Loading the page.
Proteins/UNIPROT:P19526
Catalyzes the transfer of L-fucose, from a guanosine diphosphate-beta-L-fucose, to the terminal galactose residue of glycoconjugates through an alpha(1,2) linkage leading to H antigen synthesis that is an intermediate substrate in the synthesis of ABO blood group antigens. H antigen is essential for maturation of the glomerular layer of the main olfactory bulb, in cell migration and early cell-cell contacts during tumor associated angiogenesis. Preferentially fucosylates soluble lactose and to a lesser extent fucosylates glycolipids gangliosides GA1 and GM1a (By similarity)..
Function from UniProtKB (P19526), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
308 statements
308 statements · 6 reference databases · Subject: FUT1 · Sources: gene ontology, Hetionet, Human-GEM, Reactome, Rhea, WikiPathways · Rows fetched: 300
23 reactions
MAM01912c+MAM01950cGDP+MAM01958c+proton
Reaction pageLeft to rightBalance undeterminableEC 2.4.1.69cytosol
Human-GEM MAR00813CC BY 4.0Reference data
MAM01950c+a beta-D-Gal-(1->3)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer(d18:1(4E))GDP+proton+alpha-L-fucosyl-(1->2)- beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine
9 names
Resolves to: FUT1
Reaction pageLeft to rightBalance undeterminableEC 2.4.1.69cytosol
Human-GEM MAR00864CC BY 4.0Reference data
MAM01873c+MAM01950cGDP+proton+MAM03091c
Reaction pageLeft to rightBalance undeterminableEC 2.4.1.69cytosol
Human-GEM MAR00866CC BY 4.0Reference data
MAM01950c+MAM02592cGDP+proton+MAM03094c
Reaction pageLeft to rightBalance undeterminableEC 2.4.1.69cytosol
Human-GEM MAR00880CC BY 4.0Reference data
MAM01950c+a neolactoside nLc4Cer(d18:1(4E))GDP+proton+MAM02196c
Reaction pageLeft to rightBalance undeterminableEC 2.4.1.69cytosol
Human-GEM MAR00883CC BY 4.0Reference data
MAM01876c+MAM01950cGDP+proton+MAM03097c
Reaction pageLeft to rightBalance undeterminableEC 2.4.1.69cytosol
Human-GEM MAR00886CC BY 4.0Reference data
MAM01950c+MAM02594cGDP+proton+MAM03137c
Reaction pageLeft to rightBalance undeterminableEC 2.4.1.69cytosol
Human-GEM MAR00898CC BY 4.0Reference data
MAM01878c+MAM01950cMAM01879c+GDP+proton
Reaction pageLeft to rightBalance undeterminableEC 2.4.1.69cytosol
Human-GEM MAR00904CC BY 4.0Reference data
MAM01950c+MAM02186cGDP+proton+MAM02490c
Reaction pageLeft to rightBalance undeterminableEC 2.4.1.69cytosol
Human-GEM MAR00908CC BY 4.0Reference data
MAM01950c+MAM02490cMAM01881c+GDP+proton
Reaction pageLeft to rightBalance undeterminableEC 2.4.1.69cytosol
Human-GEM MAR00909CC BY 4.0Reference data
2MAM01950g+MAM03584gMAM01856g+2GDP+2proton
Catalysed by FUT1
Reaction pageLeft to rightBalance undeterminableEC 2.4.1.69Golgi apparatus
Human-GEM MAR01083CC BY 4.0Reference data
MAM01912g+MAM01950gMAM01861g+GDP+proton
Reaction pageLeft to rightBalance undeterminableEC 2.4.1.69Golgi apparatus
Human-GEM MAR08221CC BY 4.0Reference data