Compound

an all-trans-retinyl ester

A carboxylic ester of retinol formed by condensation of the hydroxy group of retinol with a carboxy group.

Definition from MeSH (D000084562), National Library of Medicine, read 2026-09-23. NLM revises MeSH; this copy may not reflect its current record.

CHEBI:63410ChEBI

Open in the graph

Structure

2D depiction

Class: Organic compound
Formula: C21H29O2R
Mass: 313.454 g/mol
Charge: 0
SMILES: *C(=O)OC/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CCCC1(C)C
Look it up: ChEBI

Identity from ChEBI. Not evidence.

What it touches on the way

Mechanistic reach

21 entities

21 entities reached.

0 reported hops21 assembled from the scaffold

Show the remaining 9

What the reference databases state

Chemical structure

an all-trans-retinyl ester has the functional parent all-trans-retinolCompoundChEBI CHEBI:63410Inferred only

Statements

23 statements

23 statements · 2 reference databases · Subject: an all-trans-retinyl ester · Sources: Human-GEM, Rhea

Order

an all-trans-retinyl ester is metabolised by CES1ProteinHuman-GEM MAR06636Inferred only
an all-trans-retinyl ester is metabolised by CES2ProteinHuman-GEM MAR06636Inferred only
an all-trans-retinyl ester is metabolised by CES3ProteinHuman-GEM MAR06636Inferred only
an all-trans-retinyl ester is metabolised by CES5AProteinHuman-GEM MAR06636Inferred only
an all-trans-retinyl ester is a substrate of AADACProteinHuman-GEM MAR06636Inferred only
an all-trans-retinyl ester is a substrate of CELProteinHuman-GEM MAR06636Inferred only
an all-trans-retinyl ester is a substrate of DAGLAProteinHuman-GEM MAR06636Inferred only
an all-trans-retinyl ester is a substrate of DAGLBProteinHuman-GEM MAR06636Inferred only
an all-trans-retinyl ester is a substrate of LIPCProteinHuman-GEM MAR06636Inferred only
an all-trans-retinyl ester is a substrate of LIPEProteinHuman-GEM MAR06636Inferred only
an all-trans-retinyl ester is a substrate of LIPFProteinHuman-GEM MAR06636Inferred only
an all-trans-retinyl ester is a substrate of LIPGProteinHuman-GEM MAR06636Inferred only

Show the remaining 11

an all-trans-retinyl ester is a substrate of PNLIPProteinHuman-GEM MAR06636Inferred only
an all-trans-retinyl ester is a substrate of PNLIPRP1ProteinHuman-GEM MAR06636Inferred only
an all-trans-retinyl ester is a substrate of PNLIPRP2ProteinHuman-GEM MAR06636Inferred only
an all-trans-retinyl ester is a substrate of PNLIPRP3ProteinHuman-GEM MAR06636Inferred only
an all-trans-retinyl ester is a substrate of PNPLA2ProteinHuman-GEM MAR06636Inferred only
an all-trans-retinyl ester is a substrate of PNPLA3ProteinHuman-GEM MAR06636Inferred only
an all-trans-retinyl ester is a substrate of PNPLA4ProteinRhea RHEA:38555Inferred only
an all-trans-retinyl ester is a substrate of PNPLA4ProteinHuman-GEM MAR06636Inferred only
an all-trans-retinyl ester is a substrate of RBP4ProteinHuman-GEM MAR06636Inferred only
an all-trans-retinyl ester is a substrate of RPE65ProteinHuman-GEM MAR06637Inferred only
an all-trans-retinyl ester is a substrate of RPE65ProteinRhea RHEA:31771Inferred only

Reactions

17 reactions

an all-trans-retinyl ester
Reaction pageReversibleBalance undeterminableextracellular space
Human-GEM MAR00666CC BY 4.0Reference data
1,2-diacyl-sn-glycero-3-phosphocholine(1+)+all-trans-retinol1-O-acyl-sn-glycero-3-phosphocholine(1+)+an all-trans-retinyl ester
Catalysed by LRAT
Reaction pageLeft to rightBalance undeterminableEC 2.3.1.135cytosol
Human-GEM MAR01501CC BY 4.0Reference data
11-cis-retinol+1,2-diacyl-sn-glycero-3-phosphocholine(1+)1-O-acyl-sn-glycero-3-phosphocholine(1+)+an all-trans-retinyl ester
Reaction pageLeft to rightBalance undeterminableEC 1.14.14.1cytosol
Human-GEM MAR01506CC BY 4.0Reference data
an all-trans-retinyl esteran all-trans-retinyl ester
Reaction pageLeft to rightBalance undeterminablecytosol, extracellular space
Human-GEM MAR01698CC BY 4.0Reference data
1,2-diacyl-sn-glycero-3-phosphocholine(1+)+all-trans-retinolMAM00535c+an all-trans-retinyl ester
Catalysed by DGAT2 or RBP2 or RBP1 or LRAT or AWAT2 or DGAT1
Reaction pageLeft to rightBalance undeterminableEC 2.3.1.135, 2.3.1.75cytosol
Human-GEM MAR06635CC BY 4.0Reference data
water+an all-trans-retinyl esterproton+all-trans-retinol+fatty acid
Catalysed by PNPLA4 or LIPE or PNPLA3 or LIPG or AADAC or DAGLA or RBP4 or CES5A or DAGLB or LIPC or CEL or CES3 and 8 more alternatives
Reaction pageLeft to rightBalance undeterminableEC 3.1.1.1, 3.1.1.3cytosol
Human-GEM MAR06636CC BY 4.0Reference data
water+an all-trans-retinyl ester11-cis-retinol+proton+fatty acid
Catalysed by RPE65
Reaction pageLeft to rightBalance undeterminableEC 3.1.1.64cytosol
Human-GEM MAR06637CC BY 4.0Reference data
11-cis-retinol+1,2-diacyl-sn-glycero-3-phosphocholine(1+)MAM00535c+an all-trans-retinyl ester
Catalysed by DGAT2 or RBP2 or RBP1 or LRAT or AWAT2 or DGAT1 or AWAT1
Reaction pageLeft to rightBalance undeterminableEC 2.3.1.135, 2.3.1.75cytosol
Human-GEM MAR06639CC BY 4.0Reference data
all-trans-retinol+an acyl-CoAan all-trans-retinyl ester+coenzyme A(4-)
Catalysed by DGAT1 or PNPLA4 or AWAT2 or DGAT2
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:11488CC BY 4.0Reference data
all-trans-retinol--[retinol-binding protein]+a 1,2-diacyl-sn-glycero-3-phosphocholineapo--[retinol-binding protein]+an all-trans-retinyl ester+a 2-acyl-sn-glycero-3-phosphocholine
Catalysed by LRAT
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:17469CC BY 4.0Reference data
an all-trans-retinyl ester+water11-cis-retinol+a fatty acid+hydron
Catalysed by RPE65
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:31771CC BY 4.0Reference data
an all-trans-retinyl ester+water13-cis-retinol+a fatty acid+hydron
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:31779CC BY 4.0Reference data

Show the remaining 5

Other names

2 names

Resolves to: an all-trans-retinyl ester

Also called: all-trans retinyl esterall-trans-retinyl esters