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Proteins/UNIPROT:P78381
Transports uridine diphosphate galactose (UDP-galactose) from the cytosol into the Golgi apparatus, functioning as an antiporter that exchanges UDP-galactose for UMP. It is also able to exchange UDP-galactose for AMP and CMP, and to transport UDP-N-acetylgalactosamine (UDP-GalNAc) and other nucleotide sugars. As a provider of UDP-galactose to galactosyltransferases present in the Golgi apparatus, it is necessary for globotriaosylceramide/globoside (Gb3Cer) synthesis from lactosylceramide..
Function from UniProtKB (P78381), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
2 rows
58 statements
58 statements · 4 reference databases · Subject: SLC35A2 · Sources: Hetionet, Human-GEM, Reactome, Rhea
13 reactions
CHEBI:67119+UMPCHEBI:67119+UMP
Transported by SLC35A2
Reaction pageLeft to rightBalancedcytosol, endoplasmic reticulum
Human-GEM MAR06385CC BY 4.0Reference data
Transported by SLC35A2
Reaction pageReversibleBalancedcytosol, Golgi apparatus
Human-GEM MAR07433CC BY 4.0Reference data
6 names
Resolves to: SLC35A2
UMP+UDP-N-acetyl-alpha-D-glucosamineUMP+UDP-N-acetyl-alpha-D-glucosamine
Transported by SLC35A2 or SLC35D4 or SLC35D2 or SLC35G3 or SLC35A5 or SLC35D1 or SLC35A3
Reaction pageDirection not assertedBalanced
Rhea RHEA:72695CC BY 4.0Reference data
UMP+UDP-alpha-D-galactoseUMP+UDP-alpha-D-galactose
Transported by SLC35A2 or SLC35D1
Reaction pageDirection not assertedBalanced
Rhea RHEA:72703CC BY 4.0Reference data
UMP+UDP-alpha-D-glucoseUMP+UDP-alpha-D-glucose
Transported by SLC35A2 or SLC35D2 or SLC35D1
Reaction pageDirection not assertedBalanced
Rhea RHEA:72731CC BY 4.0Reference data
UDP-N-acetyl-alpha-D-galactosamine+UMPUDP-N-acetyl-alpha-D-galactosamine+UMP
Transported by SLC35A2 or SLC35A5 or SLC35D1
Reaction pageDirection not assertedBalanced
Rhea RHEA:72735CC BY 4.0Reference data
UDP-alpha-D-galactose+AMPUDP-alpha-D-galactose+AMP
Transported by SLC35A2
Reaction pageDirection not assertedBalanced
Rhea RHEA:74599CC BY 4.0Reference data
UDP-alpha-D-galactose+CMPUDP-alpha-D-galactose+CMP
Transported by SLC35A2
Reaction pageDirection not assertedBalanced
Rhea RHEA:74603CC BY 4.0Reference data
UDP-N-acetyl-alpha-D-galactosamine+UDP-alpha-D-galactoseUDP-N-acetyl-alpha-D-galactosamine+UDP-alpha-D-galactose
Transported by SLC35A2
Reaction pageDirection not assertedBalanced
Rhea RHEA:74607CC BY 4.0Reference data
UDP-N-acetyl-alpha-D-glucosamine+UDP-alpha-D-galactoseUDP-N-acetyl-alpha-D-glucosamine+UDP-alpha-D-galactose
Transported by SLC35A2
Reaction pageDirection not assertedBalanced
Rhea RHEA:74611CC BY 4.0Reference data
UDP-alpha-D-galactose+UDP-alpha-D-glucoseUDP-alpha-D-galactose+UDP-alpha-D-glucose
Transported by SLC35A2
Reaction pageDirection not assertedBalanced
Rhea RHEA:74615CC BY 4.0Reference data
Transported by SLC35A2
Reaction pageDirection not assertedBalanced
Rhea RHEA:74619CC BY 4.0Reference data