Compound
a ganglioside GM2
An anionic ganglioside obtained by deprotonation of the neuraminosyl carboxy groups of N-acetyl-β-D-galactosaminyl-(1→4)-[α-N-acetylneuraminyl-(2→3)]-β-D-galactosyl-(1→4)-β-D-glucosyl-(1↔1)-ceramide; major species at pH 7.3.
Definition from ChEBI (CHEBI:79218), read 2026-09-23. CC BY 4.0.
Structure
- Class
- Structural class, not a single molecule
- Formula
- C35H56N3O26R2
- Mass
- 934.825 g/mol
- Charge
- -1
- SMILES
- *C(=O)N[C@@H](CO[C@@H]1O[C@H](CO)[C@@H](O[C@@H]2O[C@H](CO)[C@H](O[C@@H]3O[C@H](CO)[C@H](O)[C@H](O)[C@H]3NC(C)=O)[C@H](O[C@]3(C(=O)[O-])C[C@H](O)[C@@H](NC(C)=O)[C@]([H])([C@H](O)[C@H](O)CO)O3)[C@H]2O)[C@H](O)[C@H]1O)[C@@H](*)O
- Look it up
- ChEBI
Identity from ChEBI. Not evidence.
What it touches on the way
Mechanistic reach
5 entities
5 entities reached.
0 reported hops5 assembled from the scaffold
- HEXBProteinUNIPROT:P07686substrate ofInferred only26 paths26 endpoints
- HEXAProteinUNIPROT:P06865substrate ofInferred only22 paths22 endpoints
- NEU2ProteinUNIPROT:Q9Y3R4substrate ofInferred only14 paths14 endpoints
- B3GALT4ProteinUNIPROT:O96024substrate ofInferred only13 paths13 endpoints
- NEU4ProteinUNIPROT:Q8WWR8substrate ofInferred only10 paths10 endpoints
What the reference databases state
Statements
5 statements
5 statements · 1 reference database · Subject: a ganglioside GM2 · Sources: Rhea
- a ganglioside GM2 is a substrate of B3GALT4ProteinRhea RHEA:48280Inferred only
- a ganglioside GM2 is a substrate of HEXAProteinRhea RHEA:47968Inferred only
- a ganglioside GM2 is a substrate of HEXBProteinRhea RHEA:47968Inferred only
- a ganglioside GM2 is a substrate of NEU2ProteinRhea RHEA:48172Inferred only
- a ganglioside GM2 is a substrate of NEU4ProteinRhea RHEA:48172Inferred only
Reactions
4 reactions
a ganglioside GM3+UDP-N-acetyl-alpha-D-galactosaminea ganglioside GM2+UDP+hydron
Catalysed by B4GALNT1
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:43268CC BY 4.0Reference data
a ganglioside GM2+watera ganglioside GM3+N-acetyl-beta-D-galactosamine
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:47968CC BY 4.0Reference data
a ganglioside GM2+watera ganglioside GA2+N-acetylneuraminate
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:48172CC BY 4.0Reference data
a ganglioside GM2+UDP-alpha-D-galactosea ganglioside GM1+UDP+hydron
Catalysed by B3GALT4
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:48280CC BY 4.0Reference data
Other names
1 name
Resolves to: a ganglioside GM2
- Also called
- Ganglioside GM2