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Reference

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a ganglioside GA1

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

Inferred

Every route here is a hypothesis drawn from reference reactions (Rhea and Human-GEM), not a finding. Currency species such as water, ATP and NAD(H) never form a step. Evidence key

6 compounds within 3 steps: 3 in 1, 2 in 2, 1 in 3

Does it reach a compound?

One step

a ganglioside beta-D-GlcNAc-(1->6)-GA1Reach from here →
1. a ganglioside GA1 + UDP-N-acetyl-alpha-D-glucosamine = a ganglioside beta-D-GlcNAc-(1->6)-GA1 + UDP + H(+)
Catalysed by GCNT1
a ganglioside GM1bReach from here →
1. a ganglioside GA1 + CMP-N-acetyl-beta-neuraminate = a ganglioside GM1b + CMP + H(+)
Catalysed by ST3GAL1, ST3GAL2
a ganglioside Fuc-GA1Reach from here →
1. a ganglioside GA1 + GDP-beta-L-fucose = a ganglioside Fuc-GA1 + GDP + H(+)
Catalysed by FUT1, FUT2

Two steps

an 8-O-sulfo-ganglioside GM1bReach from here →
1. a ganglioside GA1 + CMP-N-acetyl-beta-neuraminate = a ganglioside GM1b + CMP + H(+)
2. a ganglioside GM1b + 3'-phosphoadenylyl sulfate = an 8-O-sulfo-ganglioside GM1b + adenosine 3',5'-bisphosphate + H(+)
Catalysed by ST3GAL1, ST3GAL2, WSCD1
a ganglioside GD1cReach from here →
1. a ganglioside GA1 + CMP-N-acetyl-beta-neuraminate = a ganglioside GM1b + CMP + H(+)
2. a ganglioside GM1b + CMP-N-acetyl-beta-neuraminate = a ganglioside GD1c + CMP + H(+)
Catalysed by ST3GAL1, ST3GAL2, ST8SIA6

Three steps

CMP-N-acetyl-beta-neuraminateReach from here →
Catalysed by ST3GAL1, ST3GAL2, ST8SIA6