Compound

beta-D-fructose 6-phosphate

An organophosphate oxoanion that is the dianion of β-D-fructofuranose 6-phosphate arising from deprotonation of the phosphate OH groups.

Definition from ChEBI (CHEBI:57634), read 2026-09-23. CC BY 4.0.

CHEBI:57634ChEBI

Open in the graph

Structure

2D depiction · 3D model shown

Loading the model…

A generated conformer of beta-D-fructose 6-phosphate — one low-energy arrangement PubChem computed, not a measured structure. Hydrogens are not drawn; the formula counts them.

Class: Organic compound, anion
Formula: C6H11O9P
Mass: 258.119 g/mol
Charge: -2
InChIKey: BGWGXPAPYGQALX-ARQDHWQXSA-L
SMILES: O=P([O-])([O-])OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O
Look it up: ChEBI PubChem By InChIKey

Identity from ChEBI, geometry from PubChem. Not evidence.

What it touches on the way

Mechanistic reach

13 entities

13 entities reached.

0 reported hops13 assembled from the scaffold

Show the remaining 1

GNPDA1ProteinUNIPROT:P46926substrate ofInferred only4 paths4 endpoints

What the reference databases state

Chemical structure

beta-D-fructose 6-phosphate has the functional parent beta-D-fructoseCompoundChEBI CHEBI:57634Inferred only

Statements

26 statements

26 statements · 1 reference database · Subject: beta-D-fructose 6-phosphate · Sources: Rhea

Order

beta-D-fructose 6-phosphate is converted to alpha-D-glucosamine 6-phosphateCompoundRhea RHEA:12172Inferred only
alpha-D-glucosamine 6-phosphate is converted to beta-D-fructose 6-phosphateCompoundRhea RHEA:12172Inferred only
alpha-D-glucose 6-phosphate is converted to beta-D-fructose 6-phosphateCompoundRhea RHEA:11816Inferred only
beta-D-fructose 6-phosphate is converted to alpha-D-glucose 6-phosphateCompoundRhea RHEA:11816Inferred only
beta-D-fructose 1,6-bisphosphate is converted to beta-D-fructose 6-phosphateCompoundRhea RHEA:20105Inferred only
beta-D-fructose 6-phosphate is converted to beta-D-fructose 1,6-bisphosphateCompoundRhea RHEA:11064Inferred only
beta-D-fructose 6-phosphate is converted to beta-D-fructose 1,6-bisphosphateCompoundRhea RHEA:13613Inferred only
beta-D-fructose 6-phosphate is converted to beta-D-fructose 1,6-bisphosphateCompoundRhea RHEA:16109Inferred only
beta-D-fructose 6-phosphate is converted to beta-D-fructose 1,6-bisphosphateCompoundRhea RHEA:20105Inferred only
beta-D-fructose 1,6-bisphosphate is converted to beta-D-fructose 6-phosphateCompoundRhea RHEA:11064Inferred only
beta-D-fructose 1,6-bisphosphate is converted to beta-D-fructose 6-phosphateCompoundRhea RHEA:13613Inferred only
beta-D-fructose 6-phosphate is a substrate of DCPH1ProteinRhea RHEA:28002Inferred only

