Compound
D-glucose 6-phosphate
An organophosphate oxoanion resulting from deprotonation of the phosphate OH groups of D-glucopyranose 6-phosphate; major species at pH 7.3.
Definition from ChEBI (CHEBI:61548), read 2026-09-23. CC BY 4.0.
Structure
Loading the model…
- Class
- Organic compound, anion
- Formula
- C6H11O9P
- Mass
- 258.119 g/mol
- Charge
- -2
- InChIKey
- NBSCHQHZLSJFNQ-GASJEMHNSA-L
- SMILES
- O=P([O-])([O-])OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O
- Look it up
- ChEBIPubChemBy InChIKey
Identity from ChEBI, geometry from PubChem. Not evidence.
What it touches on the way
Mechanistic reach
10 entities
10 entities reached.
0 reported hops10 assembled from the scaffold
- G6PDProteinUNIPROT:P11413substrate ofInferred only68 paths34 endpoints
- G6PC1ProteinUNIPROT:P35575substrate ofInferred only33 paths33 endpoints
- GPIProteinUNIPROT:P06744substrate ofInferred only30 paths30 endpoints
- G6PC3ProteinUNIPROT:Q9BUM1substrate ofInferred only11 paths11 endpoints
- G6PC2ProteinUNIPROT:Q9NQR9substrate ofInferred only7 paths7 endpoints
- IMPA1ProteinUNIPROT:P29218substrate ofInferred only6 paths6 endpoints
- ADPGKProteinUNIPROT:Q9BRR6substrate ofInferred only6 paths6 endpoints
- H6PDProteinUNIPROT:O95479substrate ofInferred only4 paths2 endpoints
- ISYNA1ProteinUNIPROT:Q9NPH2substrate ofInferred only3 paths3 endpoints
- SLC37A4ProteinUNIPROT:O43826transported byInferred only2 paths2 endpoints
What the reference databases state
Chemical structure
- D-glucose 6-phosphate has the functional parent D-glucoseCompoundChEBI CHEBI:61548Inferred only
Statements
24 statements
24 statements · 1 reference database · Subject: D-glucose 6-phosphate · Sources: Rhea
- 1D-myo-inositol 3-phosphate is converted to D-glucose 6-phosphateCompoundRhea RHEA:10716Inferred only
- D-glucose 6-phosphate is converted to 1D-myo-inositol 3-phosphateCompoundRhea RHEA:10716Inferred only
- D-glucose 6-phosphate is converted to 6-phospho-D-glucono-1,5-lactoneCompoundRhea RHEA:38215Inferred only
- D-glucose 6-phosphate is converted to 6-phospho-D-glucono-1,5-lactoneCompoundRhea RHEA:15841Inferred only
- D-glucose 6-phosphate is converted to D-glucoseCompoundRhea RHEA:16689Inferred only
- D-glucose 6-phosphate is converted to D-glucoseCompoundRhea RHEA:11460Inferred only
- D-glucose is converted to D-glucose 6-phosphateCompoundRhea RHEA:17825Inferred only
- D-glucose is converted to D-glucose 6-phosphateCompoundRhea RHEA:11460Inferred only
- D-mannose 6-phosphate is converted to D-glucose 6-phosphateCompoundRhea RHEA:85575Inferred only
- D-glucose 6-phosphate is converted to D-mannose 6-phosphateCompoundRhea RHEA:85575Inferred only
- D-glucose 6-phosphate is a substrate of ADPGKProteinRhea RHEA:11460Inferred only
- D-glucose 6-phosphate is a substrate of G6PC1ProteinRhea RHEA:16689Inferred only
Show the remaining 12
- D-glucose 6-phosphate is a substrate of G6PC2ProteinRhea RHEA:16689Inferred only
- D-glucose 6-phosphate is a substrate of G6PC3ProteinRhea RHEA:16689Inferred only
- D-glucose 6-phosphate is a substrate of G6PDProteinRhea RHEA:15841Inferred only
- D-glucose 6-phosphate is a substrate of G6PDProteinRhea RHEA:86243Inferred only
- D-glucose 6-phosphate is a substrate of GPIProteinRhea RHEA:85575Inferred only
- D-glucose 6-phosphate is a substrate of H6PDProteinRhea RHEA:15841Inferred only
- D-glucose 6-phosphate is a substrate of H6PDProteinRhea RHEA:38215Inferred only
- D-glucose 6-phosphate is a substrate of IMPA1ProteinRhea RHEA:16689Inferred only
- D-glucose 6-phosphate is a substrate of ISYNA1ProteinRhea RHEA:10716Inferred only
- D-glucose 6-phosphate is transported by SLC37A1ProteinRhea RHEA:71535Inferred only
- D-glucose 6-phosphate is transported by SLC37A2ProteinRhea RHEA:71535Inferred only
- D-glucose 6-phosphate is transported by SLC37A4ProteinRhea RHEA:71535Inferred only
Reactions
27 reactions
D-glucose 6-phosphate1D-myo-inositol 3-phosphate
Catalysed by ISYNA1
Reaction pageDirection not assertedBalanced
Rhea RHEA:10716CC BY 4.0Reference data
CHEBI:58312+waterD-glucose 6-phosphate+D-glucose
Reaction pageDirection not assertedBalanced
Rhea RHEA:10772CC BY 4.0Reference data
D-glucose+ADP(3-)D-glucose 6-phosphate+AMP+hydron
Catalysed by ADPGK
Reaction pageDirection not assertedBalanced
Rhea RHEA:11460CC BY 4.0Reference data
GDP-alpha-D-glucose+D-glucose 6-phosphateCHEBI:58429+GDP+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:14605CC BY 4.0Reference data
D-glucose 6-phosphate+NADP(3-)6-phospho-D-glucono-1,5-lactone+NADPH(4-)+hydron
Reaction pageLeft to rightBalanced
Rhea RHEA:15841CC BY 4.0Reference data
D-glucose 6-phosphate+waterD-glucose+hydrogenphosphate
Catalysed by IMPA1 or G6PC1 or G6PC3 or G6PC2
Reaction pageLeft to rightBalanced
Rhea RHEA:16689CC BY 4.0Reference data
D-glucose+ATP(4-)D-glucose 6-phosphate+ADP(3-)+hydron
Catalysed by HK1 or GCK or HK2 or HK3 or HKDC1
Reaction pageLeft to rightBalanced
Rhea RHEA:17825CC BY 4.0Reference data
D-glucose 6-phosphate+UDP-alpha-D-glucoseCHEBI:58429+UDP+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:18889CC BY 4.0Reference data
CHEBI:57478+waterD-glucose 6-phosphate+D-glucose
Reaction pageDirection not assertedBalanced
Rhea RHEA:20421CC BY 4.0Reference data
CHEBI:58429+hydrogenphosphateCHEBI:57684+D-glucose 6-phosphate
Reaction pageDirection not assertedBalanced
Rhea RHEA:20864CC BY 4.0Reference data
sn-glycerol 3-phosphate+D-glucoseD-glucose 6-phosphate+glycerol
Reaction pageDirection not assertedBalanced
Rhea RHEA:21288CC BY 4.0Reference data
[phosphate](n)+D-glucose[phosphate](n-1)+D-glucose 6-phosphate+hydron
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:22036CC BY 4.0Reference data
Other names
3 names
Resolves to: D-glucose 6-phosphate
- Also called
- 6-O-phosphonato-D-glucopyranoseD-glucopyranose 6-phosphate dianion
- Systematic name
- D-glucopyranose 6-phosphate