Compound
a neolactoside IV(3)-alpha-NeuAc-nLc4Cer(d18:1(4E))
A carbohydrate acid derivative anion that is the conjugate base of α-N-acetylneuraminosyl-(2→3)-β-D-galactosyl-(1→4)-N-acetyl-β-D-glucosaminyl-(1→3)-β-D-galactosyl-(1→4)-β-D-glucosylceramide.
Definition from ChEBI (CHEBI:58665), read 2026-09-23. CC BY 4.0.
Structure
- Class
- Organic compound, anion
- Formula
- C56H95N3O31R
- Mass
- 1306.355 g/mol
- Charge
- -1
- SMILES
- *C(=O)N[C@@H](CO[C@@H]1O[C@H](CO)[C@@H](O[C@@H]2O[C@H](CO)[C@H](O)[C@H](O[C@@H]3O[C@H](CO)[C@@H](O[C@@H]4O[C@H](CO)[C@H](O)[C@H](O[C@]5(C(=O)[O-])C[C@H](O)[C@@H](NC(C)=O)[C@]([H])([C@H](O)[C@H](O)CO)O5)[C@H]4O)[C@H](O)[C@H]3NC(C)=O)[C@H]2O)[C@H](O)[C@H]1O)[C@H](O)/C=C/CCCCCCCCCCCCC
- Look it up
- ChEBI
Identity from ChEBI. Not evidence.
What it touches on the way
Mechanistic reach
8 entities
8 entities reached.
0 reported hops8 assembled from the scaffold
- ST3GAL4ProteinUNIPROT:Q11206substrate ofInferred only38 paths38 endpoints
- ST3GAL6ProteinUNIPROT:Q9Y274substrate ofInferred only17 paths17 endpoints
- NEU2ProteinUNIPROT:Q9Y3R4substrate ofInferred only14 paths14 endpoints
- ST8SIA5ProteinUNIPROT:O15466substrate ofInferred only13 paths13 endpoints
- ST8SIA1ProteinUNIPROT:Q92185substrate ofInferred only8 paths8 endpoints
- FUT4ProteinUNIPROT:P22083substrate ofInferred only2 paths2 endpoints
- FUT7ProteinUNIPROT:Q11130substrate ofInferred only2 paths2 endpoints
- FUT9ProteinUNIPROT:Q9Y231substrate ofInferred only2 paths1 endpoint
What the reference databases state
Statements
10 statements
10 statements · 2 reference databases · Subject: a neolactoside IV(3)-alpha-NeuAc-nLc4Cer(d18:1(4E)) · Sources: Human-GEM, Rhea
- CMP-N-acetyl-beta-neuraminate is converted to a neolactoside IV(3)-alpha-NeuAc-nLc4Cer(d18:1(4E))CompoundHuman-GEM MAR08325Inferred only
- a neolactoside IV(3)-alpha-NeuAc-nLc4Cer(d18:1(4E)) is a substrate of FUT4ProteinHuman-GEM MAR00878Inferred only
- a neolactoside IV(3)-alpha-NeuAc-nLc4Cer(d18:1(4E)) is a substrate of FUT7ProteinHuman-GEM MAR00878Inferred only
- a neolactoside IV(3)-alpha-NeuAc-nLc4Cer(d18:1(4E)) is a substrate of FUT9ProteinHuman-GEM MAR00878Inferred only
- a neolactoside IV(3)-alpha-NeuAc-nLc4Cer(d18:1(4E)) is a substrate of FUT9ProteinHuman-GEM MAR08326Inferred only
- a neolactoside IV(3)-alpha-NeuAc-nLc4Cer(d18:1(4E)) is a substrate of NEU2ProteinRhea RHEA:47852Inferred only
- a neolactoside IV(3)-alpha-NeuAc-nLc4Cer(d18:1(4E)) is a substrate of ST3GAL4ProteinRhea RHEA:18913Inferred only
- a neolactoside IV(3)-alpha-NeuAc-nLc4Cer(d18:1(4E)) is a substrate of ST3GAL6ProteinRhea RHEA:18913Inferred only
