galactosyl-(1->4)-[alpha-L-fucosyl-(1->3)]-D-glucoseReach from here →
1. alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose = alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose
2. D-glucose + UDP-alpha-D-galactose = lactose + UDP + H(+)
3. lactose + GDP-beta-L-fucose = beta-D-galactosyl-(1->4)-[alpha-L-fucosyl-(1->3)]-D-glucose + GDP + H(+)
Catalysed by GALT, B4GALT2, B4GALT1, FUT3 and 1 more
a ganglioside GA2Reach from here →
1. alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose = alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose
2. a beta-D-glucosylceramide + UDP-alpha-D-galactose = a beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide + UDP + H(+)
3. a beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide + UDP-N-acetyl-alpha-D-galactosamine = a ganglioside GA2 + UDP + H(+)
Catalysed by GALT, B4GALT3, B4GALT1, B4GALNT1One of 2 routes
a ganglioside Fuc-GM1Reach from here →
1. alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose = alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose
2. a ganglioside GM2 + UDP-alpha-D-galactose = a ganglioside GM1 + UDP + H(+)
3. a ganglioside GM1 + GDP-beta-L-fucose = a ganglioside Fuc-GM1 + GDP + H(+)
Catalysed by GALT, B3GALT4, FUT1, FUT2