Loading the page.
Proteins/UNIPROT:Q9UBX8
Catalyzes the synthesis of lactosylceramide (LacCer) via the transfer of galactose from UDP-galactose to glucosylceramide (GlcCer). LacCer is the starting point in the biosynthesis of all gangliosides (membrane-bound glycosphingolipids) which play pivotal roles in the CNS including neuronal maturation and axonal and myelin formation (By similarity)..
Function from UniProtKB (Q9UBX8), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
37 statements
37 statements · 7 reference databases · Subject: B4GALT6 · Sources: Bgee, Hetionet, Human-GEM, Reactome, Rhea, UniProt, WikiPathways
5 reactions
D-glucosyl-N-acylsphingosine+CHEBI:67119proton+a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E))+UDP
Catalysed by GLT8D1 or B4GALT7 or PIGV or B4GALT1 or GALNT7 or B4GALT2 or A4GNT or B4GALT6 or PIGZ or GLT8D2 or B4GALT4 or GCNT7 and 23 more alternatives
9 names
Resolves to: B4GALT6
Reaction pageLeft to rightBalance undeterminableEC 2.4.1.-endoplasmic reticulum
Human-GEM MAR00765CC BY 4.0Reference data
CHEBI:12947+CHEBI:67119MAM01694c+proton+UDP
Catalysed by GLT8D1 or B4GALT7 or B4GALT1 or B4GALT2 or A4GNT or B4GALT6 or GLT8D2 or B4GALT4 or GCNT7 or GBGT1 or B4GALT5 or B4GALT3 and 10 more alternatives
Reaction pageLeft to rightBalance undeterminableEC 2.4.1.-cytosol
Human-GEM MAR00924CC BY 4.0Reference data
CHEBI:12947+CHEBI:67119MAM01694g+proton+UDP
Catalysed by GLT8D1 or B4GALT7 or POMGNT1 or B4GALT1 or GALNT7 or B4GALT2 or A4GNT or B4GALT6 or PIGZ or GLT8D2 or B4GALT4 or GCNT7 and 16 more alternatives
Reaction pageLeft to rightBalance undeterminableEC 2.4.1.-Golgi apparatus
Human-GEM MAR00925CC BY 4.0Reference data
D-glucosyl-N-acylsphingosine+CHEBI:67119proton+a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E))+UDP
Catalysed by GLT8D1 or B4GALT7 or B4GALT1 or B4GALT2 or A4GNT or B4GALT6 or GLT8D2 or B4GALT4 or GCNT7 or GBGT1 or B4GALT5 or B4GALT3 and 12 more alternatives
Reaction pageLeft to rightBalance undeterminableEC 2.4.1.-cytosol
Human-GEM MAR00926CC BY 4.0Reference data
a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine+UDP-alpha-D-galactosea beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E))+UDP+hydron
Catalysed by B4GALT5 or B4GALT6
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:31495CC BY 4.0Reference data