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a neolactoside IV(3)-alpha-NeuAc-nLc4Cer(d18:1(4E))

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

Inferred

Every route here is a hypothesis drawn from reference reactions (Rhea and Human-GEM), not a finding. Currency species such as water, ATP and NAD(H) never form a step. Evidence key

7 compounds within 3 steps: 2 in 1, 3 in 2, 2 in 3

Does it reach a compound?

One step

a neolactoside nLc4Cer(d18:1(4E))Reach from here →
1. a neolactoside IV(3)-alpha-NeuAc-nLc4Cer(d18:1(4E)) + H2O = a neolactoside nLc4Cer(d18:1(4E)) + N-acetylneuraminate
Catalysed by NEU2
N-acetylneuraminateReach from here →
1. a neolactoside IV(3)-alpha-NeuAc-nLc4Cer(d18:1(4E)) + H2O = a neolactoside nLc4Cer(d18:1(4E)) + N-acetylneuraminate
Catalysed by NEU2

Two steps

a neolactoside IV(3)-beta-GlcNAc-nLc4Cer(d18:1(4E))Reach from here →
1. a neolactoside IV(3)-alpha-NeuAc-nLc4Cer(d18:1(4E)) + H2O = a neolactoside nLc4Cer(d18:1(4E)) + N-acetylneuraminate
2. a neolactoside nLc4Cer(d18:1(4E)) + UDP-N-acetyl-alpha-D-glucosamine = a neolactoside IV(3)-beta-GlcNAc-nLc4Cer(d18:1(4E)) + UDP + H(+)
Catalysed by NEU2, B3GNT5
a neolactoside IV(2)-alpha-Fuc-nLc4Cer(d18:1(4E))Reach from here →
1. a neolactoside IV(3)-alpha-NeuAc-nLc4Cer(d18:1(4E)) + H2O = a neolactoside nLc4Cer(d18:1(4E)) + N-acetylneuraminate
2. a neolactoside nLc4Cer(d18:1(4E)) + GDP-beta-L-fucose = a neolactoside IV(2)-alpha-Fuc-nLc4Cer(d18:1(4E)) + GDP + H(+)
Catalysed by NEU2, FUT1, FUT2

Three steps

L-fucoseReach from here →
Catalysed by NEU2, FUT1, FUT2, FUCA1
a neolactoside IV(3)-beta-[Gal-beta-(1->3)-GlcNAc]-nLc4Cer(d18:1(4E))Reach from here →

a neolactoside III(3)-alpha-Fuc-nLc4Cer(d18:1(4E))Reach from here →

a neolactoside IV(3)-alpha-NeuAc-nLc4Cer(d18:1(4E)) + H2O = a neolactoside nLc4Cer(d18:1(4E)) + N-acetylneuraminate
a neolactoside nLc4Cer(d18:1(4E)) + GDP-beta-L-fucose = a neolactoside III(3)-alpha-Fuc-nLc4Cer(d18:1(4E)) + GDP + H(+)

Catalysed by NEU2, FUT5

a neolactoside IV(3)-beta-GlcNAc-nLc4Cer(d18:1(4E)) + UDP-alpha-D-galactose = a neolactoside IV(3)-beta-[Gal-beta-(1->3)-GlcNAc]-nLc4Cer(d18:1(4E)) + UDP + H(+)

Catalysed by NEU2, B3GNT5, B3GALT2