- a neolactoside IV(3)-alpha-NeuAc-nLc4Cer(d18:1(4E)) is a substrate of ST8SIA1ProteinHuman-GEM MAR00877Inferred only
- a neolactoside IV(3)-alpha-NeuAc-nLc4Cer(d18:1(4E)) is a substrate of ST8SIA5ProteinHuman-GEM MAR08327Inferred only
Reactions
9 reactions
CMP-N-acetyl-beta-neuraminate+a neolactoside nLc4Cer(d18:1(4E))cytidine 5'-monophosphate+proton+a neolactoside IV(3)-alpha-NeuAc-nLc4Cer(d18:1(4E))
Catalysed by ST3GAL6
Reaction pageLeft to rightBalance undeterminableEC 2.4.3.6GO:0005829
Human-GEM MAR00876CC BY 4.0Reference data
CMP-N-acetyl-beta-neuraminate+a neolactoside IV(3)-alpha-NeuAc-nLc4Cer(d18:1(4E))MAM00744c+cytidine 5'-monophosphate+proton
Catalysed by ST8SIA1
Reaction pageLeft to rightBalance undeterminableEC 2.4.3.8GO:0005829
Human-GEM MAR00877CC BY 4.0Reference data
MAM01950c+a neolactoside IV(3)-alpha-NeuAc-nLc4Cer(d18:1(4E))GDP+proton+MAM02199c
Catalysed by FUT9 or FUT7 or FUT4
Reaction pageLeft to rightBalance undeterminableEC 2.4.1.152, 2.4.1.-GO:0005829
Human-GEM MAR00878CC BY 4.0Reference data
CMP-N-acetyl-beta-neuraminate+MAM02330gcytidine 5'-monophosphate+proton+a neolactoside IV(3)-alpha-NeuAc-nLc4Cer(d18:1(4E))
Catalysed by ST3GAL6
Reaction pageLeft to rightBalance undeterminableEC 2.4.3.6GO:0005794
Human-GEM MAR08325CC BY 4.0Reference data
MAM01950g+a neolactoside IV(3)-alpha-NeuAc-nLc4Cer(d18:1(4E))GDP+proton+MAM02199g
Catalysed by FUT9
Reaction pageLeft to rightBalance undeterminableEC 2.4.1.-GO:0005794
Human-GEM MAR08326CC BY 4.0Reference data
CMP-N-acetyl-beta-neuraminate+a neolactoside IV(3)-alpha-NeuAc-nLc4Cer(d18:1(4E))MAM00744g+cytidine 5'-monophosphate+proton
Catalysed by ST8SIA5
Reaction pageLeft to rightBalance undeterminableEC 2.4.99.-GO:0005794
Human-GEM MAR08327CC BY 4.0Reference data
a neolactoside nLc4Cer(d18:1(4E))+CMP-N-acetyl-beta-neuraminatea neolactoside IV(3)-alpha-NeuAc-nLc4Cer(d18:1(4E))+CMP+hydron
Catalysed by ST3GAL4 or ST3GAL6
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:18913CC BY 4.0Reference data
a neolactoside IV(3)-alpha-NeuAc-nLc4Cer(d18:1(4E))+watera neolactoside nLc4Cer(d18:1(4E))+N-acetylneuraminate
Catalysed by NEU2
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:47852CC BY 4.0Reference data
a neolactoside IV(3)-alpha-NeuAc-nLc4Cer(d18:1(4E))+GDP-beta-L-fucoseCHEBI:144418+GDP+hydron
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:77715CC BY 4.0Reference data
Other names
1 name
Resolves to: a neolactoside IV(3)-alpha-NeuAc-nLc4Cer(d18:1(4E))
- Also called
- alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(11')-N-acyl-sphing-4-enine