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Proteins/UNIPROT:Q96G03
Catalyzes the conversion of the nucleoside breakdown products ribose-1-phosphate and deoxyribose-1-phosphate to the corresponding 5-phosphopentoses. Catalyzes the reversible isomerization of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate but with a lower catalytic efficiency. The mechanism proceeds via the intermediate compound alpha-D-glucose 1,6-bisphosphate. In vitro, also has a low glucose 1,6-bisphosphate synthase activity which is most probably not physiologically relevant..
Function from UniProtKB (Q96G03), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
42 statements
42 statements · 7 reference databases · Subject: PGM2 · Sources: Bgee, Hetionet, Human-GEM, Reactome, Rhea, UniProt, WikiPathways
8 reactions
D-ribose 1-phosphateCHEBI:17797
Catalysed by PGM2
Reaction pageReversibleBalancedEC 5.4.2.2, 5.4.2.7cytosol
Human-GEM MAR04354CC BY 4.0Reference data
MAM01967cD-glucopyranose 6-phosphate
Reaction pageReversibleBalancedEC 5.4.2.2, 5.4.2.5, 5.4.2.6cytosol
Human-GEM MAR04396CC BY 4.0Reference data
MAM00639cCHEBI:16132
3 names
Resolves to: PGM2
Catalysed by PGM2
Reaction pageReversibleBalancedEC 5.4.2.7cytosol
Human-GEM MAR04710CC BY 4.0Reference data
alpha-D-ribose 1-phosphateD-ribose 5-phosphate
Catalysed by PGM2
Reaction pageDirection not assertedBalanced
Rhea RHEA:18793CC BY 4.0Reference data
alpha-D-glucose 1-phosphatealpha-D-glucose 6-phosphate
Reaction pageDirection not assertedBalanced
Rhea RHEA:23536CC BY 4.0Reference data
2-deoxy-alpha-D-ribose 1-phosphate2-deoxy-D-ribose 5-phosphate
Catalysed by PGM2
Reaction pageDirection not assertedBalanced
Rhea RHEA:27658CC BY 4.0Reference data
O-phospho-L-seryl-[protein]+alpha-D-glucose 1-phosphatealpha-D-glucose 1,6-bisphosphate+L-seryl-[protein]
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:68748CC BY 4.0Reference data
alpha-D-glucose 1,6-bisphosphate+L-seryl-[protein]O-phospho-L-seryl-[protein]+alpha-D-glucose 6-phosphate
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:68752CC BY 4.0Reference data