Compound
a fatty acyl-CoA
An acyl-CoA(4−) arising from deprotonation of the phosphate and diphosphate OH groups of any fatty acyl-CoA; major species at pH 7.3.
Definition from ChEBI (CHEBI:77636), read 2026-09-23. CC BY 4.0.
Structure
- Class
- Organic compound, anion
- Formula
- C22H31N7O17P3SR
- Mass
- 790.507 g/mol
- Charge
- -4
- SMILES
- *C(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP(=O)([O-])OP(=O)([O-])OC[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1OP(=O)([O-])[O-]
- Look it up
- ChEBI
Identity from ChEBI. Not evidence.
What it touches on the way
Mechanistic reach
13 entities
13 entities reached.
0 reported hops13 assembled from the scaffold
- AWAT2ProteinUNIPROT:Q6E213substrate ofInferred only48 paths12 endpoints
- CERS4ProteinUNIPROT:Q9HA82substrate ofInferred only18 paths9 endpoints
- CERS1ProteinUNIPROT:P27544substrate ofInferred only16 paths8 endpoints
- CERS6ProteinUNIPROT:Q6ZMG9substrate ofInferred only16 paths8 endpoints
- CERS5ProteinUNIPROT:Q8N5B7substrate ofInferred only14 paths7 endpoints
- GLYATL2ProteinUNIPROT:Q8WU03substrate ofInferred only11 paths11 endpoints
- CERS3ProteinUNIPROT:Q8IU89substrate ofInferred only9 paths9 endpoints
- CERS2ProteinUNIPROT:Q96G23substrate ofInferred only9 paths9 endpoints
- AWAT1ProteinUNIPROT:Q58HT5substrate ofInferred only6 paths6 endpoints
- LPGAT1ProteinUNIPROT:Q92604substrate ofInferred only6 paths6 endpoints
- PIGWProteinUNIPROT:Q7Z7B1substrate ofInferred only6 paths6 endpoints
- ACOT13ProteinUNIPROT:Q9NPJ3substrate ofInferred only6 paths6 endpoints
Show the remaining 1
What the reference databases state
Statements
24 statements
24 statements · 1 reference database · Subject: a fatty acyl-CoA · Sources: Rhea
- a fatty acid is converted to a fatty acyl-CoACompoundRhea RHEA:51580Inferred only
- a fatty acyl-CoA is converted to a fatty acidCompoundRhea RHEA:51580Inferred only
- a fatty acid is converted to a fatty acyl-CoACompoundRhea RHEA:38883Inferred only
- a fatty acyl-CoA is converted to a fatty acidCompoundRhea RHEA:16781Inferred only
- a fatty acyl-CoA is a substrate of ACOT13ProteinRhea RHEA:16781Inferred only
- a fatty acyl-CoA is a substrate of AWAT1ProteinRhea RHEA:38443Inferred only
- a fatty acyl-CoA is a substrate of AWAT2ProteinRhea RHEA:38443Inferred only
- a fatty acyl-CoA is a substrate of AWAT2ProteinRhea RHEA:78263Inferred only
- a fatty acyl-CoA is a substrate of AWAT2ProteinRhea RHEA:77771Inferred only
- a fatty acyl-CoA is a substrate of AWAT2ProteinRhea RHEA:77767Inferred only
- a fatty acyl-CoA is a substrate of CERS1ProteinRhea RHEA:23768Inferred only
- a fatty acyl-CoA is a substrate of CERS1ProteinRhea RHEA:34735Inferred only
Show the remaining 12
- a fatty acyl-CoA is a substrate of CERS2ProteinRhea RHEA:23768Inferred only
- a fatty acyl-CoA is a substrate of CERS3ProteinRhea RHEA:23768Inferred only
- a fatty acyl-CoA is a substrate of CERS4ProteinRhea RHEA:23768Inferred only
- a fatty acyl-CoA is a substrate of CERS4ProteinRhea RHEA:34735Inferred only
- a fatty acyl-CoA is a substrate of CERS5ProteinRhea RHEA:23768Inferred only
- a fatty acyl-CoA is a substrate of CERS5ProteinRhea RHEA:34735Inferred only
- a fatty acyl-CoA is a substrate of CERS6ProteinRhea RHEA:23768Inferred only
- a fatty acyl-CoA is a substrate of CERS6ProteinRhea RHEA:34735Inferred only
- a fatty acyl-CoA is a substrate of GLYATL2ProteinRhea RHEA:64244Inferred only
- a fatty acyl-CoA is a substrate of LPGAT1ProteinRhea RHEA:70599Inferred only
- a fatty acyl-CoA is a substrate of MBOAT4ProteinRhea RHEA:68272Inferred only
- a fatty acyl-CoA is a substrate of PIGWProteinRhea RHEA:60496Inferred only
Reactions
35 reactions
a fatty acyl-CoA+watera fatty acid+coenzyme A(4-)+hydron
Catalysed by ACOT13
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:16781CC BY 4.0Reference data
sphing-4-enine+a fatty acyl-CoAan N-acylsphing-4-enine+coenzyme A(4-)+hydron
Catalysed by CERS1 or CERS6 or CERS3 or CERS5 or CERS2 or CERS4
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:23768CC BY 4.0Reference data
CHEBI:70829+a fatty acyl-CoACHEBI:70845+coenzyme A(4-)+hydron
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:34603CC BY 4.0Reference data
CHEBI:70771+a fatty acyl-CoACHEBI:70846+coenzyme A(4-)+hydron
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:34731CC BY 4.0Reference data
a fatty acyl-CoA+sphinganinean N-acylsphinganine+coenzyme A(4-)+hydron
Catalysed by CERS1 or CERS6 or CERS5 or CERS4
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:34735CC BY 4.0Reference data
(4R)-hydroxysphinganine+a fatty acyl-CoAan N-acyl-(4R)-4-hydroxysphinganine+coenzyme A(4-)+hydron
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:35651CC BY 4.0Reference data
a fatty acyl-CoA+2NADPH(4-)+2hydronCHEBI:77396+2NADP(3-)+coenzyme A(4-)
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:36303CC BY 4.0Reference data
a long chain fatty alcohol+a fatty acyl-CoAa long-chain alcohol wax ester+coenzyme A(4-)
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:38443CC BY 4.0Reference data
a fatty acid+ATP(4-)+coenzyme A(4-)a fatty acyl-CoA+AMP+diphosphate(3-)
Catalysed by ACSL3
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:38883CC BY 4.0Reference data
CHEBI:64885+a fatty acyl-CoACHEBI:71985+coenzyme A(4-)+hydron
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:39991CC BY 4.0Reference data
heptadecasphing-4-enine+a fatty acyl-CoACHEBI:84445+coenzyme A(4-)+hydron
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:44424CC BY 4.0Reference data
hexadecasphinganine+a fatty acyl-CoACHEBI:82881+coenzyme A(4-)+hydron
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:44692CC BY 4.0Reference data
Other names
2 names
Resolves to: a fatty acyl-CoA
- Also called
- fatty acyl-coenzyme A(4-)fatty acyl-coenzyme A(4−)