Compound
N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1<->1')-ceramide
An anionic ganglioside that is the conjugate base of N-acetyl-α-neuraminosyl-(2→3)-β-D-galactosyl-ceramide arising from deprotonation of the neuraminosyl carboxy group; major species at pH 7.3.
Definition from ChEBI (CHEBI:82643), read 2026-09-23. CC BY 4.0.
Structure
- Class
- Structural class, not a single molecule
- Formula
- C21H33N2O16R2
- Mass
- 569.491 g/mol
- Charge
- -1
- SMILES
- *C(=O)N[C@@H](CO[C@@H]1O[C@H](CO)[C@H](O)[C@H](O[C@]2(C(=O)[O-])C[C@H](O)[C@@H](NC(C)=O)[C@]([H])([C@H](O)[C@H](O)CO)O2)[C@H]1O)[C@@H](*)O
- Look it up
- ChEBI
Identity from ChEBI. Not evidence.
What it touches on the way
Mechanistic reach
2 entities
2 entities reached.
0 reported hops2 assembled from the scaffold
What the reference databases state
Statements
2 statements
2 statements · 1 reference database · Subject: N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1<->1')-ceramide · Sources: Rhea
- N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1<->1')-ceramide is a substrate of ST3GAL5ProteinRhea RHEA:41780Inferred only
- N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1<->1')-ceramide is a substrate of ST8SIA6ProteinRhea RHEA:48928Inferred only
Reactions
2 reactions
a beta-D-Gal-(1<->1')-ceramide+CMP-N-acetyl-beta-neuraminateN-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1<->1')-ceramide+CMP+hydron
Catalysed by ST3GAL5
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:41780CC BY 4.0Reference data
N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1<->1')-ceramide+CMP-N-acetyl-beta-neuraminateN-acetyl-alpha-neuraminosyl-(2->8)-N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1<->1')-ceramide+CMP+hydron
Catalysed by ST8SIA6
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:48928CC BY 4.0Reference data
Other names
8 names
Resolves to: N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1<->1')-ceramide
- Also called
- alpha-NeuAc-(2->3)-beta-D-Gal-(11')-Cer(1-)GM4Cer(1-)GM4Cer(1−)N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(11')-Cer(1-)N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-ceramide(1-)N-acetyl-α-neuraminosyl-(2→3)-β-D-galactosyl-(1↔1')-Cer(1−)N-acetyl-α-neuraminosyl-(2→3)-β-D-galactosyl-ceramide(1−)α-NeuAc-(2→3)-β-D-Gal-(1↔1')-Cer(1−)