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Proteins/UNIPROT:P37287
Catalytic subunit of the glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex that catalyzes the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol and participates in the first step of GPI biosynthesis..
Function from UniProtKB (P37287), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
5 rows
25 statements
25 statements · 5 reference databases · Subject: PIGA · Sources: Hetionet, Human-GEM, Reactome, Rhea, WikiPathways
3 reactions
1-phosphatidyl-1D-myo-inositol+CHEBI:16264proton+a 6-(N-acetyl-alpha-D-glucosaminyl)-1-(1,2-diacyl-sn-glycero-3-phospho)-1D-myo-inositol+UDP
Catalysed by PIGA & PIGH & PIGC & PIGQ or PYURF or PIGP or PIGY
Reaction pageLeft to rightBalance undeterminableEC 2.4.1.198endoplasmic reticulum
Human-GEM MAR07185CC BY 4.0Reference data
3 names
Resolves to: PIGA
Reaction pageLeft to rightBalance undeterminableEC 2.4.1.198cytosol
Human-GEM MAR08379CC BY 4.0Reference data
a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol)+UDP-N-acetyl-alpha-D-glucosaminea 6-(N-acetyl-alpha-D-glucosaminyl)-1-(1,2-diacyl-sn-glycero-3-phospho)-1D-myo-inositol+UDP+hydron
Catalysed by PIGA
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:14789CC BY 4.0Reference data