Show the remaining 14

beta-D-fructose 6-phosphate is a substrate of FBP1ProteinRhea RHEA:11064Inferred only
beta-D-fructose 6-phosphate is a substrate of FBP2ProteinRhea RHEA:11064Inferred only
beta-D-fructose 6-phosphate is a substrate of GNPDA1ProteinRhea RHEA:12172Inferred only
beta-D-fructose 6-phosphate is a substrate of GNPDA2ProteinRhea RHEA:12172Inferred only
beta-D-fructose 6-phosphate is a substrate of GPIProteinRhea RHEA:11816Inferred only
beta-D-fructose 6-phosphate is a substrate of GPIProteinRhea RHEA:85579Inferred only
beta-D-fructose 6-phosphate is a substrate of PFKFB1ProteinRhea RHEA:15653Inferred only
beta-D-fructose 6-phosphate is a substrate of PFKFB2ProteinRhea RHEA:15653Inferred only
beta-D-fructose 6-phosphate is a substrate of PFKFB3ProteinRhea RHEA:15653Inferred only
beta-D-fructose 6-phosphate is a substrate of PFKFB4ProteinRhea RHEA:15653Inferred only
beta-D-fructose 6-phosphate is a substrate of PFKLProteinRhea RHEA:16109Inferred only
beta-D-fructose 6-phosphate is a substrate of PFKMProteinRhea RHEA:16109Inferred only
beta-D-fructose 6-phosphate is a substrate of PFKPProteinRhea RHEA:16109Inferred only
beta-D-fructose 6-phosphate is a substrate of TALDO1ProteinRhea RHEA:17053Inferred only

Reactions

19 reactions

beta-D-fructose 1,6-bisphosphate+waterbeta-D-fructose 6-phosphate+hydrogenphosphate
Catalysed by FBP2 or FBP1
Reaction pageDirection not assertedBalanced
Rhea RHEA:11064CC BY 4.0Reference data
alpha-D-glucose 6-phosphatebeta-D-fructose 6-phosphate
Catalysed by GPI
Reaction pageReversibleBalanced
Rhea RHEA:11816CC BY 4.0Reference data
alpha-D-glucosamine 6-phosphate+waterbeta-D-fructose 6-phosphate+ammonium
Catalysed by GNPDA1 or GNPDA2
Reaction pageReversibleBalanced
Rhea RHEA:12172CC BY 4.0Reference data
beta-D-fructose 6-phosphate+diphosphate(3-)beta-D-fructose 1,6-bisphosphate+hydrogenphosphate+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:13613CC BY 4.0Reference data
beta-D-fructose 6-phosphate+ATP(4-)CHEBI:58579+ADP(3-)+hydron
Catalysed by PFKFB2 or PFKFB1 or PFKFB3 or PFKFB4
Reaction pageLeft to rightBalanced
Rhea RHEA:15653CC BY 4.0Reference data
beta-D-fructose 6-phosphate+ATP(4-)beta-D-fructose 1,6-bisphosphate+ADP(3-)+hydron
Catalysed by PFKM or PFKL or PFKP
Reaction pageLeft to rightBalanced
Rhea RHEA:16109CC BY 4.0Reference data
D-sedoheptulose 7-phosphate+D-glyceraldehyde 3-phosphateD-erythrose 4-phosphate+beta-D-fructose 6-phosphate
Catalysed by TALDO1
Reaction pageReversibleBalanced
Rhea RHEA:17053CC BY 4.0Reference data
CHEBI:58579+waterbeta-D-fructose 6-phosphate+hydrogenphosphate
Catalysed by PFKFB2 or PFKFB1 or PFKFB3 or PFKFB4 or TIGAR
Reaction pageLeft to rightBalanced
Rhea RHEA:17289CC BY 4.0Reference data
CHEBI:61381+NAD(1-)beta-D-fructose 6-phosphate+NADH(2-)+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:19661CC BY 4.0Reference data
CHEBI:60084+NAD(1-)beta-D-fructose 6-phosphate+NADH(2-)+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:19837CC BY 4.0Reference data
beta-D-fructose 6-phosphate+ADP(3-)beta-D-fructose 1,6-bisphosphate+AMP+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:20105CC BY 4.0Reference data
beta-D-fructose 6-phosphate+UDP-alpha-D-glucoseCHEBI:57723+UDP+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:22172CC BY 4.0Reference data

Show the remaining 7

Other names

6 names

Resolves to: beta-D-fructose 6-phosphate

Also called: 6-O-phosphonato-beta-D-fructofuranose6-O-phosphonato-β-D-fructofuranosebeta-D-fructofuranose 6-phosphate dianionβ-D-fructofuranose 6-phosphate dianion
Systematic name: beta-D-fructofuranose 6-phosphateβ-D-fructofuranose 6-phosphate